ID   A0A1A9WQ84_9MUSC        Unreviewed;       946 AA.
AC   A0A1A9WQ84;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
OS   Glossina brevipalpis.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=37001 {ECO:0000313|EnsemblMetazoa:GBRI027954-PA, ECO:0000313|Proteomes:UP000091820};
RN   [1] {ECO:0000313|Proteomes:UP000091820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000091820};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GBRI027954-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GBRI027954-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A1A9WQ84; -.
DR   STRING; 37001.A0A1A9WQ84; -.
DR   EnsemblMetazoa; GBRI027954-RA; GBRI027954-PA; GBRI027954.
DR   VEuPathDB; VectorBase:GBRI027954; -.
DR   OrthoDB; 50983at2759; -.
DR   Proteomes; UP000091820; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR   CDD; cd22423; KH-I_MEX3_rpt1; 1.
DR   CDD; cd22424; KH-I_MEX3_rpt2; 1.
DR   CDD; cd16518; RING-HC_MEX3; 1.
DR   Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR047228; KH-I_MEX3_rpt1.
DR   InterPro; IPR047226; KH-I_MEX3_rpt2.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR047227; MEX3.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR23285:SF7; LD09246P1; 1.
DR   PANTHER; PTHR23285; RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00013; KH_1; 2.
DR   Pfam; PF13920; zf-C3HC4_3; 1.
DR   SMART; SM00322; KH; 2.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50084; KH_TYPE_1; 2.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00117}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          895..934
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          57..83
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        57..81
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   946 AA;  102638 MW;  1C0AAC96F62A4FAA CRC64;
     MSSIKTATIL NTAVTSEICS PSNVFTPTIA AKVSSTSTCS SASFCFENAI ILSGSSGCSS
     LSNSPTSSTS TTGSLSSPTP ATKILDDPFP SKVVNGEFEE EVLKCPPQNP LLAKFKLSED
     NAIKKENDIS DEQSQILLDD FSSDFSALHN SRHHHLQQFQ SQYQQQQMVH HSIQSLNTDD
     ARTLQLAVEL SMMGLKDQMI NSQLQQLRFQ ATENQFPQYN SAYQVNTLSK TLLPIHNTTV
     LTNPKYTGNQ STSGHFNTPN FLNTPTCLAI SEERSKKSQN MTECVPVPSS EHVAEIVGRQ
     GCKIKALRAK TNTYIKTPVR NEEPVFVVTG RKEDVAKAKR EILSAAEHFT LIRATRRAGE
     GTGVHNGMTG VGCIPKNALN GGNGIQGQVT IQVRVPYRVV GLVVGPKGNT IKHIQHETQT
     YIVTPSRDKE PIFEVTGLPD NVQAARKHIE AHIATRTGGE TLGNSSRSAL FMPGNLSASP
     TIHTPIPAPT TSLTTAMSLS HSTTPHEFHL AIGQEDSKDV QKIVNTSINQ ESVPQNAALQ
     SALMFTTPSS SQRTVSSTVQ DELNLHNMLA SPLPILQIVP KINTLIPTAT SSVENMSLEN
     TPHSSNDESL QAMNTINKIV NDEIHVELLS TIYKTGIESA FESFQQSVGE VVNQLQDSET
     NSNKELANTL TSLSSSSGHI AEFPSTKSAE IDIEPSMTST SHPINQVHLN GMMNFHMTTN
     KADYPNHVIK TSSGFESDLD QQATNIHKLA SFMTNGGPVR SISSNAILRN LKSNFNEISN
     GANNVSALTR SCSSASSTSA SSSKSLSQNN STASAATFWK RVSLGDSTEI DEGIGESPNI
     WKLPKKLAVV TSSYCPASIS PTDQEYFNYS QFRNKPIIIH GPMEHNGKTK IKRDCCICHE
     KEMVAALIPC GHKMFCVDCA NSICSGKEPT CPFCCMRVYQ AVKILN
//