ID   A0A1A9WSM5_9MUSC        Unreviewed;      1043 AA.
AC   A0A1A9WSM5;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=Sema domain-containing protein {ECO:0000259|PROSITE:PS51004};
OS   Glossina brevipalpis.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=37001 {ECO:0000313|EnsemblMetazoa:GBRI030537-PA, ECO:0000313|Proteomes:UP000091820};
RN   [1] {ECO:0000313|Proteomes:UP000091820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000091820};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GBRI030537-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GBRI030537-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR   AlphaFoldDB; A0A1A9WSM5; -.
DR   STRING; 37001.A0A1A9WSM5; -.
DR   EnsemblMetazoa; GBRI030537-RA; GBRI030537-PA; GBRI030537.
DR   VEuPathDB; VectorBase:GBRI030537; -.
DR   OrthoDB; 5399685at2759; -.
DR   Proteomes; UP000091820; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR   Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 6.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR002165; Plexin_repeat.
DR   InterPro; IPR016201; PSI.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR027231; Semaphorin.
DR   InterPro; IPR000884; TSP1_rpt.
DR   InterPro; IPR036383; TSP1_rpt_sf.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR11036; SEMAPHORIN; 1.
DR   PANTHER; PTHR11036:SF79; SEMAPHORIN 5C, ISOFORM A; 1.
DR   Pfam; PF01437; PSI; 1.
DR   Pfam; PF01403; Sema; 1.
DR   Pfam; PF00090; TSP_1; 5.
DR   PRINTS; PR01705; TSP1REPEAT.
DR   SMART; SM00423; PSI; 1.
DR   SMART; SM00630; Sema; 1.
DR   SMART; SM00209; TSP1; 6.
DR   SUPFAM; SSF103575; Plexin repeat; 1.
DR   SUPFAM; SSF101912; Sema domain; 1.
DR   SUPFAM; SSF82895; TSP-1 type 1 repeat; 6.
DR   PROSITE; PS51004; SEMA; 1.
DR   PROSITE; PS50092; TSP1; 6.
PE   4: Predicted;
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        909..932
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..438
FT                   /note="Sema"
FT                   /evidence="ECO:0000259|PROSITE:PS51004"
SQ   SEQUENCE   1043 AA;  118089 MW;  358A215A19A0AA31 CRC64;
     MVTAKRFNEP DITSYSEMLF DVARNQLIVG ARDTLYRMSF DLEIMERANW EAEPSQITMC
     QAKGQSEHLC RNYVRVLQTY SENKLYACGT NAFNPNCTLL QMENLQITGH ESGVGKCPFN
     PLSNITSVMT QNGKIFVGTA TDFSGSDAAI LRSAVQQYNN SIIRTKQSNN NWLNNPQFVG
     SFEAGDFVYF LFRETAVEYM NCGKVIYSRI ARVCKNDAGG DHILRDNWTS FLKARLNCSL
     PGEYPFYFNE IQDMIYSQDE NILYATFTTP DNSIHGSAVC AYNLTAINDA FAGFFKYQEN
     IESPWKTVRG HDNGQFRCEG RLTQKHLLES SKYQLVDRAV QPITNKPLYY SKLERFSHIA
     VDIVHTKTEK VNILYVITEP NVIKKLSIKV DLARGGEAQA CLVEVWNMQN HNILNTEYLK
     VTDSLYVGAE QSLIRIPAQH CSRHVSRISC LNSMDPYCGW NVLLERCTPQ ELSIDLTKYW
     IQPDVLKCPV LTAPIDGAWS TWSGWYKCKK HGEDDGECRC RTRECNNPKP QNGGMDCEGI
     TTEVINCTVH GGWTEWSAWS ACSQTCGIAV KTRRRSCGNP KPGFGGRTCV GPERAEMYCS
     HLPPCPAPKP AAVDGGWGPW GEWSECSALC GGGFRIRRRE CNDPRPQNGG MECPGCNIDY
     EDCNMHSCPE IRKLSSWTPW LVHYNKSQDP EVSDTIYTEK RFRFVCRAIS PDPSSVHISL
     VKTENRICRE GVCQRHNDMN ALEEIEHAEW GACNVSCGGG VQYRHFGESK HRGRHMQSRA
     CNIHPCPDSS SINEVISMHE WSCWSDWSTC SVTCGVGLRR RTRKCLGGHD KLCHGRSLEE
     EKCEMKPCED FIGWNTWSEW SDCTSDGIRF RHRKCLIDNP DVNECRGEEF EKTACVPGLC
     EGTQAASTAT LGSIIAAVIL LYALTIFMTF WLTRRHFMPP VVLLKNNTPT AVNYDSYSNQ
     YSSLPTKDIY DVRPKVKRQS SFNMCSSPTS KNFNASTLNR NNISHNHTPK VLAKTYNDCE
     TGTLKRNSHA LNNYRSNLDD EKF
//