ID   A0A1A9X418_9MUSC        Unreviewed;       641 AA.
AC   A0A1A9X418;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
OS   Glossina brevipalpis.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=37001 {ECO:0000313|EnsemblMetazoa:GBRI043472-PA, ECO:0000313|Proteomes:UP000091820};
RN   [1] {ECO:0000313|Proteomes:UP000091820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000091820};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GBRI043472-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GBRI043472-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR   AlphaFoldDB; A0A1A9X418; -.
DR   STRING; 37001.A0A1A9X418; -.
DR   EnsemblMetazoa; GBRI043472-RA; GBRI043472-PA; GBRI043472.
DR   VEuPathDB; VectorBase:GBRI043472; -.
DR   OrthoDB; 3109291at2759; -.
DR   Proteomes; UP000091820; Unassembled WGS sequence.
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd00312; Esterase_lipase; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   InterPro; IPR002168; Lipase_GDXG_HIS_AS.
DR   PANTHER; PTHR43142; CARBOXYLIC ESTER HYDROLASE; 1.
DR   PANTHER; PTHR43142:SF1; CARBOXYLIC ESTER HYDROLASE; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR   PROSITE; PS01173; LIPASE_GDXG_HIS; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Serine esterase {ECO:0000256|ARBA:ARBA00022487}.
FT   DOMAIN          91..629
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   641 AA;  72400 MW;  EDB1AC8F0CED5B79 CRC64;
     MFKQIYCLLV ILFTIVLLCG SYVQLSKSIA IAPATFSTAM TKAGKFSNKL TETAAWKTLT
     SHPNSLVQLL PSRAMRVVQE VVRTFRKDSN VIVRTTAGRI RGRYQKYRSG ERGGYYSFKG
     IRYGLPPIGD RRFRAAEPER PWLGIRDASR EGHSCPHKNM ILDTFKGKED CLFLNVFTSK
     IPKGDNNPEM PVMVWLHGGG YSFGSGNTFL YGPDYLVAEN VVLVTLNYRL GPLGFLTAGP
     NAPGNQGLKD QLLALKWVRD NIAAFGGDPN QVTVFGESAG GSSVQILMLS PLSKGLFHRA
     ISESGSALNP WAMGESSALK ASRLAANLGY IGSNNTDDIL EFLKRSPAMK LIEGAPTTLT
     EEDYRNNIGL PFVPVVEGYW NDGDKTVYTE SPLITENPIE LYRKQKFQKN VPYLTGYNAH
     EAMLFIRRLR KNPNLLQIIE NDFERMIPKD LNVTTERGRV TREIRQFYLG NKSVSTDSVD
     EMIALLTDLM FLQGIRRSAR YHARYGSSPV YMYRFAFDGA LGLYKRMLGL QRPGVCHGDE
     LGYLFKFGFF NLNLDPNSME VVVKNRMVRM WTNFAKYGNP TPAHKEDNLI NTVWLPINPD
     SVMDNLNFMD ISATLDISRN PEFERQQFWD YMYEHYNGNA M
//