ID A0A1A9Z3K8_GLOPL Unreviewed; 412 AA.
AC A0A1A9Z3K8;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Cycle {ECO:0008006|Google:ProtNLM};
OS Glossina pallidipes (Tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=7398 {ECO:0000313|EnsemblMetazoa:GPAI002859-PA, ECO:0000313|Proteomes:UP000092445};
RN [1] {ECO:0000313|Proteomes:UP000092445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000092445};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GPAI002859-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPAI002859-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A1A9Z3K8; -.
DR STRING; 7398.A0A1A9Z3K8; -.
DR EnsemblMetazoa; GPAI002859-RA; GPAI002859-PA; GPAI002859.
DR VEuPathDB; VectorBase:GPAI002859; -.
DR Proteomes; UP000092445; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR001067; Nuc_translocat.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR PANTHER; PTHR23042; CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS; 1.
DR PANTHER; PTHR23042:SF99; PROTEIN CYCLE; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF14598; PAS_11; 1.
DR PRINTS; PR00785; NCTRNSLOCATR.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 32..85
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 104..168
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 315..366
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 19..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..45
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 412 AA; 47528 MW; AE8D8247E7E7FAE9 CRC64;
MNCNNMEFCD NLEELDDETY DEEKSARTTD ENRKQNHSEI EKRRRDKMNT YINELSSMIP
ICYAMHRKLD KLTVLRMAVQ HLRSIRGAVH AYSGADCKPT FLSDQEMKML ILQAAEGFLF
VVGCDRGRIL YVSESVSQVL NCTQSDLLGQ SWFDFLHQKD VAKVKEQLSS LDPCPRERYI
DAKTMLPVKA DIPQSLCRLC PGARRSFFCR MKLKASGSQI KEESDTSSSS RSSTKRRSKL
LNEDKYRVIQ CTGYLKSWTP IKEEDQDNEN ENQISNLSCL VAIGRIPSNV LENQTPASLD
NHPNIRHVNF LSRHSVDGKF LFIDQRATLA VGFLPQEILG SSFYEYFHHE DVPALAESHK
LVLQVAEKVT TQVYRFRCKD NSFIQLQSEW RAFKNPWTTE IEYIMAKNSV FL
//
