ID   A0A1A9Z5V3_GLOPL        Unreviewed;       549 AA.
AC   A0A1A9Z5V3;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Transcription factor grauzone {ECO:0008006|Google:ProtNLM};
OS   Glossina pallidipes (Tsetse fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=7398 {ECO:0000313|EnsemblMetazoa:GPAI004781-PA, ECO:0000313|Proteomes:UP000092445};
RN   [1] {ECO:0000313|Proteomes:UP000092445}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000092445};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GPAI004781-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPAI004781-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A1A9Z5V3; -.
DR   STRING; 7398.A0A1A9Z5V3; -.
DR   EnsemblMetazoa; GPAI004781-RA; GPAI004781-PA; GPAI004781.
DR   VEuPathDB; VectorBase:GPAI004781; -.
DR   Proteomes; UP000092445; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.1800.20; -; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 6.
DR   InterPro; IPR012934; Znf_AD.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR24409:SF295; LD43035P; 1.
DR   PANTHER; PTHR24409; ZINC FINGER PROTEIN 142; 1.
DR   Pfam; PF07776; zf-AD; 1.
DR   Pfam; PF00096; zf-C2H2; 4.
DR   Pfam; PF13912; zf-C2H2_6; 1.
DR   SMART; SM00868; zf-AD; 1.
DR   SMART; SM00355; ZnF_C2H2; 10.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR   PROSITE; PS51915; ZAD; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 7.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW   ProRule:PRU01263}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU01263};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00042}.
FT   DOMAIN          2..79
FT                   /note="ZAD"
FT                   /evidence="ECO:0000259|PROSITE:PS51915"
FT   DOMAIN          293..321
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          325..352
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          354..382
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          381..405
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          441..469
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          470..497
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          498..526
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   BINDING         4
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT   BINDING         7
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT   BINDING         52
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT   BINDING         55
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
SQ   SEQUENCE   549 AA;  64074 MW;  48106E9E33D57869 CRC64;
     MLFCRLCLTK ANDFKHLCDE KGQGSEIYHI TVKYFDPMWF SFKDNVESKV ICNKCWQHIN
     EFYCFQENVM KAQTQLEENS KNLRLLIEMK NGNDLEPVKG MHDGNQIECS NYLKAYKSES
     CQTSEDDGQS NSELQKIIEL PRRSKRLKNA ADEAPNVKQK YNTAKNSCSP GEEICKNLQT
     NQRRKKPINL NNDVSNNNFL SSREKKNINK SSNKCQENHL KKTLEYDAFI SEWKRDLDCV
     ICNNSLPNFT ILRTHFRQEH PDQKCYVVCC KHKLYDRFQL VEHIRLHIDP NTFKCEVCGK
     CATNSRNLKK HMREMHSDDK NERQFECNVC NKRFARKAIL KAHMDIHATG NKDHLCKVCG
     KGFVLLSRLR IHERSVHDAI RVCDQCGKKI AGKYALKQHL LEHSGIIKPT WSCDQCDAKL
     NSHYSLKRHK EIKHNDGSTL YICSECGKCS TSVHALRNHK KNVHQTIRKY KCNICDKAFK
     IALTLREHMA SHTGEELYKC PHCPKTFKVS SNMHHHRKKF HPLEWAQGRK QRKQRSDVDS
     SLISNEVIL
//