ID   A0A1A9ZAH5_GLOPL        Unreviewed;       851 AA.
AC   A0A1A9ZAH5;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Sema domain-containing protein {ECO:0000259|PROSITE:PS51004};
OS   Glossina pallidipes (Tsetse fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=7398 {ECO:0000313|EnsemblMetazoa:GPAI008631-PA, ECO:0000313|Proteomes:UP000092445};
RN   [1] {ECO:0000313|Proteomes:UP000092445}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000092445};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GPAI008631-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPAI008631-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR   AlphaFoldDB; A0A1A9ZAH5; -.
DR   STRING; 7398.A0A1A9ZAH5; -.
DR   EnsemblMetazoa; GPAI008631-RA; GPAI008631-PA; GPAI008631.
DR   VEuPathDB; VectorBase:GPAI008631; -.
DR   Proteomes; UP000092445; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   CDD; cd11237; Sema_1A; 1.
DR   Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR002165; Plexin_repeat.
DR   InterPro; IPR016201; PSI.
DR   InterPro; IPR042068; SEM1A_sema_dom.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR027231; Semaphorin.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR11036:SF131; MIP07328P; 1.
DR   PANTHER; PTHR11036; SEMAPHORIN; 1.
DR   Pfam; PF01437; PSI; 1.
DR   Pfam; PF01403; Sema; 1.
DR   SMART; SM00423; PSI; 1.
DR   SMART; SM00630; Sema; 1.
DR   SUPFAM; SSF103575; Plexin repeat; 1.
DR   SUPFAM; SSF101912; Sema domain; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   4: Predicted;
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        65..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        743..766
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          87..558
FT                   /note="Sema"
FT                   /evidence="ECO:0000259|PROSITE:PS51004"
SQ   SEQUENCE   851 AA;  94765 MW;  EBF9E84A47F6BBC5 CRC64;
     MIKLQAPLNT NNHRYCKLRN SSCSNINHNR NNNNNNNNYC SRSKSNNNMH TNMLILVATV
     KKRSLLLLTF VLLLICLCQL CRPALAWMPD VRPDLQAKQD KILAKFFGNT TDYFKVLHHD
     DYTILIGARD VMYNISLNGL RENSRIQWFS SDADRELCAL KGKHESDCHN YIRVFAHLED
     GQILLCGTNS YKPRCRHYAP TVDEVHGNSV FTYEIVRDVE AQGLCPYSPV HNSTYAFADG
     QLYSATVADF SGGDPLIYRE NLRTEQYDLK QLNQPDFVGA VERNGFVMFF FREIAMEFMN
     FGKTVYSRVG RVCKNDRGGP YTLSKSWTSF LKARLNCSVP GEFPFYFDEI QAVSPVMESP
     TNPLIYAVFT TSVNAISGSA VCAFNIDDIM EAFQGRFKSQ KDSQSQWLPV QEEQVPEPRP
     GQCVDDSRTL SSIAVNFVKN HPLMETSVPA VFGRPLLKKV NLFHRLTTIA VDPQVRGLDG
     EFHDVIYTGT DDGKVTKFIN IPTATNGGNS ASFDELKFVL ISETQVLPIG VPVRELVVSF
     KTNTLLVVSD GSLVTVPLHH CNHIVDCANC LALQDPNCAW DQQTHECRSL SIANHKFGTK
     MFLQSLNTSK WAAKNLCPKL GKGIVIAEGP AVSLGIVTDN ALDASMNIPS HKDEDLGNKV
     ASTNIVTAPG IILSDTALDV NSPDIDIPTA VGGDDFLLNT FNEGNKISLP SVDAHDLINS
     VKDPLHASAG VDEQKLQLAG KSFYWGFGAL ALALVFIIGM VVGLHVSKRN CKPPSLHSSH
     RNQFNSNPQF GLKHGKDINL LMNPNHYCQT KKPNLDLEKD RSHECKNSTE NLEKELPCKT
     STLTKVKRTY I
//