ID   A0A1A9ZS86_GLOPL        Unreviewed;       639 AA.
AC   A0A1A9ZS86;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:GPAI023373-PA};
OS   Glossina pallidipes (Tsetse fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=7398 {ECO:0000313|EnsemblMetazoa:GPAI023373-PA, ECO:0000313|Proteomes:UP000092445};
RN   [1] {ECO:0000313|Proteomes:UP000092445}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000092445};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GPAI023373-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPAI023373-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- PATHWAY: Sulfur metabolism; sulfate assimilation.
CC       {ECO:0000256|ARBA:ARBA00005050}.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the sulfate
CC       adenylyltransferase family. {ECO:0000256|ARBA:ARBA00009290}.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the APS kinase
CC       family. {ECO:0000256|ARBA:ARBA00007268}.
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DR   AlphaFoldDB; A0A1A9ZS86; -.
DR   STRING; 7398.A0A1A9ZS86; -.
DR   EnsemblMetazoa; GPAI023373-RA; GPAI023373-PA; GPAI023373.
DR   VEuPathDB; VectorBase:GPAI023373; -.
DR   UniPathway; UPA00097; -.
DR   Proteomes; UP000092445; Unassembled WGS sequence.
DR   GO; GO:0004020; F:adenylylsulfate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004781; F:sulfate adenylyltransferase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0000103; P:sulfate assimilation; IEA:UniProtKB-UniPathway.
DR   CDD; cd02027; APSK; 1.
DR   CDD; cd00517; ATPS; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.10.400.10; Sulfate adenylyltransferase; 1.
DR   HAMAP; MF_00065; Adenylyl_sulf_kinase; 1.
DR   InterPro; IPR002891; APS_kinase.
DR   InterPro; IPR025980; ATP-Sase_PUA-like_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR024951; Sulfurylase_cat_dom.
DR   InterPro; IPR002650; Sulphate_adenylyltransferase.
DR   NCBIfam; TIGR00455; apsK; 1.
DR   NCBIfam; TIGR00339; sopT; 1.
DR   PANTHER; PTHR11055; BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE; 1.
DR   PANTHER; PTHR11055:SF1; PAPS SYNTHETASE, ISOFORM D; 1.
DR   Pfam; PF01583; APS_kinase; 1.
DR   Pfam; PF01747; ATP-sulfurylase; 1.
DR   Pfam; PF14306; PUA_2; 1.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF88697; PUA domain-like; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          240..397
FT                   /note="ATP-sulfurylase PUA-like"
FT                   /evidence="ECO:0000259|Pfam:PF14306"
FT   DOMAIN          406..632
FT                   /note="Sulphate adenylyltransferase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01747"
SQ   SEQUENCE   639 AA;  72503 MW;  A04D8A2712EA00AC CRC64;
     MLLNNNHNNN NVVIKCNLNH NTCNESCLQV ATNVTEQKHN VTREIRGRNL GLCRGFRGCT
     VWLTGLSGAG KTTIAFELEA YLVSRGIPAY GLDGDNIRTG LNKNLGFTPP DREENIRRVG
     EVAKLFADSG VVAICSFVSP FADDREMARK IHKDSDLKFY EIFVNTPLSV CESRDVKGLY
     KKAREGVIER FTGITQEYEE PKYPELIVST DGFTVKESTQ KVIDLLESEG IIPKTLKDVG
     KLPELFVKPE RKDAFIHEAK SLLSISITTV DLQWVEILAE GWAYPLKGFM REEEYLQTLH
     FNSILSHDGA SRHNQSIPIV LPLSKEDKEK LADQSSFALT YNNKLVAILR KPEFYHHRKE
     ERVCRQFGTS HPDHPYIKMI LESGDYLVGG NLEVLERIQW QDGLDEYRLT PNELRKKFKE
     MNADAVFAFQ LRNPIHNGHA LLMQDTKRQL LERGFEKPVL LLHPLGGWTK DDDVPLPIRM
     AQHQAVLDSG LLKREDTVLA IFPSPMMYAG PTEVQWHAKA RMNAGANFYI VGRDPAGMSH
     PDKQMYQDGN LYDGTHGSRV LKLAQGLDNL EILPFRVAAY DRSLACMAFF EPKRKENFEF
     ISGTKMRTLA KTGSNPPIGF MEPKAWQILA EYYKSVVQN
//