ID   A0A1A9ZTG7_GLOPL        Unreviewed;       702 AA.
AC   A0A1A9ZTG7;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=VWFA domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Glossina pallidipes (Tsetse fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=7398 {ECO:0000313|EnsemblMetazoa:GPAI024380-PA, ECO:0000313|Proteomes:UP000092445};
RN   [1] {ECO:0000313|Proteomes:UP000092445}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000092445};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GPAI024380-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPAI024380-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A1A9ZTG7; -.
DR   STRING; 7398.A0A1A9ZTG7; -.
DR   EnsemblMetazoa; GPAI024380-RA; GPAI024380-PA; GPAI024380.
DR   VEuPathDB; VectorBase:GPAI024380; -.
DR   Proteomes; UP000092445; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR013608; VWA_N.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR10166; VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED; 1.
DR   PANTHER; PTHR10166:SF37; VOLTAGE-DEPENDENT CALCIUM CHANNEL UNC-36; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF08399; VWA_N; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          77..180
FT                   /note="VWA N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08399"
FT   DOMAIN          351..446
FT                   /note="Cache"
FT                   /evidence="ECO:0000259|Pfam:PF02743"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   702 AA;  79831 MW;  415D0B388501C4EE CRC64;
     MSKANPPTKH TLAHMTPPPQ ETDILESGKG QSSFSPIYYE QAHPLPTEDD VETRIMDSAE
     QAALSELETQ GSHSATASNQ HYDARRINEY NADGKLADGA RHMDIRFMRR FERLPVNLSL
     SSILVPSGIS LNEDDVKAAL QWSSHLDPLF QNNLERDPAL SWQYFGSTAG FLRRFPGTAW
     PPEGSKGSKQ IHDFRTHNWF VQAVSSPKDI MILLDSSSSM SEKSFVLAIE TTFNILDTLG
     ENDYYNQSGE GSQCNQAIML ITESSSESHK EIIKQYNWPH MPVRIFTYLI GSDSGSRSNL
     HEMACSNKGF FVQINDISDA RRKVIDYALV MARPMIMYQA DHPMHWSPVF MAGKSGGLAR
     DSEYQRRLVT TVSTPVFDRR NHSVRVANLL GVVGTDVPVE EIRKMIPQHK LGPNGYSFIV
     DNNGRVLYHP DLRPLNDGNQ YIDQLRPKYT SVDITELELP ETEIGNDHEI VEMNKNLLYD
     MRSDMIIPKE GETEFTILQH FDDMKRVNAK TQRYFYGPIE DTPFTLAVVL PEKYGSHELV
     SQQEIRHSRK NVTEYFKGDN WRVHPDWVYC EYNSVSDLEK ERENSGEYTP RDQEPSFGSP
     EEQVLHFLAR AGRPGWKWMS VRPKPPQPHH NIHGATPVGH FGQHVNVQGS RKAEPYFCDR
     TLIQSLVRDA MVTDGLDRNS TVSPNGKEDK HPIATLLAIL KR
//