ID A0A1B0A0L2_GLOPL Unreviewed; 1644 AA.
AC A0A1B0A0L2;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Potassium channel domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Glossina pallidipes (Tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=7398 {ECO:0000313|EnsemblMetazoa:GPAI030774-PA, ECO:0000313|Proteomes:UP000092445};
RN [1] {ECO:0000313|Proteomes:UP000092445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000092445};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GPAI030774-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPAI030774-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EnsemblMetazoa; GPAI030774-RA; GPAI030774-PA; GPAI030774.
DR VEuPathDB; VectorBase:GPAI030774; -.
DR Proteomes; UP000092445; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR003929; K_chnl_BK_asu.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF10; SLOWPOKE 2, ISOFORM D; 1.
DR Pfam; PF03493; BK_channel_a; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 38..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 143..207
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 368..462
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT REGION 509..537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 723..771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1264..1291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1565..1644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..767
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1571..1644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1644 AA; 181678 MW; C04D47E055206188 CRC64;
MISNKSEFLA SAELTEEEFQ ENPIINWEAI LWVNRPTILW AVQLILALVS LTEAVLLTYL
GYKGNIWQQI LSFHFILELI TTIPFALTIL WPPLRNLFIP IFLNCWLAKR SLENMFNDLH
RAMQKSQSAL SQQLTILSAT LLCLVFTSVC GIQHFQRAGH RHLNLFQSTY YVVVTFSTVG
YGDFVPDIWP SQLYMVIMIC VALIVLPTQF EQLAFTWMER QKLGGSYSSH RAQSEKHVVV
CSTTLHADTI MDFLNEFYAH PLLQDYYVVL LSPMELDTTM RMILQVPIWA QRVIYIQGSC
LKDSDLARAR MNEAEACFIL AARNYADKTA ADEHTILRSW AVKDFAPNVP QYVQIFRPEH
KLHVKFAEHV VCEDEFKYAL LANNCTCPGA STLVTLLLHT SRGQEGQQSP EEWHRLYGKC
SGNEIYHIVL GDSRFFGEYE GKSFTYASFH SHRKYGVALV GVRPAELPEF YEDTILLNPG
PRHIMKKDDT CYYMSITKEE NSAFVVNQNQ QQQNSETNTP KETIKSTTST RVNSNNATTT
TTATTTTIIN TFSSITNTIT NTVSTSSTYL SMNMNVSSPV TPVPSVCVRV PHSPSYESGG
AETPILDSQQ YSNYEFTKLH VPTIPTTANA NPTSVIISDS KQNFKDTTVT STNATYTSAA
TTTTATTVPI NASLAMNLCG TSGPSFHSSL GNTLGIGMVT SITTGNHLDV PQAGNPNLLS
PDILNQRRGS RRPSILPVPD MFTSSSFSIT GNEDADEGDE SEDEVEDDVP WRSPSEKIAC
LGGHFPQSRT YSLIVSSSED SNLRDCCCNS STCRNSGSHT THTFSRHLQK MKKSYSCDSD
CARRSAIYES GYRIMAIPQM QANAMIPTTT GAVVILNGGQ QQLYDTCCSC STTSSVAPAS
TATAATFTTV SHHQRMTAQA TLSSSGSMQA TRPIWAADYS GIVKGFPPVS PFIGVSPTLC
YLLKEKKPLC CLQLAQVCEH CSYRNAKEYQ WQNKTIILAA DYASNGIYNF IIPLRAHFRS
KTSLNPIILL LERRPDVAFL DALSYFPLVY WMLGSIDCLD DLLRAGITLA ESVVVVNKEL
SNSAEEDSLA DCNTIVAVQT MFKFFPSIKS ITELSQSSNM RFMQFRAHDK YALHLSKMEK
AFVKDYVITF VRLLLGIDQA PGSGFLTSMR ITKDDMWIRT YGRLYQKLCS TTCEIPIGIY
RTQDTSNTET THVSNTPEEK WGPFSAFGKH CVRLRPSYEE DTTITPDSTK GSNEVLRSVT
YRPSAMSGPI SQQTSSHPTH HHNKSTTCLG GCTERKESSS TMYFQYSINL ADEARDNHAQ
QIERAEIANL VRSRMESLNL PTIDYDDVSE KRNHLSYVII NPSCDLKLEE GDIIYLVRPS
PFSAQKTFER HNSRRKSNIS FCSNINLSAA CGPTGISVAA AATGTGSRRG SGLGGLSPMQ
IQSIQTLAGY ASSRCTPPIQ QIKSNSLSLP DSPTVVGAQR SRSNSLRIEN DMLLRRSTSL
RQGLPNVGVS HGRRKSSLEE IGISHFTTLM QATNHTNPIK IALNGSIGLE NQISLQITPP
EEPTAILGVP SIAPNSGQSS GINPSSTGSS LAVNAPDLGN SANGDPNNSK NNNSSNVALQ
IPQDQQVQSQ SQSQSPQHLQ GTIV
//
