ID A0A1B0AGG3_GLOPL Unreviewed; 1403 AA.
AC A0A1B0AGG3;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};
OS Glossina pallidipes (Tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=7398 {ECO:0000313|EnsemblMetazoa:GPAI044953-PA, ECO:0000313|Proteomes:UP000092445};
RN [1] {ECO:0000313|Proteomes:UP000092445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000092445};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GPAI044953-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPAI044953-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- FUNCTION: Regulatory subunit of the condensin complex, a complex
CC required for conversion of interphase chromatin into mitotic-like
CC condense chromosomes. The condensin complex probably introduces
CC positive supercoils into relaxed DNA in the presence of type I
CC topoisomerases and converts nicked DNA into positive knotted forms in
CC the presence of type II topoisomerases.
CC {ECO:0000256|PIRNR:PIRNR017127}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CND1 (condensin subunit 1) family.
CC {ECO:0000256|ARBA:ARBA00009606, ECO:0000256|PIRNR:PIRNR017127}.
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DR STRING; 7398.A0A1B0AGG3; -.
DR EnsemblMetazoa; GPAI044953-RA; GPAI044953-PA; GPAI044953.
DR VEuPathDB; VectorBase:GPAI044953; -.
DR Proteomes; UP000092445; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026971; CND1/NCAPD3.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR007673; Condensin_cplx_su1.
DR InterPro; IPR024324; Condensin_cplx_su1_N.
DR PANTHER; PTHR14222; CONDENSIN; 1.
DR PANTHER; PTHR14222:SF2; CONDENSIN COMPLEX SUBUNIT 1; 1.
DR Pfam; PF12717; Cnd1; 1.
DR Pfam; PF12922; Cnd1_N; 1.
DR PIRSF; PIRSF017127; Condensin_D2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR017127};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR017127}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW ECO:0000256|PIRNR:PIRNR017127};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR017127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 76..239
FT /note="Condensin complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12922"
FT DOMAIN 1074..1234
FT /note="Condensin complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12717"
FT REGION 1302..1403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 443..477
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1302..1322
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1357..1371
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1382..1397
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1403 AA; 161645 MW; AE62E205FFA8D0E4 CRC64;
MDFQFNLPSS NTDLLNSSGD SYYVKHLYSS SEIPDKLKVC KQMLFQSDPF YIFDHFDTYY
AVIENKSTDA AAMKNLFRAF DLMYITVDKL GSSLAPILAA TEPLAPQQRK GYLNLTKMCL
FLLVNVVRKI DGNIVRLQQQ QQNSQQKRKS NKQLDTLEEY PDWDVKRGKF LVQLYNLMQC
PLQKLWNPPV AEENFVNMLC EVCYRTLEVL HMRNDNRHVV DTIFQIFGIA IKRYNHAINF
PVRILQILRS TEHAGRSIAY GINVLHEEFG ISTVFAVLIK EIIESLSMGS ADTLVSRYFS
NFLTELATIA PKLMIPHLST LGDELLGCES HVLRNCILQI MGDAVVGELT SEELPEDMKE
ARDEFLDNLL MHISDISAHV RAKVLQIWNH MKEEQAVPLS FQLKVLCAAV ERLEDKTCSV
RKQAVQLIKA FLERNPFSAK LTLVELQKKY NEEVEKMEKL SALLAAERKQ AEELEEKWNL
VIPKMLPFIE DIVKQTQDPP ETQETYEDLV QRINTMLLEE KYQEAVSLVR KADHVAGNSE
LRLSLKEEEQ CAYYLALLKS YIFLANGCKD SNEEFGTQIK TVKFLQDSIE FSKAISKAMP
KLQEMLLSKT NSDVFEAVDL FTTGYMFGIK GTENGMRQML YLVWSSDKEK RDAVSDAYKK
VLFTTDQTGR THALHVVQNL SRFLESLEYG HYTAMECLIK EWVHNEDIDS IIIQVLFERF
TLKLEGTTEN ESRLALQLLI MCSYAKSSIA SANISIIESI GLGLRGKQDP RIFSGCLEFL
LNSIDQSSTT KYYKRYEADY SIVQKVTEMY SKFFFHPRIP DFDQVTMKTL QFYYRLCQTP
DVISQTLVFE ILKQFKKVAV QLGEMTASQH AQALETPFSQ AIPGTQSHLT VAPQLKMPVF
LLTRFIFMIG YMALKEMIFL DIDVYNNMKY RQELTECEQK KKKSAFTNCN GNRRKTANLN
MSATESLKRL TGAAAEPQQE PDEDLVGATA EDNVAELINH ICEEILFHDE NALLPKLFPY
ILEICKYPFK YSDSALQQSA SLALVRFMCV SSRICESYMP FLMNILSHTK NIKIKCNIVI
GLSDLTFRFP NIIEPWTGHF YSTLHDENTE LRLTAVKMLS HLILHEMIRV KGQIADLAIC
IVDDNDEIKN ITQQFFKEIA NKSNILYNVL PDIISKLSDS SSNLEEEKYR IIMRYILGLI
HKDRQVETLV EKLCLRFPVT REERQWRDIA YCLSLLSYNE KTIKKLIDNL QHFKDKVQID
EVYQSFKLII SNTSKLAKPE LKTLIGELET RINDCLKIRE PTNEDEERNS ENDKETGRKL
RCLQKKSGKT STRSNNRRRR GKQDSSQSSS PHESSCSSSD FEDEPPKINK NKQQVRSKVI
QETASSDEEE SQIPRRKRGR NNK
//
