ID A0A1B0AH42_GLOPL Unreviewed; 692 AA.
AC A0A1B0AH42;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Acyl-coenzyme A oxidase {ECO:0000256|PIRNR:PIRNR000168};
OS Glossina pallidipes (Tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=7398 {ECO:0000313|EnsemblMetazoa:GPAI045574-PA, ECO:0000313|Proteomes:UP000092445};
RN [1] {ECO:0000313|Proteomes:UP000092445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000092445};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GPAI045574-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPAI045574-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the acyl-CoA oxidase family.
CC {ECO:0000256|ARBA:ARBA00006288, ECO:0000256|PIRNR:PIRNR000168}.
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DR AlphaFoldDB; A0A1B0AH42; -.
DR STRING; 7398.A0A1B0AH42; -.
DR EnsemblMetazoa; GPAI045574-RA; GPAI045574-PA; GPAI045574.
DR VEuPathDB; VectorBase:GPAI045574; -.
DR Proteomes; UP000092445; Unassembled WGS sequence.
DR GO; GO:0005777; C:peroxisome; IEA:InterPro.
DR GO; GO:0003997; F:acyl-CoA oxidase activity; IEA:InterPro.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IEA:InterPro.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 2.
DR InterPro; IPR006091; Acyl-CoA_Oxase/DH_mid-dom.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR012258; Acyl-CoA_oxidase.
DR InterPro; IPR002655; Acyl-CoA_oxidase_C.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009075; AcylCo_DH/oxidase_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR PANTHER; PTHR10909:SF223; ACYL-COENZYME A OXIDASE; 1.
DR PANTHER; PTHR10909; ELECTRON TRANSPORT OXIDOREDUCTASE; 1.
DR Pfam; PF01756; ACOX; 1.
DR Pfam; PF00441; Acyl-CoA_dh_1; 1.
DR Pfam; PF02770; Acyl-CoA_dh_M; 1.
DR PIRSF; PIRSF000168; Acyl-CoA_oxidase; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRNR:PIRNR000168};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|PIRNR:PIRNR000168}.
FT DOMAIN 155..265
FT /note="Acyl-CoA oxidase/dehydrogenase middle"
FT /evidence="ECO:0000259|Pfam:PF02770"
FT DOMAIN 299..463
FT /note="Acyl-CoA dehydrogenase/oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00441"
FT DOMAIN 508..689
FT /note="Acyl-CoA oxidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01756"
FT ACT_SITE 453
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000168-1"
FT BINDING 159
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000168-2"
FT BINDING 198
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000168-2"
SQ SEQUENCE 692 AA; 78340 MW; D609E6D5AA612C7A CRC64;
MAQNVDTSFI PDLPKGPLCA YRKRVNFDWK HLRLIFENEQ SLRIKYKVWK ILEHDPLFSQ
PISTLPTDEQ KRICAMQTNR MKQLDLVPKE IEEKSFCEKT KYLMSINEAL HVYCPSLSVK
IALGVGLFNN AIRAMGTERH KKYYEAAWHR EIVTCLAITE VSHGSNTKSI RTTATYDPTT
QEFVINTPDF EAAKCWVGNL GKSATVAMTF ANLHTPDGVN QGLHGFLIPI RDPNTLQPYP
GLLVGDIGEK IGLNGIDNGF VIFNNYRIPR ENLLNRTGDV TPEGIYESVF SEPGKVLGAA
LESFSAGRIG IMQESVNTLS SAAVIAVRYA ALRKQFGPER NGPEIPIIEY QYHQWRIFPY
LAAACVLKIA VQELTNEYLK IIERSQGDSN GFELLTQIVS EIHAIISSCK PMITWTARDA
IQEAREACGG HGYLKASKLG DLRNDHDPSC TYEGDNNVLG QQASNWLLRQ WTDNVESPVG
TANFLGNRKK LLQQKYEDVL EKDSIGSMNF IIRCYEWLMC YLLKTTSNRI SHDMQKGLNR
FDARNNAQVY GAGEVSLVYA EYFCMTRFIE RFKQPDITQE YSTILRLIFE VYSMWCLDKH
MTTYYVGGFA NSSKFADLVR TRLLSKCGEL KDISVSVADA LAPPDFALNS VIGKSDGLLY
ENLQNVFMTN EGAFERPAWW QDIVIPKMKS KL
//
