ID A0A1B0AHG7_GLOPL Unreviewed; 171 AA.
AC A0A1B0AHG7;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 22-FEB-2023, entry version 24.
DE RecName: Full=Bursicon {ECO:0000256|ARBA:ARBA00018035};
DE AltName: Full=Bursicon subunit alpha {ECO:0000256|ARBA:ARBA00029634};
OS Glossina pallidipes (Tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=7398 {ECO:0000313|EnsemblMetazoa:GPAI045899-PA, ECO:0000313|Proteomes:UP000092445};
RN [1] {ECO:0000313|Proteomes:UP000092445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000092445};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GPAI045899-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPAI045899-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBUNIT: Heterodimer of burs and pburs.
CC {ECO:0000256|ARBA:ARBA00011633}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00039}.
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DR AlphaFoldDB; A0A1B0AHG7; -.
DR STRING; 7398.A0A1B0AHG7; -.
DR EnsemblMetazoa; GPAI045899-RA; GPAI045899-PA; GPAI045899.
DR VEuPathDB; VectorBase:GPAI045899; -.
DR Proteomes; UP000092445; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR006207; Cys_knot_C.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR004133; DAN.
DR PANTHER; PTHR15283:SF7; BURSICON; 1.
DR PANTHER; PTHR15283; GREMLIN 1; 1.
DR Pfam; PF03045; DAN; 1.
DR PROSITE; PS01225; CTCK_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00039}; Hormone {ECO:0000256|ARBA:ARBA00022702};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..171
FT /note="Bursicon"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008403848"
FT DOMAIN 50..140
FT /note="CTCK"
FT /evidence="ECO:0000259|PROSITE:PS01225"
FT DISULFID 64..113
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00039"
SQ SEQUENCE 171 AA; 19195 MW; B6CEC255D5C8C3CA CRC64;
MFFKLENTKC ILFWNLVLFF FMARGIKDKV KAENAVLADE NDVSHIGDDC QVTPVIHVLQ
YPGCVPKPIP SFACVGRCAS YIQVSGSKIW QMERSCMCCQ ESGEREAAVS LFCPKAKHGE
RKFKKVLTKA PLECMCRPCT SIEESGIVPQ EIAGYSDEGP LNNHFRRIAL Q
//
