ID A0A1B0AKG6_9MUSC Unreviewed; 2663 AA.
AC A0A1B0AKG6;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=TOG domain-containing protein {ECO:0000259|SMART:SM01349};
OS Glossina palpalis gambiensis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=67801 {ECO:0000313|EnsemblMetazoa:GPPI000094-PA, ECO:0000313|Proteomes:UP000092460};
RN [1] {ECO:0000313|Proteomes:UP000092460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000092460};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GPPI000094-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPPI000094-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GCN1 family.
CC {ECO:0000256|ARBA:ARBA00007366}.
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DR EMBL; JXJN01025262; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 67801.A0A1B0AKG6; -.
DR EnsemblMetazoa; GPPI000094-RA; GPPI000094-PA; GPPI000094.
DR VEuPathDB; VectorBase:GPPI000094; -.
DR Proteomes; UP000092460; Unassembled WGS sequence.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:UniProt.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 7.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR23346:SF7; EIF-2-ALPHA KINASE ACTIVATOR GCN1; 1.
DR PANTHER; PTHR23346; TRANSLATIONAL ACTIVATOR GCN1-RELATED; 1.
DR Pfam; PF02985; HEAT; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 5.
DR PROSITE; PS50077; HEAT_REPEAT; 3.
PE 3: Inferred from homology;
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1356..1589
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 1530..1567
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 1649..1687
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 1997..2034
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REGION 820..845
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2663 AA; 296819 MW; E039FA73A3EB0CFE CRC64;
MKVIHFLYIR KIKKVRLQGM ANTETELSKI VRDLPNRAIN VAIEDRPALF KKTIGPMLMD
PAVNSAIIRG ICKTIGSTLT KYKDSASQQL VRGLITDLLK SHHDSAIENL MAVFKVLACK
ELPNAPAQKG SKAAIIALGW SILLNKHGDL NSNVFKTELP RLIEYQALLY HIVLLGSSAR
LIDMVDGVMF EIFESPVYFP QYLTVLIDKE PSGYVIVALM LLVKFKERVQ NESLLCEYKP
KLIDHFVKGI ITAKIKPSSD YIPACKLLLN SITKDEFEEK FLPPIQRAML RNPEIILQAV
ALIIHEINLD FSPYALQLGK ILLQNLYSKD ETARTESVDC LQKLSLKCTK PDVIAELLKN
IFSILNGSEG KITVAEYRMN LMQGAGNLSY NAVPIAQMSK ILFIATELFS KALLIEIHEK
VICHTLEMFS LWSVKMTGQL DQNITEIFQK GIQLKTTTPA VRLSYLQWLL AALHNGTLSK
ESKLTPMLST IFDKALQNPS QVALLSEATC AACIILKTEG TEADEKLTIF WNNVLDMSKS
IFFAERFVIT APPETLCYVI LIAECLLRNH FNNLRGDAYV LFRAIVRGIT SVSGKVRNYV
NNLLPKITRC TDGISFVRKI FMELEKFANS YDKDVENTEE NEIFASNFVE SIHTLCDFEK
LASADGQNLA LQSLVVCHHP LLVSGEDNLW ENVVRFQFDL DPKVFISLNA KQITEMIITN
FKPIKAYENA VATLIRLSPD VILPLLIGKV TTELKNPNMV NVSDDDYFTY LTPEGELYDK
SVIPNNEELY VTTGIKRENK VYSYKEQLEE LQLRREIEEK RRKEGRAKPP QLTPKQQEAI
RNQTEKENQI KKRLQALNAK LICIIKMIKS AGVGNAKQLS LHFPAILGAI LSAMKSPLSA
SLLSELYFEL RLACFDDCDL AFKVATTTIR LQMPRCDLKS EWIESDISEA TENTLHMLYN
NVIVEKNTLL APTFTYIFEF LKRALVAKKL VIDEELLLMG IKILEEHAQI RGDSLIGDIN
DYRHPKYMPR MEMFQLLLSF INNNQGRIQT QAVVTLLEVA QSSSGDDYCA IATREECRLF
LNTLEASLEA SRDVALRALK IMCRPLVEQS LLDEEMLRII TRRLWIARFD VSNENQHLAN
ELWKSVDLEQ PQFEDLLCDI IHPELNIQKA TAASLVPLLS EDPSLAKRTL KKLLTIYNEK
LTMIPPKLDQ FDREIESAID QWRPRRGVAI AIAQIAQFFS LEDVNHVMQF MVSTGLGDRE
EIVHKEMLAA ALTIVDLHGK EAIITLLPVF EEFLDKAPKS QSFDNIRQAV VILMGSLARH
LEKNDKRIEP IVKRLLAALS TPSQQVQEAV ANCLPHLMPS VKDEAPAMIK RLLQQLVKSD
KYGERRGAAY GIAGIVKGLG ILSLKQFDIM SKLTTYIQEK KNYKSREGAL FAFEVLCTTL
GRLFEPYVVH VLPHLLQCFG DSSQYVRQAA DECSKVVMGK LSAHGVKLVL PSLLEALDED
SWRTKTASVE LLGAMAFCAP KQLSSCLPSI VPKLIEVLGD SHTKVQEAGA DALKVIGSVI
KNPEIQAIVP VLLKALEDPS KNTSICLQSL LQTKFVHFID APSLALIMPV VQRAFMDRST
ETRKMAAQII GNMYSLTDQK DLTPYLPNII PGLKMSLLDP VPEVRAVSAR ALGAMVRGMG
ESSFEDLLPW LMQTLTSESS SVDRSGAAQG LSEVVGGLGV EKLHKLMPEI IATAERNDIA
PHVKDGYIMM FIYMPGAFPQ DFTPYIGQII NPILKALADE NEYVRDTALK AGQRIVNLYA
ETAVTLLLPE LERGLFDDNW RIRFSSVQLL GDLLYRISGV SGKMTTETAS EDDNFGTEQS
HTAIIRFLGH ERRNRVLSGL YMGRSDVSLM VRQAALHVWK VVVTNTPRTL REILPTLFGL
LLGCLASTSY DKRQVAARTL GDLVRKLGER VLPEIIPILE RGLNSEQADQ RQGVCIGLSE
IMASTSKEMV LTFVNSLVPT VRKALSDPLP EVREAAAKTF ESLHSTVGSR ALDDILPSML
EGLSDPDPEV AENTLDGLRQ VMSIKSRVVL PYLVPQLTAP PVNTKALSIL VSVAGEALTK
YLPKILCALL QALAEAQGTL NESQELEYCQ TVILSVSDEV GIRTVMDTLM TYAKSDDLIA
RKSSASLLSA FCMHTPGDYS QYVPQLLRCL LRLMAEQDRD ILQRSWDALN AVVKGLDSAQ
QIAHVSDVRQ AVRFAASDSK EAELPGFCLP KGITPLLPVF REAILNGLPE EKENAAQGLG
EIIALTSAQS LQPSVVHITG PLIRILGDRF NAGVKAAVLE TLAILLHKVG VMLKQFLPQL
QTTFLKALHD QNRTVRMKAG HALSELVIIH TRADPIFNEI HNSVKSSDDS AIRETMLQAL
RSVISPAGDK MTEPLKKQIY VTLIGMLGHS EDVTRSAVGG CLGALLKYLS TDQVDDILRH
HILIDDNDDS SLKHGRTVVI FVALKESATT ILNTAHHDSI LKVLITNISS DKVQIAGNGI
RGATYLIEYW MINKLLPAQP IVTAFTRAMN HNSNDIKQLV AKSCNHMAKT LEASQISPEI
MRYLIPMLVN GTKEKNGYVK SNSEIALISM LRLRDDETTY SKVCDILDAG ARDSLNEVVS
KVLRKAAIQP AGKDEEFDDT LLI
//
