ID A0A1B0ALF3_9MUSC Unreviewed; 784 AA.
AC A0A1B0ALF3;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=TGF-beta family profile domain-containing protein {ECO:0000259|PROSITE:PS51362};
OS Glossina palpalis gambiensis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=67801 {ECO:0000313|EnsemblMetazoa:GPPI000770-PA, ECO:0000313|Proteomes:UP000092460};
RN [1] {ECO:0000313|Proteomes:UP000092460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000092460};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GPPI000770-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPPI000770-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; JXJN01031002; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0ALF3; -.
DR STRING; 67801.A0A1B0ALF3; -.
DR EnsemblMetazoa; GPPI000770-RA; GPPI000770-PA; GPPI000770.
DR VEuPathDB; VectorBase:GPPI000770; -.
DR Proteomes; UP000092460; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd13751; TGF_beta_GDF8_like; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF291; LD29161P; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 675..784
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 322..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 446..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..478
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 784 AA; 90323 MW; 3F397FF037C60EC6 CRC64;
MCSNYKYFRR QEIQAEINEK NLIAAGNTIR NRRWSRINGN TNRHSNVVNN ALKTHYKIKN
ESLQASQHHQ SFNQTRSASL STSSTIQFND HKCNNRLFKC TKSIQSYKSL LKKWRPADNA
IRRSACSRSC QTKKRSLMYS TKTISSVNTK HVVASNKKRF HKFILKQFPK NSSSDLQIST
LLSKDTSVLP TSLRLFGRSM LEFYRSSSFF IVALIICLIL HSSCATTSQT TLPSKPTSSV
MPSDTFVVSQ VANSSSTRLQ GLTLALGIAE NSFYNNHTTI IPLVSTGDQL HSLIPKELTW
EIGSQDNNEN VISYINRHNI LNHRQHGQHQ QISTKQRRTE NESKNNINDE TIAYNQRKES
YNNSPQSDNF TSASSCYSCQ MRERAKLDNL ESIKRHILMR LHMSQLPNIT DPPVVPQIIL
ENFYKSFHTS KTSTPTTYNM RYPAHQDHSI GYKPSASVKS NYDEDGNNHG EGDEPINFDN
KMQGDSPQRL YNIFNYNSEE ESYDEFYSHL HSIFIFPTIT RLRHNHKPEV LNFNLHCDAS
NIGRAFLHVY IRGHNWMRER HPELLEYKHS DGRTEQRREV IISVHRALRR PNSVNYTHTV
KLIEVKCKIP MGFGQWTEIE MKQLSMYWSA NGNATQSLII NGNESWMRPF IVTDSKTSNR
ALRIHIELMT KAPKRNKRSA SLDCREGDNE VRCCRYPLRV NFKELNWTFI MAPGYFDAYF
CNGNCKAGYL EQYTHTHLTT LSTSATPCCA PSKMSPLPLL YFTAHEELLM TVIPNMSVDK
CSCF
//
