ID   A0A1B0ALW2_9MUSC        Unreviewed;       590 AA.
AC   A0A1B0ALW2;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=Protein krueppel {ECO:0008006|Google:ProtNLM};
OS   Glossina palpalis gambiensis.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=67801 {ECO:0000313|EnsemblMetazoa:GPPI001201-PA, ECO:0000313|Proteomes:UP000092460};
RN   [1] {ECO:0000313|Proteomes:UP000092460}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000092460};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GPPI001201-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPPI001201-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; JXJN01000168; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A1B0ALW2; -.
DR   STRING; 67801.A0A1B0ALW2; -.
DR   EnsemblMetazoa; GPPI001201-RA; GPPI001201-PA; GPPI001201.
DR   VEuPathDB; VectorBase:GPPI001201; -.
DR   Proteomes; UP000092460; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.1800.20; -; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 9.
DR   InterPro; IPR012934; Znf_AD.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR24393:SF34; FEZ FAMILY ZINC FINGER PROTEIN ERM; 1.
DR   PANTHER; PTHR24393; ZINC FINGER PROTEIN; 1.
DR   Pfam; PF07776; zf-AD; 1.
DR   Pfam; PF00096; zf-C2H2; 5.
DR   Pfam; PF13912; zf-C2H2_6; 1.
DR   SMART; SM00868; zf-AD; 2.
DR   SMART; SM00355; ZnF_C2H2; 9.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR   PROSITE; PS51915; ZAD; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 9.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 9.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU01263};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU01263};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   DOMAIN          11..114
FT                   /note="ZAD"
FT                   /evidence="ECO:0000259|PROSITE:PS51915"
FT   DOMAIN          249..276
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          327..349
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          367..394
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          395..422
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          423..450
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          451..478
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          479..506
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          507..534
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          535..562
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   REGION          268..294
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          302..321
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         13
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT   BINDING         16
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT   BINDING         87
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT   BINDING         90
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
SQ   SEQUENCE   590 AA;  68280 MW;  61F665A154FF6098 CRC64;
     MDNSTATKLQ TVCRTCMSSE ANAESSETPP YKKRKTFKTS TSNMISIYNS PEGTDNNVNS
     PPIIDMLLNT TPQLRIEAND DLPKYVCEQC VGKLLKAYEF QQMSLRVDQQ LREMLQEQKH
     LPNENVEGKE DSVDISMDDP LDDSISRAIC DITTTIKIEM EEPLIDTTQL ENNYAERNTS
     TENIKYEMQV QEYELSDEVE GDDRNCDSDD SDWVLEEYRR QQQQLNINKL REKDIKITST
     AKISIPKDFV CDVCGNALST SKSLKRHKKI HLRGKGSQPI PNTNGEKLPK VEGDGDEIMS
     VEKENEEEHV EEKPQVESND EEGKKRFICD VCGGRLSTRK SLKRHEKIHM RGPDEIKRRP
     IGQKATYECK YCQKVFQQSS TLKDHLRVHT GEQPFLCSEC GKAFKSLSNM KQHLLRHNAD
     KRYECPDCPK KFPCLSDLAS HKAVHYKNKA HVCDMCGAGF IKPYQLKKHK MYHNGEKPHK
     CEYCEMRFVL ADQMRRHMRT HTGEKPYKCK YCTRAFAQSN DLVKHLRSHL GDNVYKCELC
     PQGFRLIKDL RVHFATHKNE DEETRKRNLQ ALLEEEKKLQ MKFGLTEISM
//