ID   A0A1B0AT06_9MUSC        Unreviewed;       914 AA.
AC   A0A1B0AT06;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=TFIIS N-terminal domain-containing protein {ECO:0000259|PROSITE:PS51319};
OS   Glossina palpalis gambiensis.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=67801 {ECO:0000313|EnsemblMetazoa:GPPI007538-PA, ECO:0000313|Proteomes:UP000092460};
RN   [1] {ECO:0000313|Proteomes:UP000092460}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000092460};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GPPI007538-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPPI007538-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649}.
CC   -!- SIMILARITY: Belongs to the IWS1 family.
CC       {ECO:0000256|ARBA:ARBA00037992}.
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DR   EMBL; JXJN01003090; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A1B0AT06; -.
DR   STRING; 67801.A0A1B0AT06; -.
DR   EnsemblMetazoa; GPPI007538-RA; GPPI007538-PA; GPPI007538.
DR   VEuPathDB; VectorBase:GPPI007538; -.
DR   Proteomes; UP000092460; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR   InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR   InterPro; IPR017923; TFIIS_N.
DR   PANTHER; PTHR46010; PROTEIN IWS1 HOMOLOG; 1.
DR   PANTHER; PTHR46010:SF1; PROTEIN IWS1 HOMOLOG; 1.
DR   Pfam; PF08711; Med26; 1.
DR   PROSITE; PS51319; TFIIS_N; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00649}.
FT   DOMAIN          708..786
FT                   /note="TFIIS N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51319"
FT   REGION          1..617
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          795..851
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        71..108
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        109..126
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        164..203
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        204..220
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        233..255
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        256..285
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        297..313
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        314..348
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        390..475
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        506..521
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        547..578
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        795..822
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   914 AA;  102816 MW;  F0F96C2D52A46BC1 CRC64;
     MPAVENGAVG YEDELRKDKS QNQEPLIPSL EEKTLKSRHR SRSVSPGNVS AELRHSKSRS
     RSGSRSSEGE PPSPRAEKEK QRFRSRSRSV SLDSDGRIKE RNESPRSDSR SPSRSSNISS
     EKPGLSKETK LPSRSRSRSS SRSSSESSRG QRELSKSRSR SRSHSSNARS ISPNVLTNQQ
     EKTNSRSLND EPYTPILSTK EKSDSVNISH DEDAGLKARR RSRSPSQCSL GFNKDDEPKR
     KSRSRSKEHT RGTPRSRSCS KSPSGIPSPS GKTPNDSVAR SRSGSRRSRS GSKRNNSRSR
     SRSISPLSRP ASRHRSRSYS KSASRSRSRS SRNRSRSGSK HSRSASKLSR SSRRSYSGSK
     HSRSGSERSR SGSRRSYSGS SDSRRSRSGS RRSRSGSRRS RSGSRRSRSG SRRSRSGSRR
     SRSGSRRSRS GSRRSRSGSR RSRSGSRRSR SGLRRSRSGS RRSKSGSRHS RSGSRRSRAS
     GSASRSRSRN SSRKSRSRSV RSHSKSADSR SGSLARSVSR SSRSHSRSRS KSHHSSISPT
     SKGQKGHKRN ILSDSEGEDG PSSAQKKRPK ITDTDNEDEA DKSEHEIVEE GGAQAASKNI
     GDSSDDENLP IDNDREPDNF ISDFDAMLLR KKEEKRIRRR KRDIDLINDN DDLIDQLIMN
     MKNASDEDRQ LNVEGKPATK KISMLKQVMS QLIKKDLQLA FLEHNILNVL TDWLAPLPNK
     SLPCLQIRES ILKLLSDFPT IEKSYLKQSG IGKAVMYLYK HPKETKQNRD RAGRLISEWA
     RPIFNLSCDF KALTKEERQE RDMRQVPKSR RKSPEPEPST SKKKRGLNSA FGNTEEKPLR
     PGDPGWVARA RVPRPSNKDY LIRPKSKIDG EVSTTNKRKP NRYEKHMKKF LDAKRLKSSR
     RAVEISIEGR KMAL
//