ID   A0A1B0B200_9MUSC        Unreviewed;      1157 AA.
AC   A0A1B0B200;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Kinesin motor domain-containing protein {ECO:0000259|PROSITE:PS50067};
OS   Glossina palpalis gambiensis.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=67801 {ECO:0000313|EnsemblMetazoa:GPPI016264-PA, ECO:0000313|Proteomes:UP000092460};
RN   [1] {ECO:0000313|Proteomes:UP000092460}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000092460};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GPPI016264-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPPI016264-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR   EMBL; JXJN01007391; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A1B0B200; -.
DR   STRING; 67801.A0A1B0B200; -.
DR   EnsemblMetazoa; GPPI016264-RA; GPPI016264-PA; GPPI016264.
DR   VEuPathDB; VectorBase:GPPI016264; -.
DR   Proteomes; UP000092460; Unassembled WGS sequence.
DR   GO; GO:0015630; C:microtubule cytoskeleton; IEA:UniProt.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 3.40.850.10; Kinesin motor domain; 2.
DR   InterPro; IPR027640; Kinesin-like_fam.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47969; CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED; 1.
DR   PANTHER; PTHR47969:SF15; ZGC:66125; 1.
DR   Pfam; PF00225; Kinesin; 2.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00283}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00283}.
FT   DOMAIN          4..350
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000259|PROSITE:PS50067"
FT   REGION          452..491
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          536..567
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1096..1119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          630..837
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          924..951
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        469..491
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        536..554
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         130..137
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ   SEQUENCE   1157 AA;  132062 MW;  E6E43898A28FD881 CRC64;
     MEIPVQVAVR ICPILPKEKP NTILNVDEAK NEGVQEDTAF LPKPDDDAPE EEKETKCCVK
     AINLTTNTAP VFLENGIGMV TGLIQVGPHS FPVTHALQPH CGQNEIYHQT IFPLVSLFME
     GFDASVVTYG QRNVGKTYAL YGHGFDCGYS EADQGVVQRC AREIFAHIAN HPERTYVVNI
     GWVEICGEVI RDLLGVGNVH CVSLTDVFHW LQVGLNTLNA SRREMAHSLF TLTLEQQWVS
     KEGLMQHRLS TASFSDLAAT ERLFMLNALE QPSSLPKDLG LQSLEQVVNA LTDPGANRNI
     PYNQTTLTTL LKDSFGGRAQ TLVMLCVSPF ERDVNETLCN LQFAFKVQCV RNYVVMNTFS
     DDNTPITPES LLPDIASGVT NALQPQIQEQ IGLQFAASQW FKLVANAEGL LSKLITSYNL
     AELDKEQIEE WLFLKQECEE CLSSNEIMRS SQKQLGPIQE AEEPDEAISE PETCQHNESD
     NESDSESQRP DLEEKLETLM EELSISTDRL VKERYQEFME THPRAVMESQ ESLKTIKKEA
     KHSDVEERKP SIGGRRRSLQ PGTTLSSAEI AMLNQVASRE RQDLKQKQND EFLDSSTEVP
     LRTHSNAPLE HIQKKVRKLD IDIEARLRQI KEVEETMQLK QNIIMELVKN SDTRSTAKQK
     FHKKRAKLEA EYEKTKKSLT KAMVNGKDKQ ECERLKAIMQ HLEQRLKDVT SIKHIAGESG
     QKIKKLQQSL QESKKMIEEL QKKVKKDRKL KQALENELKN LKEKENSKGL LKLEVANQTP
     EEKGKHLKEM QARISHLDHV LREKSENLEQ YGDDEQRETL RHEIRNLRRT RDHLLDQRCS
     LDRKLKRDKN LTQKEERKLL ECDEAIEAID AAIEFKNELI CGHKSIDTSD RLQREKGEQM
     LMARLNKLSL EEMRTMLYKY FNKVIDLRDS SRKLELQILQ LEREKDAWEW KERVLSNAVR
     QARLEGERNT VLLQRQHEIQ KALILRHLVE ETANSSTSFT DSQVNLGVLR NNNISLAANN
     SNGAIYSDTD SMINHKMFKS SKMAEMEMCP LNDNGLSKYK PLDKFKEKGR ETKNKLFKFQ
     VLTRYASAGQ NESGVNPIAS SSLNSDDGAN YKGRKDKETS AIAIPQENLK KLAINTNSTK
     VTRQKNKIII HDNSRKN
//