ID A0A1B0B9B5_9MUSC Unreviewed; 462 AA.
AC A0A1B0B9B5;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=KASH domain-containing protein {ECO:0000259|PROSITE:PS51049};
OS Glossina palpalis gambiensis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=67801 {ECO:0000313|EnsemblMetazoa:GPPI022926-PA, ECO:0000313|Proteomes:UP000092460};
RN [1] {ECO:0000313|Proteomes:UP000092460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000092460};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GPPI022926-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPPI022926-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the nesprin family.
CC {ECO:0000256|ARBA:ARBA00008619}.
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DR EMBL; JXJN01010341; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0B9B5; -.
DR STRING; 67801.A0A1B0B9B5; -.
DR EnsemblMetazoa; GPPI022926-RA; GPPI022926-PA; GPPI022926.
DR VEuPathDB; VectorBase:GPPI022926; -.
DR Proteomes; UP000092460; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0005635; C:nuclear envelope; IEA:UniProt.
DR InterPro; IPR039906; Anc-1/SYNE1/2-like.
DR InterPro; IPR012315; KASH.
DR PANTHER; PTHR21524:SF5; KLARSICHT PROTEIN; 1.
DR PANTHER; PTHR21524; SPECTRIN REPEAT CONTAINING NUCLEAR ENVELOPE PROTEIN 2; 1.
DR Pfam; PF10541; KASH; 1.
DR SMART; SM01249; KASH; 1.
DR PROSITE; PS51049; KASH; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00385}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00385}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT TOPO_DOM 1..415
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT TOPO_DOM 437..462
FT /note="Perinuclear space"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT DOMAIN 407..462
FT /note="KASH"
FT /evidence="ECO:0000259|PROSITE:PS51049"
FT REGION 329..404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 102..129
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 275..302
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 332..359
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 367..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..396
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 462 AA; 51563 MW; FAF5FD4E33FCCEA6 CRC64;
MKTISFRAHL LAAWEELLGW SENAVTPCKI QKELSDLKNA LNCMCNKSSS ELLDTEPDLH
IAIENLEKEE GQLQMYRGKM LKLNASAHSW LTKQEKRLSN ALEEQQLKEA AAKVNNNELI
EEKEEIESEQ QLTISKQLEV LKSSSTALSQ LESGLSEFKK ALVQDRSTLQ GLEGALKKGQ
PTPDDLENVK LVAKLLSEKV NVSQEQLSAV QGYLDSNQIL HFTRFTASNG SLSDSGISDG
GTTSDGGLSE HERHLGFLRR LAKQVESLAP GSEAMKSIAA RVEAAEAELK NFQNTCRALI
VRTVVSQQNK QQQHESNNGI KLNGMKLTEK VRQSSQHIDQ EKRRSNDLHG SDNGRRSRRR
LRCLPGNNSH IRQNNGLQTT PDDDDPSDDP SLTYEIDSSD DDQAPKRGWA WRIARVAVPM
QLALFTVFCA ACLMQPNCCD NINNFSMSFT PQLRYIRGPP PI
//
