ID   A0A1B0BB53_9MUSC        Unreviewed;      1046 AA.
AC   A0A1B0BB53;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=NFACT RNA-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Glossina palpalis gambiensis.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=67801 {ECO:0000313|EnsemblMetazoa:GPPI024499-PA, ECO:0000313|Proteomes:UP000092460};
RN   [1] {ECO:0000313|Proteomes:UP000092460}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000092460};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GPPI024499-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPPI024499-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the NEMF family.
CC       {ECO:0000256|ARBA:ARBA00008318}.
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DR   EMBL; JXJN01011305; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A1B0BB53; -.
DR   STRING; 67801.A0A1B0BB53; -.
DR   EnsemblMetazoa; GPPI024499-RA; GPPI024499-PA; GPPI024499.
DR   VEuPathDB; VectorBase:GPPI024499; -.
DR   Proteomes; UP000092460; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0072344; P:rescue of stalled ribosome; IEA:UniProt.
DR   Gene3D; 2.30.310.10; ibrinogen binding protein from staphylococcus aureus domain; 1.
DR   InterPro; IPR021846; NFACT-C.
DR   InterPro; IPR008532; NFACT_RNA-bd.
DR   PANTHER; PTHR15239; NUCLEAR EXPORT MEDIATOR FACTOR NEMF; 1.
DR   PANTHER; PTHR15239:SF6; RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF; 1.
DR   Pfam; PF11923; NFACT-C; 1.
DR   Pfam; PF05670; NFACT-R_1; 1.
DR   Pfam; PF05833; NFACT_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   DOMAIN          539..649
FT                   /note="NFACT RNA-binding"
FT                   /evidence="ECO:0000259|Pfam:PF05670"
FT   DOMAIN          947..1036
FT                   /note="NFACT protein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11923"
FT   REGION          679..700
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          715..754
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          811..884
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          336..373
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          494..521
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        723..739
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        841..863
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1046 AA;  119213 MW;  DF37701A1BE045C0 CRC64;
     MKLRFNTYDI VCGVAELQKL VGLRVNQIYD IDNKTYLIRL QGSEHKTILL IESGIRFHTT
     AFEWPKNVAP SGFSMKLRKH LKNKRLEKLQ QLGVDRIVDF QFGMNEAAYH VIVELYDRRN
     IILTDHEFTI LYILRPHHEG QDLRFAVREK YPLERAKQGK TLPTKEQLQG IINEAEGGNS
     LRYILMPLVD CGPTVIEHVL IKHKLDNCVT PSSHISNESA ELCIKEESQK KAKKKNKREA
     KKRADCRLFE PELDLDAVMV ALEEAFELLA KARSLVSQGY IIQKKEEKPA IEGSSKLEHF
     YQNIEYQPYL FKQYEGQPVA IFESFMLAVD EFYSTLEGQK IDMKTLQQER EALKKLSNVK
     KDHAKRLEEL NKIQEHDKRK AELISCNQAL VDNAILAIRS AIANQMSWPD IQELVKAAQT
     NADPVAGAIH QLKLEINHIS LKLSDPYAVS SEDSDDYGES GIKKEKDVMV VDVDLGLSAW
     ANARKYYDLK RSAAQKEQKT VDASQKALKS AERKTQQTLK EVRTISNISK ARKVYWFEKF
     YWFISSENYL VIGGRDAQQN ELIVKRYMRP TDIYVHAEIQ GASSVIVRNP AGGEVPPKTL
     LEAGTMAISY SVAWDAKVVT NAYWVHSDQV SKTAPTGEFL GTGSFMIRGK KNFLPSCHLI
     MGLSLLFKLE ESFVERHRGE RKVRSFDEEQ QEDEQEAKTH ILENEQLDSI YEVEEELNTE
     DSGNGETKIS EAAQTPKSSI SEEIEEEDDK SSANDIAVKK TFEFPDTQVK VEHDTGKIII
     EKSKVTENEL TSTKVALKNL NMSVKLFEEK EEATIISSVP THKKRQQNAR KRKEEKAYNS
     QKNQKQQQQV SSIDNSNAKS AMQFKRGQKG KLKKMKAKYK DQDEEERQLR MQILKSAGNI
     KTLETDAKFD EKTDSSKPLN KVQRQVEPKL VTDADGEEAD DLLTGADVEM LDALTGLPFE
     EDELLFCIPV VAPYQALQNY KYKVKLTPGT GKRGRAAKTA LTMFSKDKLC SVREKDLLKS
     IKEEALARNI PGKVKLSAPQ LQKYRK
//