ID   A0A1B0BKM2_9MUSC        Unreviewed;      1542 AA.
AC   A0A1B0BKM2;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   22-FEB-2023, entry version 23.
DE   RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
OS   Glossina palpalis gambiensis.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC   Glossinidae; Glossina.
OX   NCBI_TaxID=67801 {ECO:0000313|EnsemblMetazoa:GPPI033161-PA, ECO:0000313|Proteomes:UP000092460};
RN   [1] {ECO:0000313|Proteomes:UP000092460}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAEA {ECO:0000313|Proteomes:UP000092460};
RA   Aksoy S., Warren W., Wilson R.K.;
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:GPPI033161-PA}
RP   IDENTIFICATION.
RC   STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPPI033161-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   EMBL; JXJN01015975; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 67801.A0A1B0BKM2; -.
DR   EnsemblMetazoa; GPPI033161-RA; GPPI033161-PA; GPPI033161.
DR   VEuPathDB; VectorBase:GPPI033161; -.
DR   Proteomes; UP000092460; Unassembled WGS sequence.
DR   CDD; cd13309; PH_SKIP; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR46556; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2; 1.
DR   PANTHER; PTHR46556:SF1; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
FT   DOMAIN          1172..1275
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          208..237
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          457..555
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          654..682
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        487..501
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        503..521
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        536..550
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1542 AA;  170755 MW;  0EC9CD17D344AB6D CRC64;
     MESPLFAAKS MESKLSTTPG SLKRVDLNTS ISAANVNNAD KMSASIQSGT LDDTTPSDSG
     VQMLDSESSE LMIDSITSQT GFEFEDAKCI TIAIEKTKSS STVGAPEEAA VVDSNFNVTA
     ISAVSAGVEE AMTTSQISTF GDTTENIVYR RKVRKTPAVA KAPKKRVSFH EDILKNTRTD
     NIHIEHGFIT YKAGIRKMNQ QVSGAGRYSW CSEGDKTEPT ELPQNGDEDT QGGDAANGRR
     RIVYRNACSD VLDYGNSDVY DMNDDNCLQY DNSGVFEYTT ATDNNVAKLA TALNAKKNLN
     PELYKCSCSS SNSSLDSDEN DKNSNCHQYE QAKSSSCDCI GVSNNNNNFI GENCYYSEPN
     IGSNNSPPRQ KSVWNKEKKP KSSCLKKTKF HTDVIQEQDL SNKVKKFNVH DVNQLLDNSS
     KMIFGSLKSI FTMPLPERGV PEGSEDLQAV IECVPEPEQT PEHQKNEFNA KQIPDSPPLK
     TKPFLSKSLD GSKQQQPVKK FVHNVDEQLR RRNEEEMYAP TRDNSSESQL KETEHSNTPQ
     LKRQNEFDND NDNDMSSLVT DSLAAVDNTP FRNKFIINCE STVFEHTGVS YSYESSSSSF
     NDLICMEDSC GNIADLIEKD TPFAQPEPDQ LRNAFMSAPI AKTFSNFFRS FKDTGKDKSS
     AKGIKPNNRE TEAKHKIQDQ EAKEWQEATD NYFALKMPRK WETNAQSLST STPYKVPKIS
     STISDISSIM DNTSSTNMAQ LVQQTTKSNS SLTSGIASGS VSTSGSCNQR ESLAIGCDLR
     VNLEKQSRHI PSPLKKRLSA SGSNLIQQNA PQRYGVSAPQ PDPTLLSPDL FSHYNIARGG
     SGRDSKSTIL SEEFDDILTV TTDTDKNESD IIIVDYPEVS DRQSSADYAN LLKPPQPPAK
     TSLINRFLRN VTQKKILESS IKRNNFFAHK LKTGQKLFTG NLYVKGARPR NIELIEDLNA
     EIAMEIEMSG VNSPRRELTN LESDLPGDLS RFELGIGEIS VDVFIGSNLN FLLNASEILM
     KAFKLYTGYS KEGYMTPVLV FLTDKTLYVT DLVRNRLCSK FILAYKDLDV ILTGPYGNTV
     LLSNSTRDMQ QVLLAGGPYS ADSLVANLEL CARRHGSILP AVGQLTLNHL VPLQDFVRAN
     SCVGKSDSWM YYAVVNMPGS SLGEGGEQEP LGPHAKGFLM HRRTRDHIST SKHQLWNPGY
     FLLKAGVLYM FNDSTQKIPS WAMALAECQG ARRAVKAGRP HCFEIMLKDK MLLQLAAPDE
     YVASEWLQAL LQSASGLFEM QEKHKTLGCT LVVTQNHLIT LREDFSAPLK QFNKKIESIA
     HEGIMNSAAA ITNTKFEEEL PHFMPDTGSL LSSAMSTPTR GTLRSCSSIN STPTKLSQFS
     RSTTTFNTTL GSSLASNATT NSTISTATFS KQAQVETKEG QISMNSVYGK NSGLEILTCA
     DIKEMIGIKI PSHNDTWWCV LEFSCQEVRE CSDDLVIFFA SSAEMQRFLR LLEQLWQAKN
     NDLFPITVLD EDDLVAEQCT TLYMEINRSW EPLLSAALGY PL
//