ID A0A1B0BMJ7_9MUSC Unreviewed; 660 AA.
AC A0A1B0BMJ7;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=BHLH domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Glossina palpalis gambiensis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=67801 {ECO:0000313|EnsemblMetazoa:GPPI034851-PA, ECO:0000313|Proteomes:UP000092460};
RN [1] {ECO:0000313|Proteomes:UP000092460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000092460};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GPPI034851-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPPI034851-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JXJN01016979; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0BMJ7; -.
DR STRING; 67801.A0A1B0BMJ7; -.
DR EnsemblMetazoa; GPPI034851-RA; GPPI034851-PA; GPPI034851.
DR VEuPathDB; VectorBase:GPPI034851; -.
DR Proteomes; UP000092460; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd11440; bHLH-O_Cwo_like; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR003650; Orange_dom.
DR PANTHER; PTHR10985; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED; 1.
DR PANTHER; PTHR10985:SF141; TRANSCRIPTION FACTOR CWO; 1.
DR Pfam; PF07527; Hairy_orange; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00511; ORANGE; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF158457; Orange domain-like; 1.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS51054; ORANGE; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT DOMAIN 98..153
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 164..195
FT /note="Orange"
FT /evidence="ECO:0000259|PROSITE:PS51054"
FT REGION 274..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 433..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..364
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..387
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..468
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 660 AA; 74062 MW; 985744FDC8B13126 CRC64;
MDRQHWVVVI VFSFISFSIK TTNKNNYYYY YYYYYYYYLL PTTTPSTTTY NNKYYSEAAV
SSFPYCTESS LNFSTNATGY SEDDAEYANG RRNKTSRQDP LSHRIIEKRR RDRMNSCLAD
LSRLIPPQYQ RKGRGRIEKT EIIEMAIRHL KHLQSECLQK ENEYRMGYTD CMKETAKFLY
DSQMQEFCYR LLARLQEHCD EIMKSECFRS RSCHVADNVS ASSGSPHQSF HTAPPLCQLR
DILGASDIEH SNDHNDVKDL SFRNHLHQLQ RNAGTLNGNS ATDQHHHTGP TNHNTNSVSS
NATTISPPMM TSNTATSSTN STVNNGSATS QLPHQTPIIT STATTSLHHH TDSSNHDFDS
SREPMLHTDT SNMHSPPPRS TLLTLHSHQH LSHHHDNLLQ GRLRNFSESS HDVEHNNNYK
YKNHIKERFN HELHDEETSS EHCPAPPLLQ SDHSHAHSEH SKDGTEPEIA PIIAKKRKLA
EAANNHNEAT MDESNLRIAS KGGCTNNAVL LTNIGREEKP FAAFSEIKTE TIPAGFLTNN
KGHLNAPTST TTPLPTRSFA VPIFALHSQG TYYVPLNVDY NVLVPFLNGV DLLEKNYATM
PVVHPININV NFVPSSSSSS SSTSLLAAAA AAAAVAAGKQ QPPLNTAKGK LEAITNSNGW
//
