ID A0A1B0BRT5_9MUSC Unreviewed; 756 AA.
AC A0A1B0BRT5;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
OS Glossina palpalis gambiensis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=67801 {ECO:0000313|EnsemblMetazoa:GPPI038558-PA, ECO:0000313|Proteomes:UP000092460};
RN [1] {ECO:0000313|Proteomes:UP000092460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000092460};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GPPI038558-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPPI038558-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; JXJN01019311; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0BRT5; -.
DR STRING; 67801.A0A1B0BRT5; -.
DR EnsemblMetazoa; GPPI038558-RA; GPPI038558-PA; GPPI038558.
DR VEuPathDB; VectorBase:GPPI038558; -.
DR Proteomes; UP000092460; Unassembled WGS sequence.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF168; CULLIN-3; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 374..622
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 756 AA; 87452 MW; 066056FAF8173CFE CRC64;
METGGVAYEN IIKNDDTVDL MCARLKDAVA QIQNKNTADL SFEELYRYAF LMIYKQGGQR
LYNDLHATIE EHLEKNVRQD VLKSLPNDLL SKLSHVWIDY QTALKFICNI FAYMDRVFIA
RNKGYESVYN LGLIAFGDKI ICYAEIQKSL SDILLNLIND ERDGKVVDRA ALKNACEMLM
TLSINSISIY KDVFEQHFLD QSSLFYKLES QKLLAENNVN NYVKTTTARI QEESDRASFC
FDKSTEKSIL NIVEDELLKK HLHAIVAMEK CTVGHMIKNK MTKDLACMYK LFSRLKEEGI
KVIIETMSSC FRVYGRSLVR DVVDDKMNGV TFVQNLINLK DDMDALLKYS FKRNKTIKKS
LLADLGYILH LNAKSPEYIS LFIDDKMKKG GKEMEEKEIT KVLDKTIEIF LLLKERDVFE
AHYRRHLSKR LLLSRSDSED IERIMISKLT IACGHEFTKN FQRMIKDLSL STSINAEFKS
YVSKDSVSLC GVDLTVDVLT SGFWPTTTSS EIKCNIAAEP FKAFEIFKNF FLTTRARRKL
TLQPHMGSAL ISAEFYGPQV ESDRYESEAI LKTKHKYILV ASTYQMCILM LFNDYNVMSC
EEIQKKTDLP ESELHAALQS LSMGKLSQRI LVRKSQTNLK DIAATDKFFV NEEFISKFYR
VKIQSTVAKE NSESERKKIN DNLDLQRKYE IKAAIVRIMK ARRSMDHNLL ISELTHQLKS
RFLPSPVMIK KQIEILIDKE YIARETDNLK RYIYLA
//
