ID A0A1B0BS37_9MUSC Unreviewed; 347 AA.
AC A0A1B0BS37;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=small monomeric GTPase {ECO:0000256|ARBA:ARBA00011984};
DE EC=3.6.5.2 {ECO:0000256|ARBA:ARBA00011984};
OS Glossina palpalis gambiensis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=67801 {ECO:0000313|EnsemblMetazoa:GPPI038848-PA, ECO:0000313|Proteomes:UP000092460};
RN [1] {ECO:0000313|Proteomes:UP000092460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000092460};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GPPI038848-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPPI038848-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; EC=3.6.5.2;
CC Evidence={ECO:0000256|ARBA:ARBA00023421};
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Ras family.
CC {ECO:0000256|ARBA:ARBA00008344}.
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DR EMBL; JXJN01019455; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0BS37; -.
DR STRING; 67801.A0A1B0BS37; -.
DR EnsemblMetazoa; GPPI038848-RA; GPPI038848-PA; GPPI038848.
DR VEuPathDB; VectorBase:GPPI038848; -.
DR Proteomes; UP000092460; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd04146; RERG_RasL11_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001806; Small_GTPase.
DR PANTHER; PTHR45704:SF1; RAS-LIKE FAMILY 11 MEMBER A; 1.
DR PANTHER; PTHR45704; RAS-LIKE FAMILY MEMBER 11; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
PE 3: Inferred from homology;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..347
FT /note="small monomeric GTPase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008405178"
FT REGION 277..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 347 AA; 39360 MW; 5D2A9D6374D03D88 CRC64;
MNSVQAVIIL HFSSFLRLFC QMNTTSPKSS LAKLGIHPKH KSLKVMVLGQ SGVGKTAMVV
RFITKRFIGE YDPNLEKIYT HNTILDNDYA QFDILDAAGQ PNEIDAINLE SNIRWADAFV
LMYSVTDKCS FDECNRLKFL INYNKRRRKL GSNHKDCMSD VPVILVGNKT DQTGDRMVGL
EEGQRRFKEL SCACFHEISV RESVDQVQAV FRDVFRFWRV FSKFPKLKRS TSDVQNTNDL
VMSPDSGCSF HDSASLAHET RRSFLIIGSA CLEETDHSES TDELGSGSLN SSQSELETPF
RSRACTDGTL LSRPRRWRYP PPGCLMPHTN RVERRMSIST RGSNASY
//
