ID A0A1B0BV64_9MUSC Unreviewed; 1144 AA.
AC A0A1B0BV64;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Transient receptor ion channel domain-containing protein {ECO:0000259|SMART:SM01420};
OS Glossina palpalis gambiensis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=67801 {ECO:0000313|EnsemblMetazoa:GPPI041466-PA, ECO:0000313|Proteomes:UP000092460};
RN [1] {ECO:0000313|Proteomes:UP000092460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000092460};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GPPI041466-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPPI041466-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JXJN01021148; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0BV64; -.
DR STRING; 67801.A0A1B0BV64; -.
DR EnsemblMetazoa; GPPI041466-RA; GPPI041466-PA; GPPI041466.
DR VEuPathDB; VectorBase:GPPI041466; -.
DR Proteomes; UP000092460; Unassembled WGS sequence.
DR GO; GO:0034703; C:cation channel complex; IEA:UniProt.
DR GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR013555; TRP_dom.
DR InterPro; IPR002153; TRPC_channel.
DR NCBIfam; TIGR00870; trp; 1.
DR PANTHER; PTHR10117; TRANSIENT RECEPTOR POTENTIAL CHANNEL; 1.
DR PANTHER; PTHR10117:SF54; TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF08344; TRP_2; 1.
DR PRINTS; PR01097; TRNSRECEPTRP.
DR SMART; SM00248; ANK; 2.
DR SMART; SM01420; TRP_2; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 323..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 534..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 628..653
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 131..163
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 166..228
FT /note="Transient receptor ion channel"
FT /evidence="ECO:0000259|SMART:SM01420"
FT REGION 1091..1144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1101..1144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1144 AA; 129421 MW; 6B31C459D3EE2541 CRC64;
MMEEENIIRP HQEIRQLTLE EKKFLLAVER GDMAGTRRML QKAQDTDYIN INCVDPLGRT
ALLMAIDNEN LEMVELLINY NVDTKDALLH SISEEFVEAV EVLLDHENIT FQNEGNHSWE
SSSEDTSTFT PDVTPLILAA HRDNYEIIKI LLDRGAVLPM PHDVRCGCDE CVQSRQEDSL
RHSRSRINAY RALASPSLIA LSSKDPILTA FELSWELRRL SFLEHEFKNE YQELRKQCQD
FATALLDHTR TSHELEILLN HDPTGPVYEH GERMHLNRLK LAIKLRQKKF VAHPNVQQLL
ASIWYEGLPG FRRKNMALQA VDIIRIGIMF PIFSLAYILA PYSSIGQTMR KPFIKFICHS
ASYFTFLFLL MLASQRIETF IGGWFWSETK AVIHHQVEEL PTKRGAKPTF IEWLILAWVS
GLIWSEVKQL WDVGLQEYLN DMWNVIDFVT NSLYVATVAL RVVSFFQVQK EMITNPNATD
LPRERWDTWD PMLISEGLFS AANIFSSLKL VYIFSVNPHL GPLQVSLSRM VMDIMKFFFL
YVLVLFAFGS GLNQLLWYYA DLEKKRCPEV SPTNVLINLN GTTDPNACIV WRRFSNLFET
TQTLFWAVFG LIDLDSFELD GIKIFTRFWG MLMFGTYSVI NIVVLLNLLI AMMNHSYQLI
SERADIEWKF ARSKLWISYF EEGGTCPPPF NIIPTPKSIW YAFKWARRVF CSGSSAARRE
HLKTIRRKAQ QANDRDFKYQ QIMRNLVRRY VTVEQRKAES QGVTEDDVNE IKQDISAFRC
ELVEILKNSG MDTNVSAGQA GGGGGGKKNR QKERRLMKGF NIAPPGSTGS LAPVAEFSTS
LDNFEQQHEI LTSTLSTLFT PTFMHKKPSY CASDSCNSME SPSALPPATL MPPMNTVQTI
NKYNKSALKP YNKRIAGHKK KWGTLIEAAK VGNVTKMLGR SKSEDSVCNS SQNSSPVHGQ
VRVTYSQNCG QNYYNSGSGG ETNLSNSSYN KDYLSTKQTG SHLSHALHGI GGGGGTHFFH
ATTGLTAIAA LKKKRKKFSS SKNICPVNES ISTANGVDLL SDKALKRVSS YPASTNDANA
QNKDPLIGAK PRRHEQTQSQ HDSVETSAEF TLSSEIQHLD PSNTSVNSRE PLISNSCASN
GVMS
//
