ID A0A1B0C0Z8_9MUSC Unreviewed; 1285 AA.
AC A0A1B0C0Z8;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=Zinc finger protein ush {ECO:0008006|Google:ProtNLM};
OS Glossina palpalis gambiensis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=67801 {ECO:0000313|EnsemblMetazoa:GPPI046294-PA, ECO:0000313|Proteomes:UP000092460};
RN [1] {ECO:0000313|Proteomes:UP000092460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IAEA {ECO:0000313|Proteomes:UP000092460};
RA Aksoy S., Warren W., Wilson R.K.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:GPPI046294-PA}
RP IDENTIFICATION.
RC STRAIN=IAEA {ECO:0000313|EnsemblMetazoa:GPPI046294-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JXJN01023842; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 67801.A0A1B0C0Z8; -.
DR EnsemblMetazoa; GPPI046294-RA; GPPI046294-PA; GPPI046294.
DR VEuPathDB; VectorBase:GPPI046294; -.
DR Proteomes; UP000092460; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061629; F:RNA polymerase II-specific DNA-binding transcription factor binding; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 3.
DR InterPro; IPR039746; FOG.
DR InterPro; IPR034731; ZF_CCHC_FOG.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR12958; FRIEND OF GATA2-RELATED; 1.
DR PANTHER; PTHR12958:SF3; ZINC FINGER PROTEIN USH; 1.
DR Pfam; PF13909; zf-H2C2_5; 1.
DR Pfam; PF12874; zf-met; 2.
DR SMART; SM00355; ZnF_C2H2; 8.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 6.
DR PROSITE; PS51810; ZF_CCHC_FOG; 5.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 207..240
FT /note="CCHC FOG-type"
FT /evidence="ECO:0000259|PROSITE:PS51810"
FT DOMAIN 213..243
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 287..314
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 341..374
FT /note="CCHC FOG-type"
FT /evidence="ECO:0000259|PROSITE:PS51810"
FT DOMAIN 768..801
FT /note="CCHC FOG-type"
FT /evidence="ECO:0000259|PROSITE:PS51810"
FT DOMAIN 828..861
FT /note="CCHC FOG-type"
FT /evidence="ECO:0000259|PROSITE:PS51810"
FT DOMAIN 1210..1243
FT /note="CCHC FOG-type"
FT /evidence="ECO:0000259|PROSITE:PS51810"
FT REGION 1..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 310..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 383..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 625..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1138..1211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1244..1271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..70
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..279
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..537
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1138..1165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1248..1271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1285 AA; 137987 MW; 28EDB87B680D1EA0 CRC64;
MDTEHNQQDR QTPKDLLSET VGVEMTNENL KRHKLEPMET TTIHEKGDDK DKESFKTQHM
EDEDLTRSSN GSIDNKDTYG DAKCDINRIS NIREHSSPNV RTSTPQQTPP LSPAKSMDDS
ISESKSSPAS NSNLPKLRLN TLLASDPALM PDAKDLKLIQ EEAKTQQRKN QLAQGSPEEL
DSLMITPANN LMETSVLKPV TPNVEVPTRM KVFMCLPCGI GFSSPSTLEA HQAYYCSHRH
KDMDDDTSLS AEKNSTSPSS GQATVSSTPS NQSSEPLAKA LKTGKQYACT QCSYSADKKV
SLNRHMRMHQ TSPASTTNAS NNNNNSIGGG SAAGTQMEEN SSQQIDRYCS DCDIRFNNVK
TYRAHKQHYC SSRRNEGQLT PKLEVSTPTS SSLAKPSISV TGTISPQNRT KTPTPAMVAA
AAAAAAAALQ QSPSTPFLAL PTNPILIIPY SLIRSASLIA GPLTSPSPGV INPDTTCFTL
DNGNLKPFAT ALNINAINAA NANSIANSTA PPAPSAADSA RHQQQSTNNN NESLLTEKNI
KHNVEVNDEI VRRKEGPLRE TAPLDLSLRR SPIAALLQRT RLHPASSAFL ETEQQIEMES
LLETGKENVA LDEGGNITPE QIVCAPSLPN SPSMSPSPKR RTISPRSSGA GSTSSISPPV
STTSLNSINN STSLLDNLQL RSMLPADLLN PLLAKQNLEL ALKLSAAAAA AVSSSSAAMP
TPGSATAELA AAAVAAAAGR NSLLGLPVLP SVATSSGGPP AGNQPQIYVK QGVSKCKECN
IVFCKYENYL AHKQHYCSAR NQEASDSDSK VSSTPPIGAA AASTEATPVA YQQLICAACG
IKYTSLDNLR AHQNYYCPKG GGAAAAAAVA AAAVAATDSN QLSQAKEKCS KCKNIHEIGL
PCPPPPALQQ QQQQPTLIPN SSSACGNNQN VYKCPLCDAV SLTATESRKH METHGTVKAF
RCTICRYKGN TLRGMRTHIR MHFDKKTTDL NEEHYMSCIL EDESIEIPSA ASLNTEQLAQ
QQKHLQQAAA AAAVAAGFQQ QQQQQQQQQQ QGQQVFNCDI CNYTSTYKGN VLRHMKLLHP
HIVTNSPSMS PETGDLEIAD VGSVASNLNG DNNVNSFAIK SEPIEHTTTA ISNTPGIMLN
PHDNNNSPLL NTSTTSTTAA TNANPNELMM PHIKSEPMEI SIDPPSSLTL PPNLRSPALG
PPPPLNTTPE ENINQKYCQT CDISFNYMKT YLAHKQFYCK SKLRRPETND SPSPNSANLI
TSMPSPNSLP LLQKNKENMQ QEAAI
//
