ID A0A1B0C9L7_LUTLO Unreviewed; 1342 AA.
AC A0A1B0C9L7;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:LLOJ000639-PA};
OS Lutzomyia longipalpis (Sand fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC Lutzomyia; Lutzomyia.
OX NCBI_TaxID=7200 {ECO:0000313|EnsemblMetazoa:LLOJ000639-PA, ECO:0000313|Proteomes:UP000092461};
RN [1] {ECO:0000313|Proteomes:UP000092461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Jacobina {ECO:0000313|Proteomes:UP000092461};
RA Richards S., Qu C., Dillon R., Worley K., Scherer S., Batterton M.,
RA Taylor A., Hawes A., Hernandez B., Kovar C., Mandapat C., Pham C., Qu C.,
RA Jing C., Bess C., Bandaranaike D., Ngo D., Ongeri F., Arias F., Lara F.,
RA Weissenberger G., Kamau G., Han H., Shen H., Dinh H., Khalil I., Jones J.,
RA Shafer J., Jayaseelan J., Quiroz J., Blankenburg K., Nguyen L., Jackson L.,
RA Francisco L., Tang L.-Y., Pu L.-L., Perales L., Lorensuhewa L.,
RA Munidasa M., Coyle M., Taylor M., Puazo M., Firestine M., Scheel M.,
RA Javaid M., Wang M., Li M., Tabassum N., Saada N., Osuji N., Aqrawi P.,
RA Fu Q., Thornton R., Raj R., Goodspeed R., Mata R., Najjar R., Gubbala S.,
RA Lee S., Denson S., Patil S., Macmil S., Qi S., Matskevitch T.,
RA Palculict T., Mathew T., Vee V., Velamala V., Korchina V., Cai W., Liu W.,
RA Dai W., Zou X., Zhu Y., Zhang Y., Wu Y.-Q., Xin Y., Nazarath L., Kovar C.,
RA Han Y., Muzny D., Gibbs R.;
RT "Whole Genome Assembly of Lutzomyia longipalpis.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:LLOJ000639-PA}
RP IDENTIFICATION.
RC STRAIN=Jacobina {ECO:0000313|EnsemblMetazoa:LLOJ000639-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AJWK01002463; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJWK01002464; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EnsemblMetazoa; LLOJ000639-RA; LLOJ000639-PA; LLOJ000639.
DR VEuPathDB; VectorBase:LLOJ000639; -.
DR OrthoDB; 3384185at2759; -.
DR Proteomes; UP000092461; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03250; ABCC_MRP_domain1; 1.
DR CDD; cd03244; ABCC_MRP_domain2; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24223; ATP-BINDING CASSETTE SUB-FAMILY C; 1.
DR PANTHER; PTHR24223:SF448; FI20146P1-RELATED; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 17..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 712..734
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 802..827
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 872..893
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 899..919
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 985..1007
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1013..1033
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 64..325
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 419..642
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 802..1041
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1079..1314
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 642..691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 642..663
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..680
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1342 AA; 150601 MW; AC0B5FF7D3A186DA CRC64;
MEALSESKKP ANPREKANFF SYLVFWWVLP IFFKGRKQEL GEDDIYEALK CHKSDYLGNR
MCKAVSQPLF LGGLIAYYSS GDGVIRDAYL YAGAVVLCSA LTVLFMHSFM LSNLHEGMKL
RVSMCSMIYR KALRLSKNAL GDTTVGQVVN LLSNDVGRLD LSIIFLHYLW VGPLETLVVT
YLMYREVGVS AVFGVIFLLL FIPLQAYLGK KTSVLRLKTA LRTDERVRLM NEIIQGIQVI
KMYAWEKPFG KLVEKARIKE LKVIRYVSYI RGILLSFIIF STRVSVFISL VAFALLGNVV
TAEKAFVITS YYNILRQTMT IFFPQGIAQL AETLVSIKRI QKYMLYNETD IGREEFTVDA
SNDSTFNEYE KVPNSTQSTI TKGSDDIKYI DSHESLTEAT TYTDEKPAQM NGNLNPVGIT
IKSLMAKWDP LVMDNTLHDV SLQIKPATLM AIIGPVGAGK SSLIQAILGE LPATSGQIDI
NGVLSYASQE PWLFSGSIRQ NILFGQPMEK KRYREVVKRC ALEKDFSLFA NGDKTIVGER
GQSLSGGQKA RISLARAVYR QAAIYLLDDP LSAVDTHVGR HLFDQCMRNF LRGKIVILVT
HQLQYLQHAD QIVILDKGRI QDVGTYESLR ESGLDFAKML RESKEEGKSD ENEDSRSRSG
SKTYQRRISE TSLESLDQTH DTPMQTEEGR KEGSVGFGMY KKYFQASGGF CAFYWMMLFC
VTAQLCASAG DYFLTYWVNK EEQRNVEVLL AMTRDNANDS FVDANHLPGD ASVNATESNG
TDFFAKILKY VGAEDYNNYV DIYIFTALTI ATVVITLSRS FIFFNLAVRA AKVLHNAMYT
GVTKASMYFF NTNPSGRILN RFSKDMGQVD EFLPTVMIDV IQIFLSLAGI IVVVAVVNYW
LLIPTVIIGI IFYFLRDFYL ITSRSVKRIE ATTRSPIYSH LGASLTGLST IRAFKTQRVL
VKEFDSLQDL NSSAFYVFIS TSRAFGFWLD VFCVIYIAIV TLSFFLMGDA FGGNVGLAIT
QAIGMTGMVQ WGMRQSAELE NTMTAVERVV EYQTVDPEGQ LEAIGDKKPP SSWPEEGKVT
FDRLSLRYFP TKDADRVLKE LEFEIRPREK IGIVGRTGAG KSSLINALFR LSYNEGSIII
DARDTGSMGL HDLRKKISII PQEPVLFSGS MRYNLDPFDE YPDEKLWKAL DDVKLKAVIT
DLPSGLQSKI SEGGSNFSVG QRQLVCLARA LLRENKILVM DEATANVDPQ TDNLIQATIR
QMFADCTVLT IAHRLNTVMD SDRVLVMDAG RAVEFAPPYE LLTGISGSGI FEGMLRETGK
GTYDQLLEVA RKNYERSHQT NA
//
