ID A0A1B0CDR8_LUTLO Unreviewed; 1007 AA.
AC A0A1B0CDR8;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=G-alpha gtpase interaction protein {ECO:0008006|Google:ProtNLM};
OS Lutzomyia longipalpis (Sand fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC Lutzomyia; Lutzomyia.
OX NCBI_TaxID=7200 {ECO:0000313|EnsemblMetazoa:LLOJ002488-PA, ECO:0000313|Proteomes:UP000092461};
RN [1] {ECO:0000313|Proteomes:UP000092461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Jacobina {ECO:0000313|Proteomes:UP000092461};
RA Richards S., Qu C., Dillon R., Worley K., Scherer S., Batterton M.,
RA Taylor A., Hawes A., Hernandez B., Kovar C., Mandapat C., Pham C., Qu C.,
RA Jing C., Bess C., Bandaranaike D., Ngo D., Ongeri F., Arias F., Lara F.,
RA Weissenberger G., Kamau G., Han H., Shen H., Dinh H., Khalil I., Jones J.,
RA Shafer J., Jayaseelan J., Quiroz J., Blankenburg K., Nguyen L., Jackson L.,
RA Francisco L., Tang L.-Y., Pu L.-L., Perales L., Lorensuhewa L.,
RA Munidasa M., Coyle M., Taylor M., Puazo M., Firestine M., Scheel M.,
RA Javaid M., Wang M., Li M., Tabassum N., Saada N., Osuji N., Aqrawi P.,
RA Fu Q., Thornton R., Raj R., Goodspeed R., Mata R., Najjar R., Gubbala S.,
RA Lee S., Denson S., Patil S., Macmil S., Qi S., Matskevitch T.,
RA Palculict T., Mathew T., Vee V., Velamala V., Korchina V., Cai W., Liu W.,
RA Dai W., Zou X., Zhu Y., Zhang Y., Wu Y.-Q., Xin Y., Nazarath L., Kovar C.,
RA Han Y., Muzny D., Gibbs R.;
RT "Whole Genome Assembly of Lutzomyia longipalpis.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:LLOJ002488-PA}
RP IDENTIFICATION.
RC STRAIN=Jacobina {ECO:0000313|EnsemblMetazoa:LLOJ002488-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GPSM family.
CC {ECO:0000256|ARBA:ARBA00006600}.
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DR EMBL; AJWK01008177; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJWK01008178; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJWK01008179; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EnsemblMetazoa; LLOJ002488-RA; LLOJ002488-PA; LLOJ002488.
DR VEuPathDB; VectorBase:LLOJ002488; -.
DR OrthoDB; 4190321at2759; -.
DR Proteomes; UP000092461; Unassembled WGS sequence.
DR GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 5.
DR InterPro; IPR003109; GoLoco_motif.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45954; LD33695P; 1.
DR PANTHER; PTHR45954:SF1; LD33695P; 1.
DR Pfam; PF02188; GoLoco; 4.
DR Pfam; PF13424; TPR_12; 3.
DR Pfam; PF13176; TPR_7; 1.
DR SMART; SM00390; GoLoco; 4.
DR SMART; SM00028; TPR; 8.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50877; GOLOCO; 4.
DR PROSITE; PS50005; TPR; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 61..94
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 236..269
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 676..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 753..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 919..951
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 977..1007
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..700
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 756..778
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 919..942
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1007 AA; 110633 MW; 60C94EC46330FCE6 CRC64;
MSSLSASAEN LTDTQGNDGS SMCLELALEG ERLCKSGDCR AGVAFFQAAI QAGTDDLRIL
SAIYSQLGNA YFYLGDYSKA MDFHKLDLTL ARSMNDKLGE AKSSGNLGNT LKVMGKFDEA
AICCERHLTL ARQLGDRLSE SRALYNLGNV YHSKGKHMGQ RDPGDFSDDV KEALMKAVGY
YHAENLTDTQ GNDGSSMCLE LALEGERLCK SGDCRAGVAF FQAAIQAGTD DLRILSAIYS
QLGNAYFYLG DYSKAMDFHK LDLTLARSMN DKLGEAKSSG NLGNTLKVMG KFDEAAICCE
RHLTLARQLG DRLSESRALY NLGNVYHSKG KHMGQRDPGD FSDDVKEALM KAVGYYHLKT
ELSGYLATMT NFRNTLEEIS VEELKKNLNL SPEDSNALMK EVEGKPIGEI LKNLQRDAEN
FKPNFRDSSM ENFVSSLDDV MQSMARLREC SETIVKIDKR IEETLQEAQN NISLVSFLEQ
NLTLMRQIGD RGAQGRACGN LGNTYYLLGD FQAAIVHHQE RLSIAREFGD KAAERRANSN
LGNSHIFLGQ FELAAENYKR TLSLAIELGE RAVEAQACYS LGNTYTLLKD FALAIEYHQR
HLAIAQELGD KVGEARACWS LGNAYSAIGN YEKALHYAQS HYSLATELGD PVGESTARMN
ITDLRKVLGL PEITPTDFDA ISSDSQRSKS SPDEQETTQT VXXXXXXXXX XXXXXXXXDL
ILKFDLGDPV GESTARMNIT DLRKVLGLPE ITPTDFDAIS SDSQRSKSSP DEQETTQTVR
QYRLTPDGKK VEHHAKGSDG GAIMQEDDFF ELLTNSQSKR MDDQRCSLKV GGAVVGEGAV
RKPLVAQNRN APPAGAKENR NALLEMIADL QSERMDEQRA TLPGLVNRGG VVLKGQTNPT
GPAPDDAFLD MLMRCQGSRL EEQRSELPRP GDVLDDAEGG STRRGRSNIG ATVPDEDFFS
LISRVQGGRM EDQRAAVPLG VSRRLAMPNN VHVPPPNTTT KESGKKN
//
