ID A0A1B0CEQ0_LUTLO Unreviewed; 526 AA.
AC A0A1B0CEQ0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 13-SEP-2023, entry version 24.
DE SubName: Full=Putative histone tail methylase {ECO:0000313|EMBL:MBC1175681.1};
OS Lutzomyia longipalpis (Sand fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC Lutzomyia; Lutzomyia.
OX NCBI_TaxID=7200 {ECO:0000313|EnsemblMetazoa:LLOJ002820-PA, ECO:0000313|Proteomes:UP000092461};
RN [1] {ECO:0000313|Proteomes:UP000092461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Jacobina {ECO:0000313|Proteomes:UP000092461};
RA Richards S., Qu C., Dillon R., Worley K., Scherer S., Batterton M.,
RA Taylor A., Hawes A., Hernandez B., Kovar C., Mandapat C., Pham C., Qu C.,
RA Jing C., Bess C., Bandaranaike D., Ngo D., Ongeri F., Arias F., Lara F.,
RA Weissenberger G., Kamau G., Han H., Shen H., Dinh H., Khalil I., Jones J.,
RA Shafer J., Jayaseelan J., Quiroz J., Blankenburg K., Nguyen L., Jackson L.,
RA Francisco L., Tang L.-Y., Pu L.-L., Perales L., Lorensuhewa L.,
RA Munidasa M., Coyle M., Taylor M., Puazo M., Firestine M., Scheel M.,
RA Javaid M., Wang M., Li M., Tabassum N., Saada N., Osuji N., Aqrawi P.,
RA Fu Q., Thornton R., Raj R., Goodspeed R., Mata R., Najjar R., Gubbala S.,
RA Lee S., Denson S., Patil S., Macmil S., Qi S., Matskevitch T.,
RA Palculict T., Mathew T., Vee V., Velamala V., Korchina V., Cai W., Liu W.,
RA Dai W., Zou X., Zhu Y., Zhang Y., Wu Y.-Q., Xin Y., Nazarath L., Kovar C.,
RA Han Y., Muzny D., Gibbs R.;
RT "Whole Genome Assembly of Lutzomyia longipalpis.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MBC1175681.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Jacobina {ECO:0000313|EMBL:MBC1175681.1};
RC TISSUE=Midgut {ECO:0000313|EMBL:MBC1175681.1};
RA Coutinho-Abreu I.V., Serafim T.D., Meneses C., Kamhawi S., Oliveira F.,
RA Valenzuela J.G.;
RT "Leishmania infection induces a limited differential gene expression in the
RT sand fly midgut.";
RL BMC 21:608-608(2020).
RN [3] {ECO:0000313|EnsemblMetazoa:LLOJ002820-PA}
RP IDENTIFICATION.
RC STRAIN=Jacobina {ECO:0000313|EnsemblMetazoa:LLOJ002820-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AJWK01009066; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GITU01006978; MBC1175681.1; -; Transcribed_RNA.
DR AlphaFoldDB; A0A1B0CEQ0; -.
DR EnsemblMetazoa; LLOJ002820-RA; LLOJ002820-PA; LLOJ002820.
DR VEuPathDB; VectorBase:LLOJ002820; -.
DR OrthoDB; 130569at2759; -.
DR Proteomes; UP000092461; Unassembled WGS sequence.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd20071; SET_SMYD; 1.
DR Gene3D; 1.10.220.160; -; 1.
DR Gene3D; 6.10.140.2220; -; 2.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR46455:SF1; SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 2; 1.
DR PANTHER; PTHR46455; SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:MBC1175681.1};
KW Transferase {ECO:0000313|EMBL:MBC1175681.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 8..45
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT DOMAIN 46..289
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
SQ SEQUENCE 526 AA; 59647 MW; D2A3C27CA19F585F CRC64;
MAPSISSCAV CGVEANLKCG GCKNVVYCGK DHQKVHWRKG HKAMCKCVEL KVDEVMGRYL
SATRDIKQGE VIFREKPLAI GPKVSCMPMC LGCNVFLTLK PKEKNYYKCS QCNWPLCGPS
CEKSPLHTEE CSLMASRKFK AQINATPAEE GKKEAAYCAI VPLRCCLLKE SDPEGFQRLC
ELQSHLEKRI ETPLYRVLKA NLITFIKTIL RLDFDEFTIM RITAILDTNC FEIRHQHKNI
KVRALYPQAS MIAHSCVPNT THVFSEDFEF VLIATVDIAK GSPIFVTYGQ TLQGTLQRRE
HLRQVKFFEC FCERCADPTE LSTFAGSFNC TRCNNGKMIP TNPFEDTAPW RCSACESEIS
AKQVINGNRA IMTEISELDQ HSPKEFEAFL LKYRDILHGT NTHMLQVKYA LSQLYGNIPG
FQLQQLSEAA IIRKIDICRE LLEVGKLLEP GLSFFRGYLL MDLQSVLAIQ AKRDFDNKTA
NREETLRLLT EAMDLLQEAV KILSPDPALK EFIDTKVQEM TTLMQL
//
