ID A0A1B0CK24_LUTLO Unreviewed; 1273 AA.
AC A0A1B0CK24;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
OS Lutzomyia longipalpis (Sand fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC Lutzomyia; Lutzomyia.
OX NCBI_TaxID=7200 {ECO:0000313|EnsemblMetazoa:LLOJ004961-PA, ECO:0000313|Proteomes:UP000092461};
RN [1] {ECO:0000313|Proteomes:UP000092461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Jacobina {ECO:0000313|Proteomes:UP000092461};
RA Richards S., Qu C., Dillon R., Worley K., Scherer S., Batterton M.,
RA Taylor A., Hawes A., Hernandez B., Kovar C., Mandapat C., Pham C., Qu C.,
RA Jing C., Bess C., Bandaranaike D., Ngo D., Ongeri F., Arias F., Lara F.,
RA Weissenberger G., Kamau G., Han H., Shen H., Dinh H., Khalil I., Jones J.,
RA Shafer J., Jayaseelan J., Quiroz J., Blankenburg K., Nguyen L., Jackson L.,
RA Francisco L., Tang L.-Y., Pu L.-L., Perales L., Lorensuhewa L.,
RA Munidasa M., Coyle M., Taylor M., Puazo M., Firestine M., Scheel M.,
RA Javaid M., Wang M., Li M., Tabassum N., Saada N., Osuji N., Aqrawi P.,
RA Fu Q., Thornton R., Raj R., Goodspeed R., Mata R., Najjar R., Gubbala S.,
RA Lee S., Denson S., Patil S., Macmil S., Qi S., Matskevitch T.,
RA Palculict T., Mathew T., Vee V., Velamala V., Korchina V., Cai W., Liu W.,
RA Dai W., Zou X., Zhu Y., Zhang Y., Wu Y.-Q., Xin Y., Nazarath L., Kovar C.,
RA Han Y., Muzny D., Gibbs R.;
RT "Whole Genome Assembly of Lutzomyia longipalpis.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:LLOJ004961-PA}
RP IDENTIFICATION.
RC STRAIN=Jacobina {ECO:0000313|EnsemblMetazoa:LLOJ004961-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AJWK01015649; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJWK01015650; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0CK24; -.
DR EnsemblMetazoa; LLOJ004961-RA; LLOJ004961-PA; LLOJ004961.
DR VEuPathDB; VectorBase:LLOJ004961; -.
DR OrthoDB; 2910129at2759; -.
DR Proteomes; UP000092461; Unassembled WGS sequence.
DR GO; GO:0034703; C:cation channel complex; IEA:UniProt.
DR GO; GO:0005261; F:monoatomic cation channel activity; IEA:UniProt.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 5.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR PANTHER; PTHR47143; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS; 1.
DR PANTHER; PTHR47143:SF3; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS; 1.
DR Pfam; PF12796; Ank_2; 5.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 14.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR PROSITE; PS50297; ANK_REP_REGION; 9.
DR PROSITE; PS50088; ANK_REPEAT; 11.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 899..919
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 939..957
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 964..984
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1004..1025
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1075..1101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 141..173
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 174..206
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 242..263
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 317..349
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 388..420
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 421..453
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 495..527
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 528..560
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 564..596
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 596..616
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 630..652
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 863..1111
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
SQ SEQUENCE 1273 AA; 143174 MW; 99C419A573DAF165 CRC64;
MIRIFTVMPS PFYMLHNTRA ISPAATDANS NGQNQDDVPT VVVSTDVPDI QKNVSLKTWI
LTKIIGQSLE NMRKDVDKTA PGASENETGQ ELQAILAPVQ EVCLLRDSPF RILRAAEAGN
LEDFARLYNT DNSRLNVKDG KGRTAAHQAA ARNRVNILQF IRDEQGDLNA QDSLGNTPLH
IAVENDSLDA LDFLLSIPVN TTVLNDKKQA PVHLATELNK VAALQVMGKH RNAIDIQQGG
EHGRTALHLA AIYDHEECAR ILITEFKACP RRPCNNGYYP IHEAAKNASS KTMEVFLQWG
ESRGSSREEM ISFYDSEGNV PLHSAVHGGD IKAVELCLKS GAKISTQQHD LSTPVHLACA
QGALDIVKLM FTLQPKEKKV SLSCTDVQRM TPLHCASMFD HPDIVEYLVE NGADINALDK
EHRSPLLLSA SRAGWRTVHT LIRLGANISL KDANNRNVLH LVIMNGGRLE EFAMEVSKAQ
SQSHLLQLLN EKDNTGCSPL HYASREGHIK SLQNLISLGA CINLKNNNNE SPLHFAARYG
RFNTVRQLLD SEKGTFIINE SDGEGLTPLH IASKQGHTRV VQLLLNRGAL LHRDHNGRNP
LHLAAMSGYT QTIELLHSVH SHLLDQVDKD GNTALHLATM ENKPNAITLL LSMDCKLLYN
YMDMSAIDYA IYYKYPEAAL SMVTHEERAS EIMALKSDKH PCVTLALIAS MPRVFEAVQD
KCITKANCKK DSKSFYIKYC FSTLQCPMMY AQMDEKTGNA VQISKPIPLP ALNIKYSFSA
YQKSQAKIDE MRIILNDPKW RPPPLDVVNA MVSHGRVELL AHPLSQKYLQ MKWNSYGKYF
HLANLLFYCV FLFFVTMFSS QLMHSHVVTA IPDNITNITD NATTIPHGAF HHHKRTLEVT
TIMMVSGMAI VAYIAINSLR EIVQVYQQKW QYLLEPNNLV SWTLHVSALT MISALFCGGH
ISDAHYSAAS VTVFLSWFNL LLFLQRFDQV GIYVVMFLEI LQTLIKVLMV FSILIIAFGL
AFYILLSNSL YLQTTYSFSS IPMSLMRTFS MMLGEMDFVG TYVQPLHRNE LPYPIPAFVI
LCLFMILMPI LLMNLLIGLA VGDIESVRRN AQLKRLAMQV VLHTELEQKL PQMWLEKVDK
MELIEYPNDT KCKLGFLDSI LRKWFCNPFN EDAGLDMVLD STNAEDYLAN EIDKQKRKLR
EITSTLEQQH QLLRLIVQKM EIKTEADDVD EGVPPNDLRP LSAAPFSSVN NSRWTSPRIR
KKLRSAISFN KNL
//
