ID A0A1B0CKY4_LUTLO Unreviewed; 935 AA.
AC A0A1B0CKY4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Transcriptional-regulating factor 1 {ECO:0008006|Google:ProtNLM};
OS Lutzomyia longipalpis (Sand fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC Lutzomyia; Lutzomyia.
OX NCBI_TaxID=7200 {ECO:0000313|EnsemblMetazoa:LLOJ005271-PA, ECO:0000313|Proteomes:UP000092461};
RN [1] {ECO:0000313|Proteomes:UP000092461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Jacobina {ECO:0000313|Proteomes:UP000092461};
RA Richards S., Qu C., Dillon R., Worley K., Scherer S., Batterton M.,
RA Taylor A., Hawes A., Hernandez B., Kovar C., Mandapat C., Pham C., Qu C.,
RA Jing C., Bess C., Bandaranaike D., Ngo D., Ongeri F., Arias F., Lara F.,
RA Weissenberger G., Kamau G., Han H., Shen H., Dinh H., Khalil I., Jones J.,
RA Shafer J., Jayaseelan J., Quiroz J., Blankenburg K., Nguyen L., Jackson L.,
RA Francisco L., Tang L.-Y., Pu L.-L., Perales L., Lorensuhewa L.,
RA Munidasa M., Coyle M., Taylor M., Puazo M., Firestine M., Scheel M.,
RA Javaid M., Wang M., Li M., Tabassum N., Saada N., Osuji N., Aqrawi P.,
RA Fu Q., Thornton R., Raj R., Goodspeed R., Mata R., Najjar R., Gubbala S.,
RA Lee S., Denson S., Patil S., Macmil S., Qi S., Matskevitch T.,
RA Palculict T., Mathew T., Vee V., Velamala V., Korchina V., Cai W., Liu W.,
RA Dai W., Zou X., Zhu Y., Zhang Y., Wu Y.-Q., Xin Y., Nazarath L., Kovar C.,
RA Han Y., Muzny D., Gibbs R.;
RT "Whole Genome Assembly of Lutzomyia longipalpis.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:LLOJ005271-PA}
RP IDENTIFICATION.
RC STRAIN=Jacobina {ECO:0000313|EnsemblMetazoa:LLOJ005271-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AJWK01016785; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJWK01016786; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJWK01016787; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0CKY4; -.
DR EnsemblMetazoa; LLOJ005271-RA; LLOJ005271-PA; LLOJ005271.
DR VEuPathDB; VectorBase:LLOJ005271; -.
DR OrthoDB; 2906194at2759; -.
DR Proteomes; UP000092461; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 4.10.1240.50; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR000949; ELM2_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR16089; REST COREPRESSOR COREST PROTEIN-RELATED; 1.
DR PANTHER; PTHR16089:SF40; SUPPRESSOR OF ACTIVATED EGL-4 PROTEIN 1; 1.
DR Pfam; PF01448; ELM2; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR Pfam; PF13912; zf-C2H2_6; 1.
DR SMART; SM01189; ELM2; 1.
DR SMART; SM00717; SANT; 1.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51156; ELM2; 1.
DR PROSITE; PS51293; SANT; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 658..748
FT /note="ELM2"
FT /evidence="ECO:0000259|PROSITE:PS51156"
FT DOMAIN 751..802
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT DOMAIN 851..880
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 903..930
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 146..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 885..904
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 916..935
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..541
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 885..900
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 935 AA; 102478 MW; EC24BE370DD2137A CRC64;
MRLHGGYFKK DAETKKCDKK ETPGPPLQTA SVGVRALIEE KIISKRSKDL KGAFVVPAPP
LAARRLSDTE SFLSSKLTPS TSAGVTLPSL CHTTTTTIAT ALQIATSVAP TVAGKTTKTD
VVLSSSQPDS KDATLIELLK RGTKVAVKRT SSDPGTAAQP PPPPLVAETS TGSSVTKSTP
GTPTTTPPLA LSIGTNESTP LALTISQDAP GTSDVFTLAY STDSNSGFFH DNEVYGVNDT
AMLLQAVDSI QLLHEGTTNS EQIDDMNALG DYATLTPNFA SSRQLQAVLN SPLPESLAEF
STLHSKDYIL YGNSPSAVTQ SSASPLPSPL AYPTPPASHE AVAQASPFLD DSHHFADVGP
FFGDEKKPTA FLEDVSKELT DNERIMQLKN ELFSDSKSML DEKPDIFKED PDRDRLRDLA
FLDEPDSFLE DAQNPSSPLS AAFFSATMSS AEEVKEALQE VLPNENLTEE TATETDDIDL
YYLPMCNLQS QMMPNSDDPL LSSSPKEFVS RPNRFEFGVF CPPSAKRTKG NNTSDDNVQP
TATPLTVQTE QPLPPKDSEV FLSPSSISSA STPSPKMLPL ASLVTRKRHH TEHYARVYER
FRSRLRNINT SHFTPSPILN PSRNASGIYF CLIKDGLQEE DDCLLSSSED LTNLLDSPRI
NIGVNHQARI PECVERDTVE DDEQENAEDI LQWDPTFVTD ERQLRRYVEL SKSSAVPMGT
HSEEMALKTL MESHGEIHKA ILELLQAPAT ALHKRWTPQE IKLFLKGLET FRKDFYRISK
EIPHKSTGDC IQLYYFWKKL CVDYKLTHLQ QNNQRRISHE LNNNAPLVFG TDSHHTPSTL
SHTSHTDIRP HICEMPDCSA SFSSKAALHG HTKLHCMGRS MNVSSSASTS SSSSSGSTVK
DDFPCKVCGK VFNKVKSRSA HMKSHRPQDS DSSTA
//
