ID A0A1B0CTI0_LUTLO Unreviewed; 730 AA.
AC A0A1B0CTI0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Putative vigilin {ECO:0000313|EMBL:MBC1180799.1};
OS Lutzomyia longipalpis (Sand fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC Lutzomyia; Lutzomyia.
OX NCBI_TaxID=7200 {ECO:0000313|EnsemblMetazoa:LLOJ008180-PA, ECO:0000313|Proteomes:UP000092461};
RN [1] {ECO:0000313|Proteomes:UP000092461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Jacobina {ECO:0000313|Proteomes:UP000092461};
RA Richards S., Qu C., Dillon R., Worley K., Scherer S., Batterton M.,
RA Taylor A., Hawes A., Hernandez B., Kovar C., Mandapat C., Pham C., Qu C.,
RA Jing C., Bess C., Bandaranaike D., Ngo D., Ongeri F., Arias F., Lara F.,
RA Weissenberger G., Kamau G., Han H., Shen H., Dinh H., Khalil I., Jones J.,
RA Shafer J., Jayaseelan J., Quiroz J., Blankenburg K., Nguyen L., Jackson L.,
RA Francisco L., Tang L.-Y., Pu L.-L., Perales L., Lorensuhewa L.,
RA Munidasa M., Coyle M., Taylor M., Puazo M., Firestine M., Scheel M.,
RA Javaid M., Wang M., Li M., Tabassum N., Saada N., Osuji N., Aqrawi P.,
RA Fu Q., Thornton R., Raj R., Goodspeed R., Mata R., Najjar R., Gubbala S.,
RA Lee S., Denson S., Patil S., Macmil S., Qi S., Matskevitch T.,
RA Palculict T., Mathew T., Vee V., Velamala V., Korchina V., Cai W., Liu W.,
RA Dai W., Zou X., Zhu Y., Zhang Y., Wu Y.-Q., Xin Y., Nazarath L., Kovar C.,
RA Han Y., Muzny D., Gibbs R.;
RT "Whole Genome Assembly of Lutzomyia longipalpis.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MBC1180799.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Jacobina {ECO:0000313|EMBL:MBC1180799.1};
RC TISSUE=Midgut {ECO:0000313|EMBL:MBC1180799.1};
RA Coutinho-Abreu I.V., Serafim T.D., Meneses C., Kamhawi S., Oliveira F.,
RA Valenzuela J.G.;
RT "Leishmania infection induces a limited differential gene expression in the
RT sand fly midgut.";
RL BMC 21:608-608(2020).
RN [3] {ECO:0000313|EnsemblMetazoa:LLOJ008180-PA}
RP IDENTIFICATION.
RC STRAIN=Jacobina {ECO:0000313|EnsemblMetazoa:LLOJ008180-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BicC family.
CC {ECO:0000256|ARBA:ARBA00007662}.
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DR EMBL; AJWK01027652; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GITU01012096; MBC1180799.1; -; Transcribed_RNA.
DR AlphaFoldDB; A0A1B0CTI0; -.
DR EnsemblMetazoa; LLOJ008180-RA; LLOJ008180-PA; LLOJ008180.
DR VEuPathDB; VectorBase:LLOJ008180; -.
DR OrthoDB; 2906718at2759; -.
DR Proteomes; UP000092461; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR CDD; cd22421; KH-I_BICC1_rpt2; 1.
DR Gene3D; 3.30.310.270; -; 2.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR047554; BICC1_KH-I_rpt2.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR10627:SF69; PROTEIN BICAUDAL C; 1.
DR PANTHER; PTHR10627; SCP160; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF00536; SAM_1; 1.
DR SMART; SM00322; KH; 2.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 640..703
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 574..596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 711..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..596
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 81112 MW; 698E7D519CF40FF7 CRC64;
NVLELKKKCL KIKKIIFIIL TEFLGFLFIL VDTEGRGMNK AEIFFQTIMG DTSTYICWPC
RLKIGAKTKK DPHVKIIGMP DNVLKAKERV MCSLNSRGMR VTMKLDVSYT DHSFIIGKSG
KIIKKIMEET QTHIHFPDSN RNNQNEKSNQ VSLNGALEGV VERHEPSCGM PDSESPYIKE
VQQGYEVQIA FSNKPKLHSL SVIVKGSERN CMNVKIATQL LIDKFCSYAA SRIDVMHQME
ISPQHHCIVK GKDNRNLLHI MEFTKTKIIF PDLSDANIRP LRRSQVLIYG NIEGVYSARQ
LLLGNLPVAL MFDYSNNTID PSDVAKLNNN LDVFITVRAK TRQSTLSIVI KGIEKFIKDV
YQARHDILKL DPPCIQPTIP ASYCLHLENK RLMQLPALLA LNPDTPTPSP VGYLSDKSSP
YTLFDGGSGT KSRYQTSPGN FYTFTPNELA SVGGENPVDN KYLNVPTNIS PRSVSNNTSG
YQSFSSSTNS LDHLNMYPSL NQPPSVNSSQ ERIFYGQSSR CSSSSGYGSS QFLNTSDSQS
SNINYQMKRN FDHSPIFDFN LKKLDGLRAM KTSPMGEVRT PTSTWQGLGL SRTSPMTPRD
GISGAFSADW EDTAVASPYQ LGKTCGILDS TPVQRRAQIG HHPDLQSLLT SLDLEHYINT
FVTNEIDLET FSTLTEEDLT TLGITAFGAR KKLLMAITGL AVSANSLTPH RPKFSGSAAP
GAERRTSNGV
//
