ID A0A1B0CTV0_LUTLO Unreviewed; 578 AA.
AC A0A1B0CTV0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Putative px domain-containing protein {ECO:0000313|EMBL:MBC1176257.1};
OS Lutzomyia longipalpis (Sand fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC Lutzomyia; Lutzomyia.
OX NCBI_TaxID=7200 {ECO:0000313|EnsemblMetazoa:LLOJ008300-PA, ECO:0000313|Proteomes:UP000092461};
RN [1] {ECO:0000313|Proteomes:UP000092461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Jacobina {ECO:0000313|Proteomes:UP000092461};
RA Richards S., Qu C., Dillon R., Worley K., Scherer S., Batterton M.,
RA Taylor A., Hawes A., Hernandez B., Kovar C., Mandapat C., Pham C., Qu C.,
RA Jing C., Bess C., Bandaranaike D., Ngo D., Ongeri F., Arias F., Lara F.,
RA Weissenberger G., Kamau G., Han H., Shen H., Dinh H., Khalil I., Jones J.,
RA Shafer J., Jayaseelan J., Quiroz J., Blankenburg K., Nguyen L., Jackson L.,
RA Francisco L., Tang L.-Y., Pu L.-L., Perales L., Lorensuhewa L.,
RA Munidasa M., Coyle M., Taylor M., Puazo M., Firestine M., Scheel M.,
RA Javaid M., Wang M., Li M., Tabassum N., Saada N., Osuji N., Aqrawi P.,
RA Fu Q., Thornton R., Raj R., Goodspeed R., Mata R., Najjar R., Gubbala S.,
RA Lee S., Denson S., Patil S., Macmil S., Qi S., Matskevitch T.,
RA Palculict T., Mathew T., Vee V., Velamala V., Korchina V., Cai W., Liu W.,
RA Dai W., Zou X., Zhu Y., Zhang Y., Wu Y.-Q., Xin Y., Nazarath L., Kovar C.,
RA Han Y., Muzny D., Gibbs R.;
RT "Whole Genome Assembly of Lutzomyia longipalpis.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MBC1176257.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Jacobina {ECO:0000313|EMBL:MBC1176257.1};
RC TISSUE=Midgut {ECO:0000313|EMBL:MBC1176257.1};
RA Coutinho-Abreu I.V., Serafim T.D., Meneses C., Kamhawi S., Oliveira F.,
RA Valenzuela J.G.;
RT "Leishmania infection induces a limited differential gene expression in the
RT sand fly midgut.";
RL BMC 21:608-608(2020).
RN [3] {ECO:0000313|EnsemblMetazoa:LLOJ008300-PA}
RP IDENTIFICATION.
RC STRAIN=Jacobina {ECO:0000313|EnsemblMetazoa:LLOJ008300-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AJWK01028010; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJWK01028011; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJWK01028012; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJWK01028013; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GITU01007554; MBC1176257.1; -; Transcribed_RNA.
DR AlphaFoldDB; A0A1B0CTV0; -.
DR EnsemblMetazoa; LLOJ008300-RA; LLOJ008300-PA; LLOJ008300.
DR VEuPathDB; VectorBase:LLOJ008300; -.
DR OrthoDB; 50529at2759; -.
DR Proteomes; UP000092461; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR CDD; cd06871; PX_MONaKA; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR037903; MONaKA_PX.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR22999:SF40; PX DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN; 1.
DR PANTHER; PTHR22999; PX SERINE/THREONINE KINASE PXK; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
FT DOMAIN 14..125
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 146..487
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 484..554
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..523
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 578 AA; 64944 MW; 123E3C47A19E2296 CRC64;
MAIFEKRIER KVNLDDTEEI KCFIETAQNV NGHTEYVLRV QRGPLSENSW RLLRRYNDFL
HLDKCLQISG IDLPLPAKKI LGNMHPEFIA QRRLALQEYI NHVLMNPILA SSLPTKKFVD
PDSYSTPFHD LALQNASLCL RAEGQYALGQ SLGPIGWRLR KHYFRVTMKL QAGRSSPGQT
KHLVKTISQS HARGAQSVGN GSAPSETQDL ILAWTEYGPD KYIDDREIHS TLKNLGGLQH
PYIQPLDYVT SNDNGALVIR KFVTHGTLKD MLCCVQPVNP FLTKYGNPKG RSPLPLKDVA
LYGRQILEAI RFLHSKGLPN GHVHAGNVVI VNGTARLLDI ENFILGVPAF YRPFFVQHSR
INTFEAVDVY SFGHLLYEMT MGYPLQESVA RQITDCPDSL RQLLESLLLR DSCKNGLPSL
DQVAQHAFFL EHVPNFADIL AKATRTTKPH IKWSSNAKEQ LKLAEWMSSE EEKKKIKTKA
KMEHKQSKLR QQTSLQLQNG PPVAPLTLTR SDSANSVSTS HETDSPLPPP PPPSLPNLSR
TTDDINLPGT SGERGRYALL DSICKFNKSS LRRVASDD
//
