ID A0A1B0D5V6_PHLPP Unreviewed; 752 AA.
AC A0A1B0D5V6;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=DNA repair and recombination protein RAD54-like {ECO:0000256|ARBA:ARBA00015341};
DE AltName: Full=Protein okra {ECO:0000256|ARBA:ARBA00029956};
OS Phlebotomus papatasi (Sandfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC Phlebotomus; Phlebotomus.
OX NCBI_TaxID=29031 {ECO:0000313|EnsemblMetazoa:PPAI002863-PA, ECO:0000313|Proteomes:UP000092462};
RN [1] {ECO:0000313|Proteomes:UP000092462}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Israel {ECO:0000313|Proteomes:UP000092462};
RA Fulton L., Warren W., Minx P., Wilson R., Clifton S., Abrudan J.,
RA Ramalho-Ortigao M., Lawyer P., Kamhawi S., Rowton E., Lehane M., Bates P.,
RA Valenzeula J., Dillon R., Lobo N., Collins F., McDowell M.A.;
RT "Phlebotomus papatasi, whole genome shotgun sequencing project.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:PPAI002863-PA}
RP IDENTIFICATION.
RC STRAIN=Israel {ECO:0000313|EnsemblMetazoa:PPAI002863-PA};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- FUNCTION: Involved in mitotic DNA repair and meiotic recombination.
CC Functions in the recombinational DNA repair pathway. Essential for
CC interhomolog gene conversion (GC), but may have a less important role
CC in intersister GC than spn-A/Rad51. In the presence of DNA, spn-A/Rad51
CC enhances the ATPase activity of okr/Rad54.
CC {ECO:0000256|ARBA:ARBA00024776}.
CC -!- SUBUNIT: Interacts (via N-terminus) with spn-A/Rad51.
CC {ECO:0000256|ARBA:ARBA00011467}.
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DR EMBL; AJVK01000400; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJVK01000401; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0D5V6; -.
DR EnsemblMetazoa; PPAI002863-RA; PPAI002863-PA; PPAI002863.
DR VEuPathDB; VectorBase:PPAI002863; -.
DR OrthoDB; 5480555at2759; -.
DR Proteomes; UP000092462; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.120.850; SWI2/SNF2 ATPases, N-terminal domain; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 2.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45629:SF7; DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED; 1.
DR PANTHER; PTHR45629; SNF2/RAD54 FAMILY MEMBER; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
SQ SEQUENCE 752 AA; 84069 MW; D949ADE6818E5F0C CRC64;
MRRSQAPSIK RQLGSSSSVR GSEIGNPSKC LKLSERVSAG PLREFQPQSH QQNDPDAPVP
VQNAAVRAKY AVLWNRPNNK KHKTWEGDGT LELTENTVYL RNVDGTVISS MPISAKGVEF
EDGMRLTIGS KEVEIVERLD EEVQKEEEVV QKPRNIVKPL SLSSVRKGES TGGLILPSPP
NEHQMVFNRD GKAVNPVRVV ESVAKHLRTH QKEGVFFLYE SLMGFHNPEA EYHGAILADE
MGLGKSLQNW SREVNKWLGE ERIFAFCVDG KHKVKDFSVS STMPFIILSY EMVSTQLQHL
GGMMFDVMVC DEGHRLKNSD TKIVQLLNGL DCKRRIILTG TPIQNDLHEF FCLVNFVQPD
ILGTYAQYRT KYEIPIVNSQ APSASSTFRA LGEEKVQELN EITAKVILRR TQAINQEYLP
EKEEVVVFCR PSEVQDFLQE RLLELYDESE GSVSPLKMIS LLRKICNHPA LLAAVEDEDG
LMERMSEHLP SAGELGAKDS GKLVILEGIL KSLQETGERI VVVSHSTKAL DLIEGLCQHF
EFPSCRLDGS TNSSERQKIV DRFNSHSGDE FIFLLSAKAG GTGLNLIGAS RLVLFDADWN
PATDLQAMSR IWRDGQTRNV VIYRLVTAGT IEERIFQRQI SKNSLSGFVS ESRDSVNFSD
AELRDLFALA PGSEVCLTHE ALQCPCGGAG SIPEPQEHGI SLQMSDLMQW EHHSRPIKEK
LLEELCLSHS ADDIVFLFRN PSQVPQSSSF SK
//
