ID   A0A1B0DB25_PHLPP        Unreviewed;       455 AA.
AC   A0A1B0DB25;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Equilibrative nucleoside transporter {ECO:0008006|Google:ProtNLM};
OS   Phlebotomus papatasi (Sandfly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC   Phlebotomus; Phlebotomus.
OX   NCBI_TaxID=29031 {ECO:0000313|EnsemblMetazoa:PPAI004922-PA, ECO:0000313|Proteomes:UP000092462};
RN   [1] {ECO:0000313|Proteomes:UP000092462}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Israel {ECO:0000313|Proteomes:UP000092462};
RA   Fulton L., Warren W., Minx P., Wilson R., Clifton S., Abrudan J.,
RA   Ramalho-Ortigao M., Lawyer P., Kamhawi S., Rowton E., Lehane M., Bates P.,
RA   Valenzeula J., Dillon R., Lobo N., Collins F., McDowell M.A.;
RT   "Phlebotomus papatasi, whole genome shotgun sequencing project.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:PPAI004922-PA}
RP   IDENTIFICATION.
RC   STRAIN=Israel {ECO:0000313|EnsemblMetazoa:PPAI004922-PA};
RG   EnsemblMetazoa;
RL   Submitted (AUG-2022) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC       {ECO:0000256|ARBA:ARBA00007965}.
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DR   EMBL; AJVK01000653; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A1B0DB25; -.
DR   EnsemblMetazoa; PPAI004922-RA; PPAI004922-PA; PPAI004922.
DR   VEuPathDB; VectorBase:PPAI004922; -.
DR   OrthoDB; 517168at2759; -.
DR   Proteomes; UP000092462; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR002259; Eqnu_transpt.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR   PANTHER; PTHR10332:SF10; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1, ISOFORM A; 1.
DR   Pfam; PF01733; Nucleoside_tran; 1.
DR   PIRSF; PIRSF016379; ENT; 1.
DR   PRINTS; PR01130; DERENTRNSPRT.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ   SEQUENCE   455 AA;  50811 MW;  93C93413778182DB CRC64;
     MDHSINSRPL LQPSDSDFGE SDDTRASNDE VEIRSETKNE PTDRLNIIYM IFYLLGMTTL
     LPWNFFITAE NYWMFKFRNV TGNDTDVLTP IQRTFTSDLS VSSAVPNTVF LVLNAFLSHR
     IPLKLRMMGS MGIIFVLFIF TTVFVEVDTD SWQRAFFAIT ITTVVVMNIA AAILSGGLFG
     IAGQFPSEYM TAVVSGQALG GIFAALCEVI SLTFGASPNT TALVYFSVAI VVMIISLLAY
     FLMSRTIFFK FYTSNRSSVT PRLQDEAHLL GEPPIAPDFR HILRKIWLYG FSEWFVFVVT
     LSVYPAVTVL VTSENHGNGH LWNDVFFTTV VNYLVFNSGD YLGRIIAGLF EWPQNRPRLV
     AFFTLIRAGF IPIFLMCNST PRENLPIIIH SDIVFILLMC IFALTNGYIA NIALLCAPKI
     VANHEKEMAA SMMAAFLGIG LAFGSGFGLL FVQIL
//