ID   A0A1B0DMC0_PHLPP        Unreviewed;       515 AA.
AC   A0A1B0DMC0;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:PPAI009510-PA};
OS   Phlebotomus papatasi (Sandfly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC   Phlebotomus; Phlebotomus.
OX   NCBI_TaxID=29031 {ECO:0000313|EnsemblMetazoa:PPAI009510-PA, ECO:0000313|Proteomes:UP000092462};
RN   [1] {ECO:0000313|Proteomes:UP000092462}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Israel {ECO:0000313|Proteomes:UP000092462};
RA   Fulton L., Warren W., Minx P., Wilson R., Clifton S., Abrudan J.,
RA   Ramalho-Ortigao M., Lawyer P., Kamhawi S., Rowton E., Lehane M., Bates P.,
RA   Valenzeula J., Dillon R., Lobo N., Collins F., McDowell M.A.;
RT   "Phlebotomus papatasi, whole genome shotgun sequencing project.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:PPAI009510-PA}
RP   IDENTIFICATION.
RC   STRAIN=Israel {ECO:0000313|EnsemblMetazoa:PPAI009510-PA};
RG   EnsemblMetazoa;
RL   Submitted (AUG-2022) to UniProtKB.
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DR   EMBL; AJVK01016734; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJVK01016735; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A1B0DMC0; -.
DR   EnsemblMetazoa; PPAI009510-RA; PPAI009510-PA; PPAI009510.
DR   VEuPathDB; VectorBase:PPAI009510; -.
DR   OrthoDB; 2898719at2759; -.
DR   Proteomes; UP000092462; Unassembled WGS sequence.
DR   GO; GO:0004383; F:guanylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   Gene3D; 3.90.1520.10; H-NOX domain; 1.
DR   Gene3D; 3.30.450.260; Haem NO binding associated domain; 1.
DR   InterPro; IPR038158; H-NOX_domain_sf.
DR   InterPro; IPR011644; Heme_NO-bd.
DR   InterPro; IPR011645; HNOB_dom_associated.
DR   InterPro; IPR042463; HNOB_dom_associated_sf.
DR   InterPro; IPR024096; NO_sig/Golgi_transp_ligand-bd.
DR   PANTHER; PTHR45655; GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2; 1.
DR   PANTHER; PTHR45655:SF6; HEAD-SPECIFIC GUANYLATE CYCLASE; 1.
DR   Pfam; PF07700; HNOB; 1.
DR   Pfam; PF07701; HNOBA; 1.
DR   SUPFAM; SSF111126; Ligand-binding domain in the NO signalling and Golgi transport; 1.
PE   4: Predicted;
FT   DOMAIN          80..198
FT                   /note="Heme NO-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07700"
FT   DOMAIN          252..403
FT                   /note="Haem NO binding associated"
FT                   /evidence="ECO:0000259|Pfam:PF07701"
SQ   SEQUENCE   515 AA;  57857 MW;  6D878906450AF0ED CRC64;
     MACPFVHTIG KQHSVADSTT WNLEDDLTDL PDDALTLTHL NAAIQLLTAP SNENINQAVK
     SVIKKYSDRW PGIINLKIDS DSFSMYPNYD YLADIQDSIV GMDEAAASEI LILIGEELID
     TCCVGIIERA FRCLGGDLQE FLGSLDGVHD VLKLQEANIS DTGFVCAGEG ELIFTSERPV
     ISWLLLGSLR QLAKILYGIE DAQITMEPID GDVKRYRYLF DVGPSLGKRQ LEEPIQLKAR
     KRASVSTAAE DLKMNATTFC KAFPWHFVMN ENLELLQLGH GFNRLFRQSL SLYGRHATTY
     FRFKRPRGLS LNFQEIRKHT HTPFLLAIRS QVCRRDSTMT GLEIKGQMVY CAETNTLLFI
     GSPFLDGLEG LTCNGLFISD IPLHDATREV ILVGEQARAQ DGLRRRIMTG PMESTGHTVC
     ISNGLHFVHI EKTTELIKVP VETLEHIDDH DGCCSGANTR ESYNIAEEHR DVWMRLGFNG
     ITSPERLCNL CWEYQLQETH VLLTLFGYGS ITLFD
//