ID   A0A1B0EUV8_LUTLO        Unreviewed;       784 AA.
AC   A0A1B0EUV8;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Putative host cell transcription factor hcfc1 {ECO:0000313|EMBL:MBC1172535.1};
OS   Lutzomyia longipalpis (Sand fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC   Lutzomyia; Lutzomyia.
OX   NCBI_TaxID=7200 {ECO:0000313|EnsemblMetazoa:LLOJ004789-PA, ECO:0000313|Proteomes:UP000092461};
RN   [1] {ECO:0000313|Proteomes:UP000092461}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Jacobina {ECO:0000313|Proteomes:UP000092461};
RA   Richards S., Qu C., Dillon R., Worley K., Scherer S., Batterton M.,
RA   Taylor A., Hawes A., Hernandez B., Kovar C., Mandapat C., Pham C., Qu C.,
RA   Jing C., Bess C., Bandaranaike D., Ngo D., Ongeri F., Arias F., Lara F.,
RA   Weissenberger G., Kamau G., Han H., Shen H., Dinh H., Khalil I., Jones J.,
RA   Shafer J., Jayaseelan J., Quiroz J., Blankenburg K., Nguyen L., Jackson L.,
RA   Francisco L., Tang L.-Y., Pu L.-L., Perales L., Lorensuhewa L.,
RA   Munidasa M., Coyle M., Taylor M., Puazo M., Firestine M., Scheel M.,
RA   Javaid M., Wang M., Li M., Tabassum N., Saada N., Osuji N., Aqrawi P.,
RA   Fu Q., Thornton R., Raj R., Goodspeed R., Mata R., Najjar R., Gubbala S.,
RA   Lee S., Denson S., Patil S., Macmil S., Qi S., Matskevitch T.,
RA   Palculict T., Mathew T., Vee V., Velamala V., Korchina V., Cai W., Liu W.,
RA   Dai W., Zou X., Zhu Y., Zhang Y., Wu Y.-Q., Xin Y., Nazarath L., Kovar C.,
RA   Han Y., Muzny D., Gibbs R.;
RT   "Whole Genome Assembly of Lutzomyia longipalpis.";
RL   Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:MBC1172535.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Jacobina {ECO:0000313|EMBL:MBC1172535.1};
RC   TISSUE=Midgut {ECO:0000313|EMBL:MBC1172535.1};
RA   Coutinho-Abreu I.V., Serafim T.D., Meneses C., Kamhawi S., Oliveira F.,
RA   Valenzuela J.G.;
RT   "Leishmania infection induces a limited differential gene expression in the
RT   sand fly midgut.";
RL   BMC 21:608-608(2020).
RN   [3] {ECO:0000313|EnsemblMetazoa:LLOJ004789-PA}
RP   IDENTIFICATION.
RC   STRAIN=Jacobina {ECO:0000313|EnsemblMetazoa:LLOJ004789-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   EMBL; AJWK01014976; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; GITU01003832; MBC1172535.1; -; Transcribed_RNA.
DR   AlphaFoldDB; A0A1B0EUV8; -.
DR   EnsemblMetazoa; LLOJ004789-RA; LLOJ004789-PA; LLOJ004789.
DR   VEuPathDB; VectorBase:LLOJ004789; -.
DR   OrthoDB; 5477547at2759; -.
DR   Proteomes; UP000092461; Unassembled WGS sequence.
DR   Gene3D; 6.10.250.2590; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR043536; HCF1/2.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   PANTHER; PTHR46003; HOST CELL FACTOR; 1.
DR   PANTHER; PTHR46003:SF1; HOST CELL FACTOR; 1.
DR   Pfam; PF01344; Kelch_1; 1.
DR   Pfam; PF13415; Kelch_3; 2.
DR   Pfam; PF13854; Kelch_5; 1.
DR   SUPFAM; SSF117281; Kelch motif; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REGION          392..426
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        394..422
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   784 AA;  84928 MW;  6D653944A46D033E CRC64;
     MACSAFKWRK VLNSTGPQPR PRHGHRAVAI KELMVVFGGG NEGIVDELHV YNTVTNQWYV
     PATKGDVPPG CAAYGFVVDG TKILVFGGMV EYGKYSNDLY ELQATKWEWR KLKPSPPDKG
     IVGPCPRLGH SFTLVGDRVF LFGGLANESD DPKNNIPKYL NDLYVLNIRT EPMTWEVPQT
     IGERPPPRES HTCVLYTDKS RRNFLVIYGG MSGCRLGDLW LLDTDSMTWS RPTTAGNPPL
     PRSLHTSTLI GHRMFIFGGW VPFIPDEGKV VAEKEWKCTN TLACLNLESM TWEELSIDMG
     VENIPRARAG HSAVGIQSRL YVWSGRDGYR KSWNNQVRVC CKDLWYLEVE VPPPATRVAL
     IRASTKSLEM CWGAVPTAQC YLLEIQKIDQ APKSPAQAPP PPALAISPPK LQPTPPRKPP
     ENIQGQPVRV VAPVGVRLPT QQQIIRKPTP VAAASITGKQ IIIQKPTVAG GSSTIQPQIS
     QGTVAGAKAQ IVKLVKTSQG MAVQTLPKMT VVSGASVISG NSATTKTPIM GNVVKIVSSM
     DKFVLKNATP LTASAGKILI ANQQQSAIRP NQQIIVVSSS TGARQLQVTP AMPVTIPATG
     VSPATSATAS GISTPTGKVL PQRPITITMQ NTKTPGQVIH VPPKALQLAG GKAITVQLPK
     TMTIVQPSGS SGQSERIVML PKAVARPPED PDTSKVEQLD GAWDELVKFV GREGHPPRIG
     LMGGAPPDEQ QQDIFQQEDA NETDVADVVE SQDISKDVVE EMGKEVFSDI PGGMMWSCKC
     THIN
//