ID A0A1B0FEN4_GLOMM Unreviewed; 2372 AA.
AC A0A1B0FEN4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
OS Glossina morsitans morsitans (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=37546 {ECO:0000313|EnsemblMetazoa:GMOY002070-PA, ECO:0000313|Proteomes:UP000092444};
RN [1] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RG International Glossina Genome Initiative W.H.O.;
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:GMOY002070-PA}
RP IDENTIFICATION.
RC STRAIN=Yale {ECO:0000313|EnsemblMetazoa:GMOY002070-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; CCAG010014783; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 37546.A0A1B0FEN4; -.
DR EnsemblMetazoa; GMOY002070-RA; GMOY002070-PA; GMOY002070.
DR VEuPathDB; VectorBase:GMOY002070; -.
DR PhylomeDB; A0A1B0FEN4; -.
DR Proteomes; UP000092444; Unassembled WGS sequence.
DR GO; GO:0043232; C:intracellular non-membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd00176; SPEC; 2.
DR Gene3D; 1.20.58.60; -; 4.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR PANTHER; PTHR11915:SF442; ALPHA-ACTININ, SARCOMERIC-RELATED; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR SMART; SM00033; CH; 2.
DR SMART; SM00150; SPEC; 5.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 6.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..90
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 101..204
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 245..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1689..1713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1756..1784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1848..1900
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 454..484
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 593..620
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 764..791
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 890..940
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1374..1401
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1904..1934
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2324..2351
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 248..267
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1756..1777
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1848..1870
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1878..1893
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2372 AA; 272721 MW; C62421161457E36F CRC64;
MKTQCAPVND LFLDLRDGNR LLALLSVLTD TQLKPEKGRM RVHHINNLNK VLQVIHEHGI
KLVNISSDDI VGGNPKLTLG LIWLIALEFN GQNLVKTHSS NGVEKSLLAW ARQFTEPRGL
HLHDFSNSWS DGRAFLMILD AHLDGIDLST ALTKHPLARL KTAFDLAHTY FKIEKLLDPE
DVHTHKPDKK SIQMYVMCLY HAMEIRKSLD ASDSMTEALF DDKAQEVYPS SAPINITDLD
EVPLDSNEEA SSEVSSTPLS ATDSGCKTKY NSDTMRSIMD IEMDRPKSCQ LIKDDKSRPH
STATNVSVEI TTYQTALEAV LTLLLEDEQI LSQDLREPQD FHSAKMQFHD NEQFMLKLTE
HQQYVGEALE EGSNLINESQ KNSGLSVEDQ NEIRQQMVLL NERWETLRLK ALDVQAKILT
RLANFQTQQI EKLRTFLTHI EDRISHMTAI GPTLNEVQAQ LDEARQLKVD LQNQQDLVDS
LSNMVVIVND ESGNFNDLED KLSALGERWS HVVKWSDLRL EKLQQYKTIS RWLDSREQDL
KNMESRDVVD LGTITKRMND LNYCAKDLLE LERYLIDLRQ MVAATLQEGD DKGERVLMQL
ENFEDRLDAL KQMVEVQTVR IEQKGFKFGR NRASYDDSRV VRPDGWLDYQ MIIKFGEDDI
EDDNDENSED DKNCLLAEGT SVACKKRKLR NTENFYLLEG KILDAFGFVD DSEERLLTMQ
RQSLRNQTDI LNGLEQELTH RLTSAKDLRD LYEMCEKEDV SRNMIMEASQ IKQIEERYEH
LKKRIERQRL ETLYMLKKEK FYNSLTGFKL VLADSRDWYQ QHAGTASKQD LEQRLSHMES
LSSEIASAKE TTGTLADDLI EWKQDFNLFY ESWNDMKKAV LALIEEKGGL DEINQRLEIL
EEFLDRANKV KVLISALEPM ELQLKKLNSL HNESEALKLE YEFIYVRRAD AVSTEFAEAW
AKIPEQINER IIKQTTAIEN LNHFTAEYNA IMAILRKLES NFKEDENLSD DNSSRKSDID
NNMELRKVEI DVISARNFSE IIIKDAEPEH RNHLVAQIKE LNEFFQQVQN LYKETLQKRV
VVQAKTEEIF QRLSQTDEWL NELEANTPKT SVAEIKNSNE LFHIKCKFQA LKETCEKETA
SFRELNELGG EVLLQIDELK TKGVEQVQQK YNMLAKKLTR LNARWTEVTT LVYKRTALLE
HISIQLGEFK KFMVSETGYL DRLENKMRST PENADAEEII EELDDLENVL RGHSDDWLEK
IQEIGQELIA HEFMADSIRQ EIDAIADRWY QLQHKAKQRV EVLEREVSEA KQSEKCIVQF
EAWLTRVDEI LSEHLENDVT IEDLPDDFQR LSQEFEENEK CFQEIDDLIA EHQRNGKTEA
ANRLQEQLNL LEMRFKSCQL KLNKCTAPQP AYESRLNRAV AELRNVERST LVLDVASAGP
STVQIQYQKC LQIYRTLSEV KPEIESTIKI GRKVCEDKFT KSPKQLSQRI DALKHLYNAL
GENVTQSKIF LESLIKLAHQ LEDCFDIADH LIKKFECPQE IHDRNSLFLE FEDILQKSED
IYEEYSKSCD QVCMDETRQR IDDLKATYLK LTSADVIKRL TEMKSTLQNL DNISLDTLRA
MEHDLKQISV PSNPEIEKLQ QQVIAIVVDA LKTKYEQASS LENLNETDKL NIPVTEDTEI
VVVSNTVRQR RARTPSSNET VPSKDNVQSS PTTQNLQVGC VENNIECQQQ QAQVLPDLLP
PQTFRLAETS ALFSQISKNP QSTTETATNS SVNGQKLPLK RKNADPQAQM VEVKVKNINN
NKMSVHMAND LEPQQGEIVD TVNILESVEP FVPEYVETVQ IIDVSEDSDS SVRLDAEGRD
LKKSKSKRSL CESPRTPLIE ETETEKESEV ELRPTDANNT NTPILRVEKQ RISFEEKRKR
MESERDILRD SEEETDMATT STPSYVKPKV KRWRQLHAAT DELDNSMTDA MVRDSFYNPD
KELSFDVEPL VFSDDEDIPR FSMEMTQPID SDSDTSRIET PSAKKPNTFI NKILPQSPSL
DDSNLSLKSA LTEIINTKQL LSLEQRVLEF ESKAKNMIHR LEKTKEKIER CCEGERAVED
LKMLIAPDAA TLISQGDSLV LETHGKQGNI SRVVMKNQII LREKFREVQQ TKPKVPVSDS
LTLTSQTSRL DGNSIKNINL EELISKGLKR INDLIEKPVE SKSITELEKR LSEINDRRDD
LKLIVNAIGK SEQMPKVSCT TMNDIEQIKS NLQNHADHIE LSLTELKSLS KLNKSLNVGK
DYIDEPSGSG ALAGGFDKSV LQISDWLTWE QNMIKIQSVP VDNIDAIRMA IEKQEKILRE
LKTKKPQLNE LVHTAEILKG DVKRQQLQEK GK
//
