ID A0A1B0FNH0_GLOMM Unreviewed; 2009 AA.
AC A0A1B0FNH0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Down syndrome cell adhesion molecule-like protein Dscam2 {ECO:0008006|Google:ProtNLM};
OS Glossina morsitans morsitans (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=37546 {ECO:0000313|EnsemblMetazoa:GMOY005407-PA, ECO:0000313|Proteomes:UP000092444};
RN [1] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RG International Glossina Genome Initiative W.H.O.;
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:GMOY005407-PA}
RP IDENTIFICATION.
RC STRAIN=Yale {ECO:0000313|EnsemblMetazoa:GMOY005407-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CCAG010010693; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CCAG010010694; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CCAG010010695; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CCAG010010696; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CCAG010010697; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 37546.A0A1B0FNH0; -.
DR EnsemblMetazoa; GMOY005407-RA; GMOY005407-PA; GMOY005407.
DR VEuPathDB; VectorBase:GMOY005407; -.
DR PhylomeDB; A0A1B0FNH0; -.
DR Proteomes; UP000092444; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd00063; FN3; 6.
DR CDD; cd20956; IgI_4_Dscam; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 16.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF39; FI24025P1; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 5.
DR Pfam; PF07679; I-set; 6.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 9.
DR SMART; SM00408; IGc2; 8.
DR SUPFAM; SSF49265; Fibronectin type III; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 9.
DR PROSITE; PS50853; FN3; 6.
DR PROSITE; PS50835; IG_LIKE; 8.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1581..1602
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 162..248
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 257..349
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 355..451
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 455..545
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 549..639
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 644..730
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 734..830
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 835..953
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 958..1062
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1067..1164
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1168..1267
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1267..1354
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1357..1450
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1454..1557
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1745..1894
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1763..1820
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1827..1874
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2009 AA; 221895 MW; FFE755742D120ACB CRC64;
MFRKIAGNGT LYFPPFLSQY YRTDVHETTY RCRATNEAGT ILSRNVRVQA VVRRQFHVHV
ESTEVFLGNS ALIKCAIPDY VRTYVKVASW QRGDEILLPD LSDVAGRYVV LSTSGDLYVR
SVRTEDSLVK YSCLATNTLN GDRQRSDAVM LQVKELSQNL APRTTQKPVM DIHVERGNDV
HMPCNIQGNP FPIFTWYRVS DSSALYPIPS SQRIILSRTL LLIKNADERD AGKWICQASN
QFGEQRVEIR LFVNSYVSVH ILPQVQIVNS GGIAIFNCST TGSAIDNIEW LHNGKPLQED
NALTTGRDNL HFLSKASLLI QNVGRGDRGV YQCLVENHKS SAQAMAELKL GDTVPELIYT
FIEQNVRPGP LISLKCSASG SPPPQFSWLL DSQPIMDVSL HHRFAIGQFV DMSGDVISHL
NISHVRPDDG GLYKCIATNS MGSVEHSARL NVYGPPYVRA IGPLKAVAGV DVTVHCPFSG
YPIEQIRWEK GHHELTSNSH YSLAPVQQGG YIVIKNVEPT RDQGMYTCIV KSRAGEEARR
DMQLNVNSPP VIEPFKFPKN LQEGGRAQIT CAVSSGDMPI YFSWKKDDMS IPTTLQITEK
KEEFFSLLVF KDISAKHSGK YTCYASNAAA KVNFTAELQV RVAPRWSFEP MDTAIMLGNT
ISINCEAEGY PIPAITWFKG QDKLNKDFKP LNMRNHSLVL NFATDIDEGY YMCQATNDIG
AGLKKVIRIN VNEPARFEQP ARNVSSRRND AVTVDCQAKG DEPITIAWTH NNGRIDLNNF
RFSIAEMKTE KGVDSQLTIA RSDRHDSGIY KCIAENPYGR AEQIIYLAVQ ERPDTPSNLE
VFEVGSRTVK LSWRRPFDGN SPVLSYLVQY QPLKYLQSHA ALNLAGGDWS GPNIINATLP
STSVSKSYDS DLRESAIVAG LTPATTFLIR MQAINEIERS TFTDPIVLKT QEEAPTEAPS
NVQVQTGGER ELIVTWQIPP RESWNGELIG YTVNCTEEKQ NINYISVVNN SLKSVIVSGW
ATTKATLRGL RKYTRYAVTV RALNSFGSGP WSAPIFGTTA EGVPEAAPQH VNCTALSSQS
LKISWLEPPL QFHGGIIQGY KILYRPIVNQ IDFPAKMEVK RTSNLETYLH TLHKATNYSL
RVLAYTATGD GVASQALYCQ TEDDVPDAPA SIKAAALTAD SILISWLPPR NRNGIITHYT
VYSREAGRKG PAKSYMVRVD ENGYPVTYEA RGLAENQMYE FWVSASTSVG EGEPTSVVAQ
ATNTRAPARI ASFSQVVRKA VGTSLVLECL AVGNPTPRAR WLTRDRPVTF SPFYEVTADG
NLKIHRVEGS LSGNYTCTAN NLFGNDEIQY QVIAMKQPAA PQIIVQYASA DSIRVSWDPP
DDGGAPLQGY SIFYRIAGET WSQAELMPEN NAYTITQLKC GNQYIIKMSA HNLVGDGVAS
EEINVWTKGK ASQAPNGNEL IVTNASCVNL KLSAWHNGGC PIHHFSIEHR PLGDIRWTVV
TSDISNAEEN RENLIFCDFL PAKWYQLRIS ATNDAGKTTE HYHFATTNID GVTIPPPSVF
PSESDLMNNL INATNPTNGD WFSTLIVIVI ITVAMITVGL TIKHRRTLCG PMSEGYESRA
LPTEYKEDHD NHRNQQVYSA SPVKTVDKAN ESEMYEISPY ATFSVNGGRT GAPAKTSTRG
MAASPLDYTM QFKTFGHPEG ENLNATAYPL LPSSGFGHIK SKSSWHKQRY YNTDDDSTLS
KSLTLVAGSQ TGHTKKSGRS DGGRNNSKSA GGTTGTTSSA GAGGGHCESE SDTSISPSTE
FSNMPTYRVP CKSSRNSDGR SGVDMFRPDS STESNNDQSS PVERRANSQR FTAGSGASGG
KDNNTTSSSS SSADKRIHPR NRKHQGQQQQ SQIIVKDSLE RRLRSGSNNS LNSEINNSET
SASIAATIAA MTGVNGNMGF RPPTGFMDSR EFSEAECDHE QRALDLEVQR VMENTDGQLS
KVDREELSSL LARYHEKKEQ ERQEFTIHV
//
