ID A0A1B0FQH4_GLOMM Unreviewed; 1804 AA.
AC A0A1B0FQH4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Laminin subunit beta-1 {ECO:0008006|Google:ProtNLM};
OS Glossina morsitans morsitans (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=37546 {ECO:0000313|EnsemblMetazoa:GMOY006162-PA, ECO:0000313|Proteomes:UP000092444};
RN [1] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RG International Glossina Genome Initiative W.H.O.;
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:GMOY006162-PA}
RP IDENTIFICATION.
RC STRAIN=Yale {ECO:0000313|EnsemblMetazoa:GMOY006162-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR EMBL; CCAG010002563; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 37546.A0A1B0FQH4; -.
DR EnsemblMetazoa; GMOY006162-RA; GMOY006162-PA; GMOY006162.
DR VEuPathDB; VectorBase:GMOY006162; -.
DR PhylomeDB; A0A1B0FQH4; -.
DR Proteomes; UP000092444; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd00055; EGF_Lam; 13.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 11.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013015; Laminin_IV_B.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR PANTHER; PTHR10574:SF448; WING BLISTER, ISOFORM B; 1.
DR Pfam; PF00053; Laminin_EGF; 13.
DR Pfam; PF21199; LAMININ_IV_B; 1.
DR Pfam; PF00055; Laminin_N; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 9.
DR SMART; SM00180; EGF_Lam; 13.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 13.
DR PROSITE; PS01248; EGF_LAM_1; 5.
DR PROSITE; PS50027; EGF_LAM_2; 9.
DR PROSITE; PS51116; LAMININ_IVB; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 61..298
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 299..362
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 426..485
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 486..536
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 575..799
FT /note="Laminin IV type B"
FT /evidence="ECO:0000259|PROSITE:PS51116"
FT DOMAIN 805..852
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 853..898
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 899..948
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1060..1110
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1111..1158
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1159..1205
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT COILED 1271..1333
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1719..1791
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 328..337
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 456..465
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 508..517
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 520..534
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 805..817
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 807..824
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 826..835
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 853..865
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 855..872
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 874..883
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 918..927
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1083..1092
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1111..1123
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1113..1130
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1132..1141
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1159..1171
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1161..1178
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1180..1189
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 1804 AA; 200930 MW; 97A2052A8424ACD3 CRC64;
MIKLFCGGIA IGSRFSLITI ISFIFLFSFI HVLPINAQRH AGRRDRPRNP PRTYVKTHPC
ERSSCYPATG NLLIGRENRL TASSTCGLHS PERFCILSHL QDKKCFLCDT REETRNDPYK
NHRIGQIIYK TKPGTNIPTW WQSENGKENV SIQLDLEAEF HFTHLIMSFT TFRPAAMFIE
RSFDFGETWQ VYRYFAYDCA DSFPGVPTIL RNISDVVCTS RYSNVEPSRN GEVIFRVLPP
NINVSDPYAA HVQNMLKVTN LRVIFQKLHK LGDNLLDNRL ENEEKYYYGI NYMVVRGSCQ
CYGHASQCLP LDTAEHNELD MVHGRCQCTH NTRGLNCETC EDFFNDLPWK PALGKQTNAC
KKCECNDHAV SCHFDEAVFE KSGRISGGVC DNCLHNTMGQ HCEECMAFFY RDPSEDIRSP
YVCKPCDCDP IGSLDEGICD SVNDPDNGIE AGSCHCKTNV RGRRCDTCKD GFWNLDPENP
EGCEACSCHT LGTVDNTGCN MFTGECTCKR LVTGKDCNQC APETFGLSES EDGCLPCDCD
AGGSYDNFCD VITGECRCRP HMTGRACSLP KQNYFIPQLH IVHEAEIPDL CISNVNNANC
STVPFQPSVD RTPDWTGIGF VRVPENSELV ITVNDIPRSM PYDVLIRYQT TSRGDWEDAF
ITLVRPDEVD PKGDCASMVP YGSSARETRI PFLLSDHERQ VLAMREICLE AGKVYKFKIH
FERRRHNEDN PTATILVDSL TLIPRIELTT VFTGSPIADS RRDEYYQMGC NQSLYDIRYR
PYASERCKEL ENYVSMVIYD GASMCNCNPT GSLSKECDAH GGFCQCKPNV VGRQCDQCAP
GTYGFGPEGC KACDCNSIGS RDNNCDVVTG QCACHPNTYG RECDQCQPGF WNFPNCQACE
CNGHAQQCDA RTGQCLNCMD FTTGYACDAC LNGYYGNPFL GSEIGCRACR CPDTMASGNA
HADGCSLDLR NNNMICHCQE GYDGSRCDVC ADNYFGDAEE PGGSCQKCNC SNNIDIYDTG
NCDRRMGNCI KCLYDTTGDH CELCRDGYFG DALQQNCVPC DCDFLGTNKT IQYCNRFSGQ
CPCLPNVMGL RCDECAENHW KIASGEGCEA CECDPIGALS EQCNRYDGQC DCKSGFGGRA
CNQCQTNYWG NPNEKCQPCD CDPYGSADFQ CDRETGQCVC HEGIGGYKCN ECARGYLGES
PHCMPCGECF NNWDLILKEL EEATMHAIQR AKEIKLIGAT GAYTAEFNAL DTKLQNIRNL
LQNTSVSLQD MDTLDSEVSE LKRKLSAAHQ KLIDTESNLD GIYSSLSLSA AELETLQNQS
ALVKKLSQEL KENGIQLQES NIEGALNLTR NAYDRVLDLT NVKNEAEDYA ASTDRNCKRV
ETLANKMKDE SSAVTANDDL IDQYRSELSA LTAMIPELNN EVCDRKGDPC DNICGGAGCG
TCGGLSCERG ALTRTEKALK VAKDTELEIK EKKDQADQTI RSLFQAKVNA SDAYQKAKDA
HEDAETYLNR TELNKKRGED MIQNLTEFLE NNVALPTETK ELAQKTLTLD LTLDPLEIQT
LGGKINDAVS SLKNVEGIIY NTRSDLAKVN ELQAKANVTK ETANEILATA NTVVENLNDA
DLSQGKAQEA ILEANSNIEL AAKDLDQIDA ETSQAEAPAN ITAQQVEELA KKVNYLQKNI
LKNELDAKDV KNEADSVKLL SQNAHGDALK LQYSSSAANE TLTNRARQSE SARERAKQLL
QRASKLTVDT KEKLRELKFM HETYDEKNDK LQQLQEALKP LHEELAQHLK NIQMNADRYR
QCSS
//
