ID A0A1B0FV11_LUTLO Unreviewed; 549 AA.
AC A0A1B0FV11;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 16-JAN-2019, sequence version 2.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Ionotropic glutamate receptor C-terminal domain-containing protein {ECO:0000259|Pfam:PF00060};
OS Lutzomyia longipalpis (Sand fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC Lutzomyia; Lutzomyia.
OX NCBI_TaxID=7200 {ECO:0000313|EnsemblMetazoa:LLOJ001956-PA, ECO:0000313|Proteomes:UP000092461};
RN [1] {ECO:0000313|Proteomes:UP000092461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Jacobina {ECO:0000313|Proteomes:UP000092461};
RA Richards S., Qu C., Dillon R., Worley K., Scherer S., Batterton M.,
RA Taylor A., Hawes A., Hernandez B., Kovar C., Mandapat C., Pham C., Qu C.,
RA Jing C., Bess C., Bandaranaike D., Ngo D., Ongeri F., Arias F., Lara F.,
RA Weissenberger G., Kamau G., Han H., Shen H., Dinh H., Khalil I., Jones J.,
RA Shafer J., Jayaseelan J., Quiroz J., Blankenburg K., Nguyen L., Jackson L.,
RA Francisco L., Tang L.-Y., Pu L.-L., Perales L., Lorensuhewa L.,
RA Munidasa M., Coyle M., Taylor M., Puazo M., Firestine M., Scheel M.,
RA Javaid M., Wang M., Li M., Tabassum N., Saada N., Osuji N., Aqrawi P.,
RA Fu Q., Thornton R., Raj R., Goodspeed R., Mata R., Najjar R., Gubbala S.,
RA Lee S., Denson S., Patil S., Macmil S., Qi S., Matskevitch T.,
RA Palculict T., Mathew T., Vee V., Velamala V., Korchina V., Cai W., Liu W.,
RA Dai W., Zou X., Zhu Y., Zhang Y., Wu Y.-Q., Xin Y., Nazarath L., Kovar C.,
RA Han Y., Muzny D., Gibbs R.;
RT "Whole Genome Assembly of Lutzomyia longipalpis.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:LLOJ001956-PA}
RP IDENTIFICATION.
RC STRAIN=Jacobina {ECO:0000313|EnsemblMetazoa:LLOJ001956-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
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DR EMBL; AJWK01006521; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0FV11; -.
DR EnsemblMetazoa; LLOJ001956-RA; LLOJ001956-PA; LLOJ001956.
DR VEuPathDB; VectorBase:LLOJ001956; -.
DR OrthoDB; 3677745at2759; -.
DR Proteomes; UP000092461; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050906; P:detection of stimulus involved in sensory perception; IEA:UniProt.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR PANTHER; PTHR42643; IONOTROPIC RECEPTOR 20A-RELATED; 1.
DR PANTHER; PTHR42643:SF37; IONOTROPIC RECEPTOR 84A; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..549
FT /note="Ionotropic glutamate receptor C-terminal domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017692293"
FT TRANSMEM 314..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 346..450
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00060"
SQ SEQUENCE 549 AA; 63081 MW; 5D2658F393C958B9 CRC64;
MKVHTIFILL CILWGMAFSS HPFPSNHLLL NYFKGRNVLS VTYYSCRSDS HKLTREFNKE
NVPVIVLTNT EVRPVLLTSK NGVIVDLSCD FVPDLLDFSL QNYLFREIIS WIFIGEDGTT
NYELLIESFI PISSEVVIFT PIFNDPTSSW NIFSIYKVTE KSEMNFTPIL YTSEDNVVSL
TSLYETTKRK NLNGSKIRAT IAFHYPHRLT KYDDLRMNYI DTATKTTYQF LMNLATDLNF
TYDLTQTDSY GFLKNGSFTG LMGHLERKEI EVGIASSFLR KDRLPIVEYI SESFIIRSPL
IFRQPSLASV SNIYALPFGL SVWVSLIALI VILILAQILL IAMPIMRNEA SLLDSFSIVL
SAVSQQGFSR DSFRFSWRIL HFITFLSFYF LFSSYSANIV ALLQSPSNAL KTISDVTHSN
LKVQVQNKEY NPVLYEESTD PAVIELFLKK IKPFGAKGYE DAEVGVKNIL TGRFAYQIEA
HTAYKIISNT YTESEKCGLK EIESVKIPRH SIPIVRNSSY RSIFRERLMW QRETGHFDVN
IKRWVTQKT
//
