ID A0A1B0G119_GLOMM Unreviewed; 546 AA.
AC A0A1B0G119;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
OS Glossina morsitans morsitans (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=37546 {ECO:0000313|EnsemblMetazoa:GMOY006958-PA, ECO:0000313|Proteomes:UP000092444};
RN [1] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RG International Glossina Genome Initiative W.H.O.;
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:GMOY006958-PA}
RP IDENTIFICATION.
RC STRAIN=Yale {ECO:0000313|EnsemblMetazoa:GMOY006958-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR EMBL; CCAG010008718; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0G119; -.
DR STRING; 37546.A0A1B0G119; -.
DR ESTHER; glomm-d3tm45; Carb_B_Arthropoda.
DR EnsemblMetazoa; GMOY006958-RA; GMOY006958-PA; GMOY006958.
DR PhylomeDB; A0A1B0G119; -.
DR Proteomes; UP000092444; Unassembled WGS sequence.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF408; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Serine esterase {ECO:0000256|ARBA:ARBA00022487};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 19..546
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5008446006"
FT DOMAIN 22..539
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 546 AA; 62622 MW; E7788F96086C34D8 CRC64;
MILLSSISFI YFALLCKGEQ TIQIDTDLGE IKGIQMTSRL GEKFWAFRGI RYAKPPIGEL
RFQSPQPIET WKPQIYDATT DGPICSQGYG SIDLISEDCL CLNVYTRDLK NLKPVLVFLH
PGGFYSGSGR SNLFAGPQNL MDRDIVLVTL NYRLGSLGFL ATGTADATGN MGLKDQVVAL
RWIQKHIGKF GGDCSSVTLW GYSAGSFSTG LHMMSPMSKG LFQRAIMMSS APLGQIDFKD
NQLELAQKQA QLLKCPEKPI KEMVACLKTK PTTDFVNTVR EMFEYAGKPI YNWMPVVEPD
FGQERFIAED PYKIMEKGAI NKVPLIIGIT QYEFQYVAYY ILRNDTEREL FNKDFEKLAP
IHLLYERNTE KSRLISRKLK EKYLNNQSLV FPDSVEKFGQ LYSDGVIGYS YHRFLDMVSK
HTPVFSYLFT YKGRYSHFIN PSTNQSEGAM HHDELLYHFY VPVRTPLFSE TDPENKIIER
LTRMWTEFAK RGNPNDSKDG YLKDFEWPMY TDGKKEYLEI GENLTKIKGG IFVDRFQLWD
SLFPLN
//
