GenomeNet

Database: UniProt
Entry: A0A1B0G1T7_GLOMM
LinkDB: A0A1B0G1T7_GLOMM
Original site: A0A1B0G1T7_GLOMM 
ID   A0A1B0G1T7_GLOMM        Unreviewed;      5092 AA.
AC   A0A1B0G1T7;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   28-FEB-2018, entry version 11.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:GMOY007253-PA};
OS   Glossina morsitans morsitans (Savannah tsetse fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Hippoboscoidea; Glossinidae; Glossina.
OX   NCBI_TaxID=37546 {ECO:0000313|Proteomes:UP000092444, ECO:0000313|VectorBase:GMOY007253-PA};
RN   [1] {ECO:0000313|Proteomes:UP000092444, ECO:0000313|VectorBase:GMOY007253-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Yale {ECO:0000313|Proteomes:UP000092444,
RC   ECO:0000313|VectorBase:GMOY007253-PA};
RA   Lawson D.;
RT   "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of
RT   African Trypanosomiasis.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:GMOY007253-PA}
RP   IDENTIFICATION.
RC   STRAIN=Yale {ECO:0000313|VectorBase:GMOY007253-PA};
RG   VectorBase;
RL   Submitted (JUL-2016) to UniProtKB.
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DR   EMBL; CCAG010006899; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   VectorBase; GMOY007253-RA; GMOY007253-PA; GMOY007253.
DR   Proteomes; UP000092444; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 3.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 4.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000092444};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000092444};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4419   4439       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4610   4631       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4695   4717       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4884   4906       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4960   4983       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       21     75       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN       82    127       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      137    198       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      204    262       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      270    328       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      511    737       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN      966   1151       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1410   1632       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   COILED      394    414       {ECO:0000256|SAM:Coils}.
FT   COILED     3748   3768       {ECO:0000256|SAM:Coils}.
FT   COILED     4552   4583       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   5092 AA;  576402 MW;  F6FA34AF9D3BF509 CRC64;
     MTCVLTTRQD SQFGKGTGSG HRTLLYGNAI LLRHHNSDMY LACLSTSSSN DKLSFDVGLQ
     EHSQGEACWW TVHPASKQRS EGEKVRVGDD LILVSVATER YLHTTKENEL SIVNASFHVT
     HWSVQPYGTG ISRMKYVGYV FGGDVLRFFH GGDECLTIPS TWGREAGQNN CSFLLSIVVY
     EGGSVMSQAR SLWRLELART KWTGGFIMWF HPMRFRHITT GRYLGVNDNN ELILVKKEEA
     SIATTTFCLR LEKDDEKKVL EDKDLEVIGS PIIKYGDTTV IVQHCESGLW LSYKSYETKK
     KGVGKVEEKQ AILHEEGKMD DCLDFSRSQE EESKTARVIR KCSSLFTQFI SALETLQLNR
     RHSVFFQKVN LNEMVMCLED LINYFSQPED DMEHEEKQNR FRALRNRQDL FQEEGVLNLI
     LEAIDKINSI TSQGFLASFL AGDETGQSWD LISTYLYQLL AAIIKGNHTN CAQFANSNRL
     NWLFSRLGSQ ASSEGSGMLD VLHCVLIDSP EALNMMRDEH IKVIISLLEK HGRDPKVLDV
     LCSLCVGNGV AVRSSQNNIC DFLLPGKNLL LQTQLVDHVA SIRPNIFVGR VEGSALYQKW
     YFEITMDHIE QTTHMMPHLR IGWANTTGYV PYPGGGKKWG GNGVGDDLYS FGFDGAYLWT
     GGRKTLVMDQ VPEEPFIRKC DVIGVTIDLS VPVITFTFNG NKVRGCFREF NLDGMFFPVM
     SCSSKLSCRF LFGGDHGRLK FAPPLGFSPL VQCLMPHQIL SLDPCFYFGN LYKNVLAGPW
     LIEDDTAFVP QPVDTSGVSL PSSVDQIKEK LAENIHEMWA LNKIEAGWTW GEHRDDYHRI
     HPCLTQFEKL PPAEKRYDNQ LAVQTLKTVV ALGYYITMDK PPARIRPIRL PNELFMQANG
     YKPAPLDLSA VTLTPKLEEL VDQLAENTHN LWARERIQQG WTYGLNEDSE NLRSPHLVPY
     AKVDEAIKKA NRDTASETVR TLLVYGYVLD PPTGEGNEAL LAEALRLKFA AFRTYRVERN
     YAVTSGKWYF EFEVLTSGPM RVGWARADCN PGSMLGSEDT SWAFDGHNVT KVHAGAVEHF
     GILYEAGDVI GCFIDVKEQN IKKVFGGASE TFGKQCGPGD IVGVFLDVAD HTISFSLNGE
     LLMDALGGET TFADVTAEGV GFVPACTLGV GQKARLIYGQ DVDSLKFFTT CGLQEGYEPF
     CVNMRRPVTH WYTKDQPIFE NTEEMPDCRI DVTRIPGGAD TPPHLKISHN TFETMEKANW
     EFLRLSLPVT CMGEFISEAE KARRWEEIKL RQYRLMRDAE IAQQQTSAHM DHMLKSGFTM
     SDIKGLNRNY DDTAEADENM RGPSRPPRKG SITRNITFEQ DGLALPEELQ GSTLDINGLD
     GEALDEKKKR GRSPFKFFSK KSRDQSKEKT AGRAPEVSVE RRNTVAHGRN VVNAQMAARA
     PTLRLNNVEM PQTPTPTGPK PLSGGTLGQP PIESSGNEMF DAECLKLINE YFYGIRIYPG
     QDPTHVYVGW VTTQYHLHSK EFNKNRVRRG SVIIEDEYEN PIERIDRQSC YVVRADELFN
     EVTQDASGKG ASQGMFVGCF VDTATGTIRF TCEGKDTSHR WLMEPNTKLF PAIFVEATSK
     EILQIELGRT ATTLPLSAAV LPTSDKHINP QSPPRLKVQC LRPHQWARVP NTALQVHALK
     LSDIRGWSML CEDPVSMLAL HIPEEDRCID ILELIEMDKL LSFHAHTLTL YAALCYQSNY
     RAAHALCQHV DQKQLLYAIR SEYMSGPLRQ GFYDLLIALH LESHATTMEV CKNEFIIPIG
     PELKVLYEDE EMCHSLRSLV TESVRPQMRM TDITETVPEI DQLYSPKFPL EIVREFVMEA
     LQEAVEVNQV HNRDPIGWTN ENLFLPLIKL TDRLLLVGVL TDEDVQKLLL MVDPETWDVN
     FEKGKPHGKD EHRKGLLTMK MAEGAKLQMC YLLQHLYDIQ LRHRVESIIA FSHDFVGDLQ
     GDQLRRYIEI KQSDLPSAVA AKKTKEFRCP PREQMNQILC FKNLEPDDQE NCTCGLDLRG
     RLHDFHDGLM KKVSLNALQE PDEPESNGVE EVKTGPITKI FNFINTVKEL EEGPKEVEEP
     EKKTPEEVFR KVLIKTIVSW AEESQIENPK LVREMFSLLV RQYDTVGELV RALGKTYVIN
     NKARNDAAEM WVGLSQIRAL LPVQMSQDEE ELMRKRLWKL VNNATFFQHP DLIRILRIHE
     NVMAVMMNTL GRRAQAQSDA PAQTEGMEGA PHKEKDTSHE MVVACCRFLC YFCRTGRQNQ
     KAMFDHFDFL LDNANILLAR PSLRGSTPLD VAYSSLMENT ELALALREHY LEKIAIYLSR
     CGLQSNSELT EKGYPDLGWD PVEGERYLDF LRYCVWVNGE SVEENANLVI RLLIRRPECL
     GPALRGEGEG LFRAIVEANR MSERISERCK IQDEPEGTIT GLNFTHPLPE GDEDEDYIDT
     GAAILNFYCT LVDLLGRCAP DASVIEQGKN ESLRARAILR SLVPLEDLQG VLSLKFTILQ
     TAPGEERPKS DMPSGLLPNN KQSIVLFLER VYGIETQDLF YRLLEDAFLP DLRTATILDK
     SDGSESDMAL AMNRYIGNSI LPLLIKHSKF YNEAENYASL LDATLHTVYR LSKNRMLTKG
     QREAVSDFLV ALTSQMQPAM LLKLLRKLTV DVSKLSEYTT VALRLLTLHF DRCAKYYGSS
     QGQGSYGAAS DEEKRLTMLL FSNIFDSLSN MDYDPELFGK ALPCLIAIGC ALPPDYSLSK
     NTEEDYYGRQ SGSPDQPQYD PNPIDTTNVH LTNDYNSLVQ KFSEHYHDAW ASRRLESGWT
     HGEIRSDTDR KHPRLKPYNM LSEYERERYK DPVRECLKAL LAIGWTIEHS DIDVPQNNRG
     SVRRQSKPQI HDFQSEGSAF NYHPHPVDMT NLTLSREMQN MAERLAENSH DIWAKKKKEE
     LDTCGGAIHP QLVPYDLLTD KEKRKDRERS QEFLKYMQYQ GYKLHKPSKG GAEGEGGAAM
     IAVESRFSYS LLEKLIQYLD RATINMKLLK PSTTFSRRSS FKTASRDIKF FSKVVLPLME
     KYFSTHRNYF IAVATATNNV GASLKEKEMV ASIFCKLASL LRNRLTAFGP DVRITVRCLQ
     VLVKGIDART LVKNCPEFIR TSMLTFFNQT ADDLGTTILN LQDGKYSHLR GTHLKTSTSL
     GYINQVVLPV LTAMFDHLAG CDYGSDLLLD EIQVASYKIL AALYHLGTDG TLTHERKYLK
     TEIDRHRPAL GSCLGAYSSC FPVAFFEPHL NKHNQFSLLN RIADHSLEAQ DIMVKMESCM
     PNLEAVLNEV DQFVESDKTY VDAPHIIDVI LPLLCSYLPF WWAQGPDNVS PTSGNHVTMV
     TADHMNSLLR NVLKMIKKNI GNDNALWMTR IAAYTQQIII NTSEELLKDP FLPLAERVKK
     RTENMYHKEE SMRGFIKSAS DDTSQVETQL QEDWNLLVRD IYSFYPLLIK YVDLQRNHWL
     KDNIPEAEEL YNHVAEIFNI WSKSQYFLKE EQNFISANEI DNMALIMPTA ARRSGITEGA
     PVTGGKAKKK KKNRDKKRDK DKEIQASLMV ACLKRLLPVG LNLFAGREQE LVQHCKDRYL
     KKMQEYDVID FARNQLTLPD KLDPSDEMSW QHYLYSKLGK KEEPPTEEQA VEKSTNQNEK
     GKDKTEETVD RIVAMAKVLY GLHMSSRHKL KSKSRVSKIT MARRRAVLSS LRSIHLYRVS
     RHRACNIFAR TYYEQWLEEE NVGQEVMIED LTQSFEESEK SKKDEEETEG KPDPLTQLVT
     TFCRGAMTER SGALQEDLLY MSYAQIAAKS CGEEEEEGGG EEEGEEAEGG GGGSEGESSK
     IHEQEMEKQK LLFHQARLSN RGVAEMVLLH ISASKGIPSE MVMTTLNLGI AILRGGNIDI
     QMGMLNHLKE KKDVGFFTSI AGLMNSCSVL DLDAFERNTK AEEYIPSAGA GLGVGSEGAA
     GEKNMHDAEF TCALFRFIQL TCEGHNLDWQ NYLRTQAGNT TTVNVVICTV DYLLRLQESI
     MDFYWHYSSK EIIDPAGKAN FFKAIGVASQ VFNTLTEVIQ GPCSLNQQAL AHSRLWDAVG
     GFLFLFSHMQ EKLSKHSSQV DLLKELLNLQ KDMITMMLSM LEGNIVNGTI GKQMVDTLVE
     SAGNVELILK YFDMFLKLKD LIESASFQEI DMKNEGWVTP KDFRDKMEQS KNYTPEEMDF
     LLACCERNHE GKIDYAAFVD RFHEPSTEIG FNLAVLLTNL SEHMPNEPRL ARFLETAGSV
     LNYFEPFLGR IEILGSSKRI ERVYFEIKDS NIEQWEKPQI KESKHAFFYS IVTEGGDKEK
     LEAFINFCED AIFEMTHASG LMATDDGGGN VKRDPSYSSY MSEEEEERAA RDPIRRTINA
     VKDGLKFGLY MLSPANIKHQ IGVMQTKSVP ELIIGFFKII FYIFYYMGYA NFAVVRYIFG
     ILMNLMRGPA PEEVEAPPVE EETFGKALPP LPTEEPPGTV QAFGLDINKE ENGQYKVTVH
     ESSASGTASS GEETAESSPE DAAASAEGQA VEGEAHHAEP VSIVDLLGGE AAKKAAQERQ
     EAQKAQEAAM ASIEAEAKKA STETQETPAV HQIDFSQYGR RAVSFLARNF YNLKLVALVL
     AFSINFMLLF YKVTSFAEDE EASGEDELIL GSGSGAGLAG SGLGSGEGSG EGGEDEEDIP
     ELVHVNEDYF FMEHVIRVAA ILHSLISLCM LIAYYHLKVP LAIFKREKEI ARRLEFDGLF
     IAEQPEDGDV KSHWDKLVIS AKSFPDSYWD KFVKKKVRQK YSETYDFDSI SNLLGMEKSA
     FVAQEAESGG LIKYFMNIDW RYQIWKAGVT FTDNAFLYSL WYFSFSVMGN FNNFFFAAHL
     LDVAVSYKTL RTILQSVTHN GKQLVLTVML LTIVVYIYTV IAFNYFRKFY IQEEDDEVDK
     KCHDMFTCFV FHLYKGVRAG GGIGDEIGDP DGDDYEVYRI IFDITFFFFV IVILLAIIQG
     LIIDAFGELR DQLQSVQDNM ESNCFICGMS KDFFDIVPHG FDTHVQKEHN LANYMFFLMH
     LINKPDTEYT GQETYVWNMY QQRSWDFFPV GDCFRKQYED ELSGGGGGGG GG
//
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