ID A0A1B0G2G5_GLOMM Unreviewed; 2221 AA.
AC A0A1B0G2G5;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=MI domain-containing protein {ECO:0000259|PROSITE:PS51366};
OS Glossina morsitans morsitans (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=37546 {ECO:0000313|EnsemblMetazoa:GMOY007500-PA, ECO:0000313|Proteomes:UP000092444};
RN [1] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RG International Glossina Genome Initiative W.H.O.;
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:GMOY007500-PA}
RP IDENTIFICATION.
RC STRAIN=Yale {ECO:0000313|EnsemblMetazoa:GMOY007500-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
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DR EMBL; CCAG010010409; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 37546.A0A1B0G2G5; -.
DR EnsemblMetazoa; GMOY007500-RA; GMOY007500-PA; GMOY007500.
DR PhylomeDB; A0A1B0G2G5; -.
DR Proteomes; UP000092444; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.180; -; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF9; EUKARYOTIC TRANSLATION INITIATION FACTOR 4G1, ISOFORM B-RELATED; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS51366; MI; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 1798..1928
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT REGION 1..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 156..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 465..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..648
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 767..938
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1081..1100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1543..1671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1702..1795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2070..2091
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2172..2194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 981..1011
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 20..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 465..480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..624
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 767..831
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..919
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1544..1567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1597..1671
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1702..1757
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2070..2090
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2221 AA; 243927 MW; 355E5C38C931DDB4 CRC64;
MKRSLKDPSM FVHTGGGGKG IRPSQQQQQQ QQQQQQQQQH HHQSHHHTAH QQQPQQQQQL
QLQAGSVHLS HPTTANQSST HSHPHPQQQQ QQQQQQQQQT QQLQHHLQHH PQLPLAYFPY
QVHQVQAAPP PNAQHQLQGN ASNVAAAAAH LASTLSSQGA NNGMGSGGNG SQGPHSNNTS
GSNNSNAANI TTRQANTNSN MPHFAPGSTL IQTSMPPPNT SHAAFMTPAF MQLQQQSTAV
MVAAAQYSTV AAAAAAAAGN HGNPGTGQGA TALFPTPQQS QQTNNQHHQT AALHHAQQTL
HYFHTNAGAT ALTPTQSHLH HQQHQMRSII PAAVHQRQHA PGTISIFPPN YFALQATALA
PAPRTSLLTN VHQQTAAASA SAVHVAHQLP NATGRGAPAG PTTYVSPPYC TPPLQLGTAA
GLPPQSSSIL ATAASMAAPG LQGPFGHLTG AISASTSSTS LNIASGAGGN TSSSNAAGGE
HLATKQRRHA IPIVHPVTLK PLKFPEPHEK NTAVEVRSPI SVTSDTGEIS HGQKTTQTKD
SDQATNDITE VSPNATLIMT KVPSQGSKDK IDQQMQTDAV KDKSGSISST TETTANVQDL
MEEGLTSSKP QSEEISQTSV CGGGEQDDTD ADTTELEDYP ASTTQASEEN VIKQKEIMNA
MALNYEQLVT SSDELIESRV EDHSCNKSDD VKQSVVNVPV KDDVIIAAVE IDAGDRKQSK
KKICNAVDEI QEDIAELKSQ QNSASPTMMS STEDKIAIET ITTVTTTTTT TTNNNNKHPN
DSLKTAINSS NPNTQVRSEE KSSSHSNAAA TTTNNKQKTG GNTSSALATS RNKEEKTQKA
ANKSNAVNPV ASNNSNTNRS NKHHATGGNK LIDTTTTISG NNNNNNNDNN SGFSSKDLAA
SATLLSSSSK HQTQQRAAAN ARAAGGGIGG SGGQSKETDI KTDIENSNQQ RKHTKTQEIL
AQFLQPSILS EGNSGSELNS IKQEEQQLQF LNSSSSACED EEERLQLLKQ QQQQPQFQQD
QDYTDIRFGD FKEYEKLIDT RQTTSPGVTM IVGGKSHQKH KTSATNNDTV DSTVGMKNYP
LTHHRSSKSQ NAHGHHSHSA VTVALDSQKP AIIKYNLEEL KAFAKAPVAR KPPVLELHKN
NGGNDCIMQL FVSRQQHHHL SHHGGHNMPS MGLQQQQQQY QHMNFNESLE FVGGKRRQGR
KHDHQMVRVN ATVISNANAG AGGVSAAAVA AAAGGGNLSL QYPREKEIIR VHLSLNEEIK
LSECENAWQP ETLRSKSNNS VALAVNPTNE DIDSVLKRVR GVLNKLTPDN FEVLLKTMTN
ISMNTQEKMQ QVMLLIFEKT VSEPNFAPTY AKFCKMLFQE IKHDSKTLFN SSLIKRIQHE
FETNVNDADA KKVKLQPLVD KMDASNDAKE KLELQAEIED QEYQFRRRAW GTVRFIGEMY
KLQSLTSDRV LLCIESLLEH GSEEKLEYMC KLLTTVGHLL EGSGSDHCNS NARMDKIFIR
MHDIVNKSRA NVKAATASIN QTKISSRVRF MMQDVIDLRS RNWDQPASHG NQGGSGGSNS
SQQQQQQQHR RRQDDKFSHG SGNANYERGS RGGGLGYGGG NNSSNQRQSR LMSTDMRDSS
VGGAAGSSGS GGNYFMQKQQ KSQFMTQQEQ SIDPKKLNFS RGDDTNQTNT KLGNSSIYIW
RAHGRQGTNA LAGTSIAIST ATSTGSHTMS QHQQSQQQHQ QHSYGASSSS TSSNNSSNNN
SFKRQTNQYQ NQSSSSPVAK EREEKLSNYQ TSSSGGIGTG SEDDEKCDSS QQTFSEKDNQ
KLLNRLLEEV MGCSSIHNKA WQQEVLKTWR STSRRQQVSL LHYLLIDYLH LSQVKKAQRS
ACAAVFSHLL RTKAFDKKVF GQAYEQFADE FPDLLVDVPN GWCYAFEFLG PMLHERLISF
NDIWQQQWRD DRHFTERFLK ALVIHFTREF GANYLRDLWH KEFKLDRGQL FFNDQQQWRE
FVKNNTLDFI YDCGHNPAPE MTALGTKAIN SNALVEQHIK RIECLLNDCN DCDLAIDYIN
TNVNINSQFI KTLTRFLCCD YATVMTSAIP SSNSSTSSNN SNSRRPNSDA GPQLNVELFR
YKCIPLLRRC VDAQETFELC CLDAIIESLK EYYDAQTADD MICNVLDLLY HDCEIISRDT
FEKWYKTRRQ LSPGDNSTTM MNSDQQQKSQ FVGQGAGSNA VNRENLTPLS AHLHAYIQKL
L
//
