ID A0A1B0G3C4_GLOMM Unreviewed; 563 AA.
AC A0A1B0G3C4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Ionotropic glutamate receptor C-terminal domain-containing protein {ECO:0000259|Pfam:PF00060};
OS Glossina morsitans morsitans (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=37546 {ECO:0000313|EnsemblMetazoa:GMOY007825-PA, ECO:0000313|Proteomes:UP000092444};
RN [1] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RG International Glossina Genome Initiative W.H.O.;
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:GMOY007825-PA}
RP IDENTIFICATION.
RC STRAIN=Yale {ECO:0000313|EnsemblMetazoa:GMOY007825-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
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DR EMBL; CCAG010013760; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0G3C4; -.
DR STRING; 37546.A0A1B0G3C4; -.
DR EnsemblMetazoa; GMOY007825-RA; GMOY007825-PA; GMOY007825.
DR VEuPathDB; VectorBase:GMOY007825; -.
DR PhylomeDB; A0A1B0G3C4; -.
DR Proteomes; UP000092444; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050907; P:detection of chemical stimulus involved in sensory perception; IEA:UniProt.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR PANTHER; PTHR42643; IONOTROPIC RECEPTOR 20A-RELATED; 1.
DR PANTHER; PTHR42643:SF37; IONOTROPIC RECEPTOR 84A; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 299..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 297..531
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00060"
SQ SEQUENCE 563 AA; 64661 MW; E47C23BFDF6B2A37 CRC64;
MAQGFPVHVW SGRDYLQDTP AAPIHRPSNS FRTDNDTRRP LKFQMKALSF KIGVFLANFN
SECGLNVLRW SAASEHNYFT TNRFWLLVTQ DTADVAALED PHIFIPPDSE VRIVVVLPLK
SFILSDIFKV ASFKASKQLT ISRNFSHSWQ MIGDLQKFGS AISYRENLEN ITFNTGLVIA
FPDMFTNIED LSLRHIDTIS KVNNRLTLEL GNKLNMHFNT HQMDNYGWRQ PNGSFDGLMG
RFQRHELDFG QMAIFMRLDR IALCDFIAET YRIRAGIMFR QPSLSAVANI FAMPFENDVW
IALVILIVFT ILIFILELLF SPYKHNMDYW DCAVFVWGAM CQQGFYLNVT NRSCRIVIFT
TFVANLFLFT SFSANIVALL QSPSEAIKSL RDLTQSPLEV GVQDTVYNKV YFNESTDPVT
NLLYHKKIAS KGENIYIRPM VGMEKVRTGL FAYQVELQAG YQIISDTFNE PEKCGLKELE
AFQLPIIAIP TRKNFPYKEL FRRQLRWQRE TGLMNREERK WFPQKPKCEG GVVGFISVGI
TECRYALVMF TMGAGTSNAA VHF
//
