ID A0A1B0G6M7_GLOMM Unreviewed; 477 AA.
AC A0A1B0G6M7;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
OS Glossina morsitans morsitans (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=37546 {ECO:0000313|EnsemblMetazoa:GMOY008971-PA, ECO:0000313|Proteomes:UP000092444};
RN [1] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RG International Glossina Genome Initiative W.H.O.;
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:GMOY008971-PA}
RP IDENTIFICATION.
RC STRAIN=Yale {ECO:0000313|EnsemblMetazoa:GMOY008971-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR EMBL; CCAG010009609; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0G6M7; -.
DR STRING; 37546.A0A1B0G6M7; -.
DR EnsemblMetazoa; GMOY008971-RA; GMOY008971-PA; GMOY008971.
DR VEuPathDB; VectorBase:GMOY008971; -.
DR PhylomeDB; A0A1B0G6M7; -.
DR Proteomes; UP000092444; Unassembled WGS sequence.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR43142; CARBOXYLIC ESTER HYDROLASE; 1.
DR PANTHER; PTHR43142:SF1; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Serine esterase {ECO:0000256|ARBA:ARBA00022487}.
FT DOMAIN 88..314
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT DOMAIN 324..449
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 477 AA; 54432 MW; 015834D159F4980E CRC64;
MVDFKVQQRR YRTNEKIIVS TTYGPIKGVK RKTIYGDSYY SFEGIPFAKP PLGDLRYKAP
LPPDSWTDVR SCTSVGPKPL QKHFVFQMTE ATRDLYSPDY LLREEVVVVS ITYRVGPFGF
LSLQDCDIEV PGNAGLKDQV MALRWIKANC SRFGGDSENI TLFGDSAGAA SVHYMMLTEQ
TRNLFHKAIC MSGCALSPWA VTPQRNWPYR LAKAAGYTGD DNELAVFEFL SQAKGADIVK
ANEDLCTDEE KRERIGFSFG PVIEPYLTQH CVVPKAPTEM MRTAWGNTIP MIIGGVSNEG
LLLYTETKNN PKLLNELGDC RYVMVSHEYF WFPIYRTVLS RLEYASSAPT YLYRFDFDSK
HFNHLRIISC GKKVRGTCHG DDLSYIFYNS VARKLKKHTK EYKCIERLVG MWTQFAASSN
PNYEKDQNEL WLPVTMASLE KNQLKCLNIA DDLKIIEVPD MDKLLVWEGF YTSNQLL
//
