ID A0A1B0GCF8_GLOMM Unreviewed; 1134 AA.
AC A0A1B0GCF8;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=MI domain-containing protein {ECO:0000259|PROSITE:PS51366};
OS Glossina morsitans morsitans (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=37546 {ECO:0000313|EnsemblMetazoa:GMOY010984-PA, ECO:0000313|Proteomes:UP000092444};
RN [1] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RG International Glossina Genome Initiative W.H.O.;
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:GMOY010984-PA}
RP IDENTIFICATION.
RC STRAIN=Yale {ECO:0000313|EnsemblMetazoa:GMOY010984-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}.
CC -!- SIMILARITY: Belongs to the CWC22 family.
CC {ECO:0000256|ARBA:ARBA00006856}.
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DR EMBL; CCAG010021399; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0GCF8; -.
DR STRING; 37546.A0A1B0GCF8; -.
DR EnsemblMetazoa; GMOY010984-RA; GMOY010984-PA; GMOY010984.
DR VEuPathDB; VectorBase:GMOY010984; -.
DR Proteomes; UP000092444; Unassembled WGS sequence.
DR GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR Gene3D; 1.25.40.180; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR18034; CELL CYCLE CONTROL PROTEIN CWF22-RELATED; 1.
DR PANTHER; PTHR18034:SF3; PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG; 1.
DR Pfam; PF02847; MA3; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51366; MI; 1.
PE 3: Inferred from homology;
FT DOMAIN 641..757
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT REGION 1..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 594..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 857..1134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..55
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..93
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..140
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..198
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..274
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..305
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..613
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 857..905
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 910..949
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 956..979
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 980..1134
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1134 AA; 129397 MW; E769A7543964D36D CRC64;
MGESDSENTN SSSSNDSSSS SSSNSRESVK SVKMKEAEPQ KDGKSAAKFK SRWDQRNEFT
QSQPAVKKDD CELDKTNNEK NSESTKLISM NEKHARGEYS ANATRTPLND SESKVNPREG
DAKIQNEDEA KTKEVCEEQH NNAKAINVNK LNSSSINANK EVENSEKTKS ADEPVGKLIP
RSRSRSSDRN EATARKRDNH SRHSRSPKTK RDRSKSNSFE RRSKKQRERE RSHSEESKLR
RSKRSESLER RREERRKRHA EREDRGRPNK RSVSKERQIT SNAAAAVGDK SKDDGADKMT
ERQRRTVDLL TSRTGGAYIP PAKLRLMQAE ITDKSSIAYQ RLAWEALKKS IHGYINKVNV
DNIAIITREL LKENIVRGRG LLCRSIIQAQ AASPTFTHVY AALVAIINSK FPKIGELLLK
RLVIQFKRAF RRNDKNVCLS STRFIAHIVN QRVAHEILAL EILTLLVEMP TDDSVEVAIA
FLKECGMKLT EVSSKGTGAI FEMLKNILHE GKLDKRVQYM IEVVFQVRKD GFKDHQSVIE
SLELVEENDQ FTHLLTLDEA TDPEESLNAF KFDENFETNE DKYKGLSREI LGSDASASDG
SSSSAGSASE SDGASDSDDG EADKTATSGD IIDNTETNLI ALRRTIYLTI NSSLDYEECA
HKLMKMQLKP GQEIELCHMF LDCCAEQRTY EKFYGLLAQR FCAINKIYIE PFEEIFKDTY
QTTHRLDTNR LRNVSKFFAH LLFTDAIGWD VLECIKLNED DTTSSSRIFI KILFQELAEY
MGLSQLNRKL KDEALIESLA GVFPKDNPRN TRFSINFFTS IGLGGLTDEL RQFLKNAPKS
VPAINAEILA NKPVKVTTES SSSTSASSSS TTSSSSSSGS SSSSSSSDSS NSSSSESSTD
SNSDSILKKI KGKRKIKSNK KQRKNSNIKN KKHKTKKSKK KKIKKTKKHR QESSSSSSES
ESISDSMSSS SNSSRSGESN SKVKTRKTTE AKTSAKPVER SNEKDKHQKD IKRHRQQDEN
GYDEKVDENR VEQRERELVR RREERERRHR ERDQQEECKK VRERSELERS PGDRERRHNR
DRHRDPDRYE ERRRQDERER TRSRSRDHRK RETYAKKQHE YERSRIRTTS KERG
//
