ID A0A1B0GE47_GLOMM Unreviewed; 733 AA.
AC A0A1B0GE47;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 03-MAY-2023, entry version 29.
DE RecName: Full=TFIIS N-terminal domain-containing protein {ECO:0000259|PROSITE:PS51319};
OS Glossina morsitans morsitans (Savannah tsetse fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Hippoboscoidea;
OC Glossinidae; Glossina.
OX NCBI_TaxID=37546 {ECO:0000313|EnsemblMetazoa:GMOY011571-PA, ECO:0000313|Proteomes:UP000092444};
RN [1] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yale {ECO:0000313|Proteomes:UP000092444};
RG International Glossina Genome Initiative W.H.O.;
RA Lawson D.;
RT "Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African
RT Trypanosomiasis.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:GMOY011571-PA}
RP IDENTIFICATION.
RC STRAIN=Yale {ECO:0000313|EnsemblMetazoa:GMOY011571-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00649}.
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DR EMBL; CCAG010012093; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0GE47; -.
DR STRING; 37546.A0A1B0GE47; -.
DR EnsemblMetazoa; GMOY011571-RA; GMOY011571-PA; GMOY011571.
DR VEuPathDB; VectorBase:GMOY011571; -.
DR PhylomeDB; A0A1B0GE47; -.
DR Proteomes; UP000092444; Unassembled WGS sequence.
DR GO; GO:0070449; C:elongin complex; IEA:InterPro.
DR GO; GO:0006368; P:transcription elongation by RNA polymerase II; IEA:InterPro.
DR CDD; cd00183; TFIIS_I; 1.
DR Gene3D; 6.10.250.3180; -; 1.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR010684; RNA_pol_II_trans_fac_SIII_A.
DR InterPro; IPR003617; TFIIS/CRSP70_N_sub.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR15141; TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3; 1.
DR PANTHER; PTHR15141:SF76; TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3; 1.
DR Pfam; PF06881; Elongin_A; 1.
DR Pfam; PF08711; Med26; 1.
DR SMART; SM00509; TFS2N; 1.
DR SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00649}.
FT DOMAIN 9..82
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT REGION 83..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..159
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..244
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..298
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..333
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..356
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..414
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 733 AA; 82093 MW; 38B26E39D9973C1C CRC64;
MSSTTSIVEV IQHYQRSIGS SQDDEARLLH CINKLYKLPI KVEHLQETGV GKTVNSLRKY
NGEIGVAAKT LVTKWKAMVA AEEEPADAAT STSSAHRENG RDSGENDDEE SYHRNNSSPK
EEKKDKEQHN EQNYKDISSH SKDICTKPSS LLENSSDKNV KNSNEQHRKS SSSSSLVNDK
GKDKERYHKS RSSNGGKDRG RDKDKRDHKD KHKERDEEKD RKDIKHKPET TTSITPGSNS
SSSSSKKKID EKYKHHSQQH RENREKTDNH KHRAESKQKS SSRDKERRKG KSSNSAKEDE
SPEGNCAATS NKNESSERKR RRNSDDDSND FLSPRPKVVK MKTSSKKDSK TETENENDEE
GGFDSSTGAN FADVLGMLNA PTKKVKKPVK SSSSPASSTS KLSSSSSPYN SSSKTSALKT
VTTYSYTSTP SVSTPVSTKP DLLAPTAKLE PLDPSIALEL PTISTNYKPM PLNQTVMDCV
FNTNMSSSSK PIRTLTDAEA LNHGISSKTI RTKIYSGAKT GQILQVPSLF DLCIRILQKN
IDALEYTGGV PFEVLRPVLE RATPHQLLVF EDYNPYLMED SDVLWQLHVQ RNYRSQKRLE
NESWREMYLR CQEDQERKLN YLADSIKQSQ KIAAAPVRKT QLAFVDSMVK PPRNIQRKQE
QFGTQAKLVA TPAARVASLS SVTPNAAKTD DVRLKVASSI RDHAQVSSAA AVRPKKAPLM
QKTLQFIRGR HKR
//
