ID A0A1B0GHJ4_LUTLO Unreviewed; 2640 AA.
AC A0A1B0GHJ4;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Putative apolipophorin corethrella appendiculata {ECO:0000313|EMBL:MBC1169452.1};
OS Lutzomyia longipalpis (Sand fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC Lutzomyia; Lutzomyia.
OX NCBI_TaxID=7200 {ECO:0000313|EnsemblMetazoa:LLOJ001503-PA, ECO:0000313|Proteomes:UP000092461};
RN [1] {ECO:0000313|Proteomes:UP000092461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Jacobina {ECO:0000313|Proteomes:UP000092461};
RA Richards S., Qu C., Dillon R., Worley K., Scherer S., Batterton M.,
RA Taylor A., Hawes A., Hernandez B., Kovar C., Mandapat C., Pham C., Qu C.,
RA Jing C., Bess C., Bandaranaike D., Ngo D., Ongeri F., Arias F., Lara F.,
RA Weissenberger G., Kamau G., Han H., Shen H., Dinh H., Khalil I., Jones J.,
RA Shafer J., Jayaseelan J., Quiroz J., Blankenburg K., Nguyen L., Jackson L.,
RA Francisco L., Tang L.-Y., Pu L.-L., Perales L., Lorensuhewa L.,
RA Munidasa M., Coyle M., Taylor M., Puazo M., Firestine M., Scheel M.,
RA Javaid M., Wang M., Li M., Tabassum N., Saada N., Osuji N., Aqrawi P.,
RA Fu Q., Thornton R., Raj R., Goodspeed R., Mata R., Najjar R., Gubbala S.,
RA Lee S., Denson S., Patil S., Macmil S., Qi S., Matskevitch T.,
RA Palculict T., Mathew T., Vee V., Velamala V., Korchina V., Cai W., Liu W.,
RA Dai W., Zou X., Zhu Y., Zhang Y., Wu Y.-Q., Xin Y., Nazarath L., Kovar C.,
RA Han Y., Muzny D., Gibbs R.;
RT "Whole Genome Assembly of Lutzomyia longipalpis.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:MBC1169452.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Jacobina {ECO:0000313|EMBL:MBC1169452.1};
RC TISSUE=Midgut {ECO:0000313|EMBL:MBC1169452.1};
RA Coutinho-Abreu I.V., Serafim T.D., Meneses C., Kamhawi S., Oliveira F.,
RA Valenzuela J.G.;
RT "Leishmania infection induces a limited differential gene expression in the
RT sand fly midgut.";
RL BMC 21:608-608(2020).
RN [3] {ECO:0000313|EnsemblMetazoa:LLOJ001503-PA}
RP IDENTIFICATION.
RC STRAIN=Jacobina {ECO:0000313|EnsemblMetazoa:LLOJ001503-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00557}.
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DR EMBL; AJWK01005229; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GITU01000749; MBC1169452.1; -; Transcribed_RNA.
DR EnsemblMetazoa; LLOJ001503-RA; LLOJ001503-PA; LLOJ001503.
DR VEuPathDB; VectorBase:LLOJ001503; -.
DR OrthoDB; 3138458at2759; -.
DR Proteomes; UP000092461; Unassembled WGS sequence.
DR GO; GO:0005319; F:lipid transporter activity; IEA:InterPro.
DR Gene3D; 2.20.80.10; Lipovitellin-phosvitin complex, chain A, domain 4; 1.
DR Gene3D; 2.20.50.20; Lipovitellin. Chain A, domain 3; 1.
DR Gene3D; 1.25.10.20; Vitellinogen, superhelical; 1.
DR InterPro; IPR015819; Lipid_transp_b-sht_shell.
DR InterPro; IPR011030; Lipovitellin_superhlx_dom.
DR InterPro; IPR015816; Vitellinogen_b-sht_N.
DR InterPro; IPR015255; Vitellinogen_open_b-sht.
DR InterPro; IPR015817; Vitellinogen_open_b-sht_sub1.
DR InterPro; IPR001747; Vitellogenin_N.
DR PANTHER; PTHR23345:SF15; VITELLOGENIN-1-RELATED; 1.
DR PANTHER; PTHR23345; VITELLOGENIN-RELATED; 1.
DR Pfam; PF09172; Vit_open_b-sht; 1.
DR Pfam; PF01347; Vitellogenin_N; 1.
DR SMART; SM01169; DUF1943; 1.
DR SMART; SM00638; LPD_N; 1.
DR SUPFAM; SSF48431; Lipovitellin-phosvitin complex, superhelical domain; 1.
DR PROSITE; PS51211; VITELLOGENIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00557};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..2640
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5033265688"
FT DOMAIN 41..646
FT /note="Vitellogenin"
FT /evidence="ECO:0000259|PROSITE:PS51211"
FT DISULFID 434..439
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00557"
SQ SEQUENCE 2640 AA; 288795 MW; BDEFAA4D549E9746 CRC64;
MARFLAISIV TVALLVAYVA PAAIKGKCNL ECSAANNRVK LQPGQVYQYK VESSAGVLLA
GVDAIERRVR FEAEASVFAI DKCNFAVTVS KITLHGADDK KFSPAELLTN LAKPVKFALG
SENICTQEDD ATFSVNIKRA IASAFVNGGE DGSVTDHDIF GTCHSVVSVS QQGGVTIINR
ARNLNLCSGR ETLGHTLSGS VFNEASGIKS TPTLNGDYSS EVRLKGGVVD SATVDEEYRF
VAFSTASAGA RAKVQTKLRL SGNSKGAPKN VEAATVQRGI AFETPREGGA ATSQRLRDVI
REAVDSFADG VGANATSQFV DIVRLLRDTG KNDIKTTFQT IVSKSLHERS DLARKIYLDA
LFRTATGDAV EAIIDLLSGR AFTPQEQRLA MLSMNLVTSL DRDSINSFQK LTPSSPNVLP
EALLATGTLV RKYCDQYTCT DEQLDKVLDR FTGHLHQCQP RKKKEEDVIV TALKGIRNTH
GYIGRKLVDN VIACTQKNTK SRIRVAAIEA LEGVSCEKRV YNNLVQLLDD VAQDPELRLQ
AYLALTKCPT PQLADHLQKL LDGEEIQQVG AFITSHLASL RATTDPARQT AREVLGRVRT
AKRFPFDLRR YSHSRELSYA VDSLGLGASV DSNIIYSHSS FLPRSATVNV TGELFGNAFN
VLDLSVRQGN LDSVIERYLG PKGILSSKSP QQLYDFLKKT VEDAHKRTEG LLRGRRDVSK
ADLNAFAKNV ILPNDVTSSD LDLDVSVKFL GNELVFLSLG DDLPTTPDDV AAQLSKIVKE
FLDGATKFQR NFEAHALFVD GELSYPTAGG LPLRLTAHAT GVVGLETSGA IDIRRLWRDP
SQSPVQLKVV PSANLELVGA LLVDAYAVTS GIQVSGSVHT STGADVKVSF QEKPCKVDVK
ISMPRKKQEI FSINHDIVLY TRERGQQSVS VPLRFSSKRT AFNGCFDQLH RYTGVTFCTD
YNVTIPGNTG VAPFPLNGAN RIAVWLEVDS SYHFAFSHSH KDESLQYIRF TFDTPDSSDP
RTTTLAFESA TSPNIFVRAE LDSPYRKVMG EAGLANNEKE VALYAKAKDQ GNEYIAKIGF
TKDEAKREYS PILVVKTPAS RDNTALGYSV EGKIKVNDGG GQMRYDLQDI RLKGGYFTSN
PLTVSGTVTQ RGTAFDTDLK IDHRGDTGTV KGSLQFEANR LNLDLKVKCG WHANVQYKVS
YQTNEILNHL ELEYGYGSGG SHHIKALQQW RHKYSKYRLE ELLFNNELEL SHLPLKARLN
GNFVDGSVIK YDVGLEYGGK EASSKLDVKL NEKTKGDYAV EADASINKKK LSVIAKRIVQ
ENASKYSNRL FTSTGLSLEA NGVIGHRISA QEADIVADAK AQFGEKQQPY VAKFELKLKP
QGGNTHGSLS AGKNDLVTFK GTLNRKGNTQ DGNMQVTVKE ILEGSGDFTA TGGNGTATVN
LNVLKLSKGI KVVTNFAIEA PIYNVATEVF YDTANGGGRR TLRVDTRNLV ESQSFRSNNE
VEVFTERYVC NVEGALDGKA GDGVLTGQFD VTLPTGRKLS GSIKREVRPQ GDGIRGSNEV
AVSDKLPNNQ VRSLSLSSQL LNAKWSEKIF QAKHTVVYKD LDGKDVTVKL DLHHKAAKEN
TRAIDGDLSV AGSLFARSIK VTLRVPEYSQ DHADFNVAVK SEKDGDVQLV GRYVIGGRAK
ANEYDVTFSG SSKGDKARTI EVKSSGSFLT PQVDHGVYDT KWKLSVKTDG KESHVNVAGV
ANEDHANVKV DLKLHERDPV TVALTYNHEE TPDGQSGKCN LEAEVNYAKD EKIHGKAVLK
RTEGREIDLH ATLETPYEKA SNVVFNVKAA KTNEGVVRSA VDVTVNKDTY GLNSAVVLSD
ANPSVDLVVI YPKKEVKFFA GFARVGEKKY NGKVKIENLL DYNVDATGEI AAASIENFAA
KVDIDAPKLK LDKFHGELKS KHQGASKGVE VQASNGGKSI LTGFADYTVE QNKTLTVFEA
KGNVKFYEKE SEAHLKFIHH TLTQAENQET GVSFIVNAHL GPKSIVGELK ITDKNVQLKH
AACEKQQQCI HLDIQSTISQ ADLDSFKHQI VVSIDLRKLG YSHEFGLKAE TSRKGVELDH
TIEMHLQAQD KPQYQYSMYI HSKSAGVVVT LPERTIALEG VFERPETLFG KWDVSGALYL
DKKNKPHESV RVGLKAHTKE PKKGSGSFES ALTFAHPAIR TLSVTAAGAI DATAHEANVK
LNFDVFKTAA KEVVVVGRIA NTEKGRAFNV SASVDVTSKH GLDYRASGHA ALAPERRAAS
FQGDAKFAGV QGSALFSITP ADLYARITAL EEDLFVADAK IGDKSIAGQA TIRPFKCTPI
TMSGSAKGLT EAKVHLSRAN LVTVDGEFAI NRAASFKINS QKGDIFTAQV TLDQQHFLAS
KYQMNSYQMR QFLQEVQTTV KQDLENTKKH IEAKVSETRT HIAQQYGNIQ KEIPEFDAVA
KNIKEELSKI LQELEKDPSI KPIIDAAAKI CGVVAKTFAD LFEVTVQSLK KVSEIITSFY
GNLVEIFNAR ILPSLVEWYA AVEKILHTVY LDTVSLLSGT IERVAKALKD YEEDFNKVAK
VSSETIGRFV RGATELLTAV QKEIADLQRL VQDYVASLPG MIYSKRSTTL YSLNTTSLST
//
