ID A0A1B0GJT1_LUTLO Unreviewed; 1102 AA.
AC A0A1B0GJT1;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=ZZ-type domain-containing protein {ECO:0000259|PROSITE:PS50135};
OS Lutzomyia longipalpis (Sand fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC Lutzomyia; Lutzomyia.
OX NCBI_TaxID=7200 {ECO:0000313|EnsemblMetazoa:LLOJ006726-PA, ECO:0000313|Proteomes:UP000092461};
RN [1] {ECO:0000313|Proteomes:UP000092461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Jacobina {ECO:0000313|Proteomes:UP000092461};
RA Richards S., Qu C., Dillon R., Worley K., Scherer S., Batterton M.,
RA Taylor A., Hawes A., Hernandez B., Kovar C., Mandapat C., Pham C., Qu C.,
RA Jing C., Bess C., Bandaranaike D., Ngo D., Ongeri F., Arias F., Lara F.,
RA Weissenberger G., Kamau G., Han H., Shen H., Dinh H., Khalil I., Jones J.,
RA Shafer J., Jayaseelan J., Quiroz J., Blankenburg K., Nguyen L., Jackson L.,
RA Francisco L., Tang L.-Y., Pu L.-L., Perales L., Lorensuhewa L.,
RA Munidasa M., Coyle M., Taylor M., Puazo M., Firestine M., Scheel M.,
RA Javaid M., Wang M., Li M., Tabassum N., Saada N., Osuji N., Aqrawi P.,
RA Fu Q., Thornton R., Raj R., Goodspeed R., Mata R., Najjar R., Gubbala S.,
RA Lee S., Denson S., Patil S., Macmil S., Qi S., Matskevitch T.,
RA Palculict T., Mathew T., Vee V., Velamala V., Korchina V., Cai W., Liu W.,
RA Dai W., Zou X., Zhu Y., Zhang Y., Wu Y.-Q., Xin Y., Nazarath L., Kovar C.,
RA Han Y., Muzny D., Gibbs R.;
RT "Whole Genome Assembly of Lutzomyia longipalpis.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:LLOJ006726-PA}
RP IDENTIFICATION.
RC STRAIN=Jacobina {ECO:0000313|EnsemblMetazoa:LLOJ006726-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AJWK01022211; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJWK01022212; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJWK01022213; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJWK01022214; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJWK01022215; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EnsemblMetazoa; LLOJ006726-RA; LLOJ006726-PA; LLOJ006726.
DR VEuPathDB; VectorBase:LLOJ006726; -.
DR OrthoDB; 5405762at2759; -.
DR Proteomes; UP000092461; Unassembled WGS sequence.
DR GO; GO:0016010; C:dystrophin-associated glycoprotein complex; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0007154; P:cell communication; IEA:UniProt.
DR GO; GO:0050804; P:modulation of chemical synaptic transmission; IEA:UniProt.
DR GO; GO:0046716; P:muscle cell cellular homeostasis; IEA:UniProt.
DR GO; GO:0023052; P:signaling; IEA:UniProt.
DR CDD; cd16244; EFh_DTN; 1.
DR CDD; cd02334; ZZ_dystrophin; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 3.30.450.30; Dynein light chain 2a, cytoplasmic; 1.
DR Gene3D; 1.10.238.10; EF-hand; 3.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR015153; EF-hand_dom_typ1.
DR InterPro; IPR015154; EF-hand_dom_typ2.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR12268:SF27; DYSTROBREVIN, ISOFORM F; 1.
DR PANTHER; PTHR12268; E3 UBIQUITIN-PROTEIN LIGASE KCMF1; 1.
DR Pfam; PF09068; EF-hand_2; 2.
DR Pfam; PF09069; EF-hand_3; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF47473; EF-hand; 3.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF103196; Roadblock/LC7 domain; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 417..473
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT REGION 671..767
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 919..1030
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1051..1102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 862..912
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 680..698
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 711..734
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 939..958
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 971..994
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1051..1065
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1066..1102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1102 AA; 123266 MW; 2EDCB9679CE75C1F CRC64;
MHDRQINLDY TGLFGSLLMK ARRAVRLMDA NDTLLEIRVR TNKHETFITP DHHMEIEPRI
AVLQDLRLQS FDSIRFASYR TASKLRHIQK STNLHLVDIW NVIEAFRENG LNTLEPQSDV
SVARLETLVS SLYHNLNKRL PMAQQVPVDS KASLLLNWLL AAYTTDNSGK IKVFSIKVAL
ATMCAGKLME IEPRIAVLQD LRLQSFDSIR FASYRTASKL RHIQKSTNLH LVDIWNVIEA
FRENGLNTLE PQSDVSVARL ETLVSSLYHN LNKRLPMAQQ VPVDSKASLL LNWLLAAYTT
DNSGKIKVFS IKVALATMCA GKLVDKLRYV FSQISDGMGQ LLHYKLGEYL KEVLTLTAAV
YESPTFHYTE NLETELFPLD SKVTVNDFMG ALMSEPGPPC LVWLPLLHRM ASVENVVHPT
ICSVCHRENF TGFRYRCQRC HAYQLCQDCF WHGRVSLSHL TDHEVKEYST YKSPSKQIGH
SLRKSFRCVP DKPTQALPRF PEQPEKTLNL SHIVPPSPLP SHNGFADGGI MAGLFERSST
LDSRATGCSM ESAGTSLNRA AAAVMSNDEE HRLIARYAAR LAQENRTPNA TPSDNVSAVD
GARQQRELIA QLEAKNKEIM REIARLRRQQ EAEQMNQESP ALMNELRALR QRKGELEGHL
GALQDSRRQL MAQLEGLMRM LKNHQTSSPR STPNSSPRSG KSPPLPQGPQ NTIPRNSAHQ
TQIQQSSIVG GNLNDNLPQV GDGRPPYTAA APPPSNGTPH LGAGGRPIRT DLHYAADSVT
HAMSSLVREL NSVFLIFPIS VLKKTXXXXX XXXXXXXXXX XXAVMSNDEE HRLIARYAAR
LAQENRTPNA TPSDNVSAVD GARQQRELIA QLEAKNKEIM REIARLRRQQ EAEQMNQESP
ALMNELRALR QRKGELEGHL GALQDSRRQL MSQLEGLMRM LKNHQTSSPR STPNSSPRSG
KSPPLPQGPQ NTIPRNSAHQ TQIQQSSIVG GNLNDNLPQV GDGRPPYTAA APPPSNGTPH
LGAGGRPIRT DLHYAADSVT HAMSSLVREL NSEGSEDETT KNIQKTLDFD DSQNYQEWSE
KDNSNSQWQE QFAQWNLSGQ QK
//
