ID A0A1B0GNC0_PHLPP Unreviewed; 250 AA.
AC A0A1B0GNC0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
OS Phlebotomus papatasi (Sandfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Psychodoidea; Psychodidae;
OC Phlebotomus; Phlebotomus.
OX NCBI_TaxID=29031 {ECO:0000313|EnsemblMetazoa:PPAI004487-PA, ECO:0000313|Proteomes:UP000092462};
RN [1] {ECO:0000313|Proteomes:UP000092462}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Israel {ECO:0000313|Proteomes:UP000092462};
RA Fulton L., Warren W., Minx P., Wilson R., Clifton S., Abrudan J.,
RA Ramalho-Ortigao M., Lawyer P., Kamhawi S., Rowton E., Lehane M., Bates P.,
RA Valenzeula J., Dillon R., Lobo N., Collins F., McDowell M.A.;
RT "Phlebotomus papatasi, whole genome shotgun sequencing project.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:PPAI004487-PA}
RP IDENTIFICATION.
RC STRAIN=Israel {ECO:0000313|EnsemblMetazoa:PPAI004487-PA};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
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DR EMBL; AJVK01028617; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A1B0GNC0; -.
DR EnsemblMetazoa; PPAI004487-RA; PPAI004487-PA; PPAI004487.
DR VEuPathDB; VectorBase:PPAI004487; -.
DR OrthoDB; 2874082at2759; -.
DR Proteomes; UP000092462; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0048699; P:generation of neurons; IEA:UniProt.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR12027:SF98; PROTEIN WNT; 1.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00097; WNT1; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
SQ SEQUENCE 250 AA; 28660 MW; F57674D656D024C0 CRC64;
KYLRESLIED PSRNSLNSVD SIGSVSLDKR KSRSRLGSRW KWGGCSHNMD FGAEFSELFL
DARERAGDIQ SQINLHNNRV GRRAVANNMV IRCKCHGMSG SCQLKTCWRS APDFSVVGKF
LKQQFRRAVL VDQSNIGNGP PMVVVSHKNK KRRKNRPPRK TQGERMSNGG MRKLENSLFY
YQRSPNFCEK DPTSDIPGEN IRKEMQQDKF WERRLCFLVL RQRIQLNEGA ESGKMPLQVP
LVLLCGMPTL
//
